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Myopia is rising as a silent epidemic across the globe with marked ocular morbidity and pathological changes. The retinal nerve fiber layer (RNFL) thinning is indicative of glaucomatous damage; it remains uncertain whether RNFL thickness would vary with the refractive status of the eye. It is therefore important to investigate whether any correlation exists between RNFL measurements and axial length/refractive error in myopia. Purpose. To assess the peripapillary RNFL thickness by spectral domain optical coherence tomography (SD-OCT) and to determine the correlation between axial length and peripapillary RNFL thickness in myopia patients. Material and methods. A total of 100 patients (200 eyes) with low, moderate and high myopia (ave -3.58 ± 2.45 D) aged 15 to 40 years were examined to assess the peripapillary RNFL thickness by SD-OCT and to determine the correlation between axial length (AL) and peripapillary RNFL thickness myopia patients. Results. Average 360-degree RNFL thickness (mean ± SD) was 92.25 ± 10.04 μm. In the low myopic group this parameter was 98.82 ± 6.67 μm, in the moderate myopic group — 89.28±5.23 μm, and in the high myopic group — 78.54 ± 7.32 μm. The average 360-degree mean RNFL thickness in patients with AL < 24 mm was 100.06 ± 5.92 μm, in patients with AL between 24–26 mm — 89.48 ± 4.59 μm, and in patients with AL > 26 mm — 78.2 ± 6.77 μm. There was significant association between thinning of the average 360-degree RNFL thickness with increasing degree of myopia and AL (p < 0.0001). Conclusion. The study shows RNFL thickness decreases with increase in refractive error and increase in axial length of myopic eyes. The degree of myopia may affect the RNFL thickness differently.

Background: Therapeutic plants are an important source of medicine, and various active compounds were isolated from the plants. As per the Indian traditional system of medicine, many medicinal plants have been used for the management of various health disorders, including diabetes mellitus. Diabetes mellitus is a non-communicable disease that is also referred to as a lifestyle disorder that requires modifications in diet, exercise, and behavior along with medication. The present research work was designed to evaluate the impact of multiherbal formulations on blood sugar and body weight in albino rats. Three different formulations were prepared from five plant extracts (Allium sativum, Azadirachta indica, Phyllanthus emblica, Tamarindus indica, and Zingiber officinale). After daily administration of multiherbal formulations at a dose of 300 mg/kg b.wt. and the standard drug (Glibenclamide) at a dose of 5 mg/kg b.wt. for 15, 30, and 45 days, respectively, blood samples were collected from each rat and analyzed according to standard techniques (parameters). Blood sugar and body weight were measured. Results: There was a significant (p

The confinement of electrons in gold nanoparticles results in Surface Plasmon Resonance (SPR), which is characterized by electric field enhancement in the vicinity of these nanoparticles. This property has been extensively studied and applied in various fields. In our research, we conduct a detailed investigation of plasmonic coupling in spherical gold nanoparticles. Specifically, we use the Discrete Dipole Approximation (DDA) method implemented in DDSCAT to simulate the coupling of electric fields in a doublet of nanoparticles as a function of the distance between them. Our simulations show that the coupling of SPR between two nanoparticles occurs up to a separation of 12 nm. Moreover, we extend our simulations to study the coupling of nanoparticles in linear chains consisting of up to five nanoparticles and in clustered forms. Our results indicate that the SPR coupling in a linear chain occurs, and as the number of nanoparticles increases, the field enhancement also increases. However, we observe that this effect saturates after four nanoparticles in a line. Our study provides insights into the plasmonic coupling in gold nanoparticles, which can aid in the design and optimization of plasmonic devices for various applications.

Background: Many active chemicals have been identified in therapeutic plants, which are a valuable source of medicine. Many medicinal herbs, including hepatotoxicity, have been utilized to treat a variety of illnesses under the traditional medical system of India. Your liver may be harmed by toxic liver disorders. It's referred to as toxic hepatitis or hepatotoxicity. If you don't get care, it can result in severe symptoms or damage to your liver. Hepatotoxicity may be brought on by drugs, herbal supplements, chemicals, solvents, and alcohol. The goal of the current study was to assess how multiherbal formulations affected hematological markers in albino rats who were experiencing hepatotoxicity caused by carbon tetrachloride. Five plant extracts (Curcuma longa, Allium sativum, Phyllanthus emblica, Solenum nigrum, and Ocimum tenuiflorum) were combined to create three distinct formulations. Blood samples were taken from each rat and examined using conventional procedures (parameters) following daily administration of multiherbal formulations at a dose of 200 mg/kg b.wt. and the reference medicine (Silymarin) at a dose of 25 mg/kg b.wt. for 7, 14, and 21 days, respectively. Measurements included hemoglobin, PCV, DLC, TLC, ESR, and PLT count. Results: When hepatotoxicity-induced rats were compared to normal controls, there was a substantial (p

Acute lethality usually determined as LD50 is defined as median dose predicted to kill 50 percent of a given test population. LD50 is a statistical estimate of the number of milligram of toxicant per kilo gram of body weight administered by any of the methods like oral, dermal, inhalation, or intravenous and is sufficient to kill 50 percent of the large population of test animals usually within certain time. Determination of LD50 has always been a much controversial subject among biologists and animal ethicists due to painful treatments on large number of animals. However, to assess the toxicity of various chemicals on different organisms Median lethal dose is still being used by toxicologists to determine acute lethality to non-target organisms. In the present study we aimed to determine the LD50 of two carbamate insecticides bendiocarb and carbaryl on a non-target species Calotes versicolor a reptilian model. An approximate LD50 was initially determined as a pilot study by a so called ‘staircase method’ using only 2 animals (for each dose) and increasing the doses of the drug. Five doses 10, 15, 20, 25, 30 mg/kg body weight for bendiocarb and 50, 60, 70, 80, 90 mg/kg body weight for carbaryl were chosen for determination of LD50 starting from no death to 100% mortality. Intraperitoneal LD50 value calculated by regression analysis is 15.57 and 64.97 mg/kg body weight for bendiocarb and carbaryl respectively in male Calotes versicolor. The result confirms that bendiocarb is more potent than carbaryl in Calotes suggesting that bendiocarb may cause death even at smaller doses in comparison to carbaryl. Our results will help in adding to the fact sheet related to carbamate toxicity in reptiles.

The Auditor General of South Africa (AGSA), a statutory body that evaluates public sector information systems, is the main corporate governance instrument in the study. The different methods of corporate governance are explained in this article. The article examines the barriers to improving public sector information systems. Our analysis will focus on the efficiency of information systems in the public sector, closely linked to South Africa’s National Development Plan 2030 and the Medium Term Strategic Framework, critical measures to achieve success. The study uses Atlas.ti 7 for qualitative textual analysis. This software analyses textual data from the 2017–2021 AGSA reports.This thematic study highlights the micro and macro challenges faced by South Africa’s public sector governance institutions. The problems stem from deficiencies in the information system, changes in the leadership, and a lack of transparency and access to information. We also face smaller issues such as a lack of executive accountability for their decisions, inadequate technology skills, ineffective project management, no disaster recovery procedures, declining IT governance and delays in filling key IT positions.The study suggests promoting a transformative mindset to raise awareness of the critical role of information technology in public sector management. It also highlights the need to identify South African corporate governance practices that hinder information systems. The paper aims to improve the corporate governance framework for information systems in order to maximise the efficiency of the public sector.

Diabetes Mellitus (DM) presents a significant global health challenge, with escalating prevalence rates and associated morbidity and mortality. Despite medical advancements, the mortality rates continue to rise, necessitating a deeper understanding of the pathophysiology and potential therapeutic targets. Copper, a vital trace element, plays an important role in various metabolic processes and homeostatic functions within the human body. Dysregulation of copper metabolism has been implicated in the pathogenesis and progression of DM, contributing to oxidative stress, insulin resistance, altered glycemic control, and metabolic abnormalities. The present review provides an illustrative overview of the role of copper in DM, elucidating its impact on oxidative stress, insulin resistance, glycemic control, and metabolic disturbances.

This comprehensive review explores the multifaceted realm of Prussian Blue, a pigment with a rich history and varied applications tracing its origins, artistic applications, and chemical properties. Beginning with its origins as a laboratory creation, the paper traces its evolution into a revered pigment in the artistic world. The review explores the electronic transitions responsible for Prussian Blue's deep blue hue, shedding light on the intricate chemistry behind its vivid coloration. Additionally, the pivotal role of iron ions in determining the pigment's properties is examined in detail, highlighting the importance of precise composition in achieving desired color characteristics. Challenges in the reintegration of Prussian Blue into conservation and restoration projects are also explored, emphasizing the importance of careful preservation techniques to maintain the pigment's integrity and vibrancy. The review discusses the pigment's lightfastness and stability, addressing common issues such as fading and discoloration over time. A notable phenomenon of bronzing particularly associated with Chinese Blue has been characterized by the appearance of yellow or brown hues on the surface of the pigment, that has puzzled artists and conservators for centuries. The review delves into the underlying causes of bronzing, examining factors such as environmental conditions, pigment composition, and application techniques. The review explores the pigment's interactions with other blues and whites, offering insights into the spectrum of shades achievable through careful color mixing and layering techniques. The paper revisits the perennial debate surrounding the permanence of Prussian Blue. While some argue for its enduring stability and longevity, others point to instances of fading and discoloration observed in historical artworks. The manuscript navigates these conflicting perspectives, providing an understanding of Prussian Blue's permanence in different contexts. Prussian Blue stands as a testament to the symbiotic relationship between science and art, where its molecular structure and vibrant shades continue to inspire both chemists in laboratories and artists in studios. The Prussian Blue emerges as a captivating convergence of art and chemistry that has left an indelible mark on laboratory benches and artists' canvases. The unique interplay of ferric and ferrous ions, not only renders a deep blue color but also makes it sensitive to the variation of its environment. The interplay of its refractive index, bronzing tendencies, and tinting strength shapes its artistic applications, influencing the vibrant hues it contributes to diverse palettes. The permanence paradox surrounding Prussian Blue underscores the importance of precision in its preparation. As artists mix and blend, the pigment unveils its versatility, playing a pivotal role in color harmonies and shade variations. Beyond its role in art, Prussian Blue finds diverse applications in medicinal and industrial contexts. From its use as an antidote for heavy metal poisoning to its incorporation into high-performance materials such as batteries and sensors, Prussian Blue continues to demonstrate its versatility and utility in modern society. The review highlights these varied applications, showcasing Prussian Blue's enduring relevance and evolution beyond its historical roots.

Azadirachta indica, also known as Neem is an evergreen tree that is native to the Indian subcontinent. It has been traditionally used for various medicinal purposes, including wound healing, fever reduction, and treatment of skin disorders. It has been widely recognized for its various medicinal properties. In this review, A comprehensive overview of the biochemical properties of Neem and its potential benefits are provided. The chemical constituents of Neem including Azadirachtin, Nimbin, and nimbolide, and their biological activities, such as antimicrobial, antioxidant, and anticancer effects are discussed. The potential applications of Neem in medicine, agriculture, and cosmetics are explored. This review highlights the importance of neem as a natural resource with numerous potential benefits for human health and the environment.

Third-generation solar cells have emerged as a potential solution to the effectiveness and stability issues encountered in conventional solar technology. This study focuses on the characteristics of copper-zinc-tin-sulfide (CZTS) thin films inside this innovative architectural framework, which is an important step toward improving third-generation solar cells by incorporating a p-type silicon layer. This integrated method provides a versatile and manageable setting for film deposition, underscoring the effort put into creating high-quality CZTS thin films. Using X-ray diffraction (XRD), the study assessed the structural change of CZTS films after annealing, finding that kesterite phases were dominant. Images captured by a scanning electron microscope (SEM) reveal the microstructure and surface morphology of CZTS-coated Silicon nanowires (Si-NWs). A detailed analysis of the current-voltage characteristics provides evidence of the operational potential of the Si-NWs-CZTS coated solar cell. Significant performance parameters observed include a Voc value of 0.45 ± 0.02V, Isc value of 8.25 ± 0.30 mA/cm², FF value of 24 ± 2%, and η value of 1.0 ± 0.1%. The encouraging results indicate the capacity of using P-type silicon to enhance the performance of third-generation solar cells.

The research aims to look at the linear and nonlinear causal relationships between Brazil’s accumulated international reserves and economic growth from 1989 Q1 through 2021 Q4. For empirical investigation, this study employed econometric procedures such as the Augmented Dickey Fuller and Zivot-Andrews unit root tests, the linear Granger causality test, Johansen’s cointegration test, the BDS test, and the nonlinear Granger causality test proposed by Hiemstra and Jones. The study concluded that there is a bidirectional linear and non-linear causality between foreign exchange reserve and economic growth. This study fills the gap in the literature by exploring the nonlinear relationship between international reserves and economic growth, while earlier studies primarily explored linear relationships. Foreign trade policymakers can utilize the model developed here to formulate applicable policies about foreign exchange reserves. Based on the findings, the study proposes that Brazil can accrue foreign reserves if surplus assets are invested in alternate sources such as economic infrastructure projects and regional infrastructure development.

Hydrocephalus is a central nervous system disorder which most commonly affects infants and toddlers. It starts as an abnormal build-up of cerebrospinal fluid in the ventricular system of the brain. Hence, early diagnosis becomes vital, which may be performed by Computed Tomography (CT), one of the most effective diagnostic methods for diagnosing Hydrocephalus (CT), where the enlarged ventricular system becomes apparent. However, most disease progression assessments rely on the radiologist's evaluation and physical measures, which are subjective, time-consuming, and inaccurate. This paper develops an automatic prediction utilizing the H-detect framework for enhanced accurate hydrocephalus prediction. This paper uses a pre-processing step to normalize the input image and remove unwanted noises, which can help extract valuable features easily. The feature extraction is done by segmenting the image based on edge detection using triangular fuzzy rules. Thereby, the exact information on the nature of CSF inside the brain is highlighted. These segmented images are saved and again given to the CatBoost algorithm. The Categorical feature processing allows for quicker training. When necessary, the overfitting detector will stop model training and thus efficiently predicts Hydrocephalus. The outcomes demonstrate that the new H-detect strategy outperforms the traditional approaches.

This paper is devoted to investigate five dimensional homogeneous and isotropic FRW model with varying gravitational and cosmological constant with cosmic time. Exact solution of the Einstein field equations are obtained by using the equation of state p = (γ −1)ρ (gamma law), where γ which is an adiabatic parameter varies continuously as the universe expands. We obtained the solutions for different values of curvature K = 0, 1,−1 by using a(t) = R0(1 + α2t2)n, where α, n and R0 are positive constants. Behaviour of the cosmological parameters are presented for different cases of the models. Physical interpretation of the derived model are presented in details. Interestingly the proposed model justified the current cosmological observations with dark energy.

In this report, we have investigated the CsMgCl3 compound with the help of the WIEN2K software package. The structural and electronic properties are performed using the full potential augmented plane wave (FP-LAPW) method with the generalised gradient approximation (GGA) approximation as exchange correlation potentials. We used the Birch-Murnaghan equation (BME) to find the structural properties of the material. These include the lattice parameter, the bulk modulus, the first derivative of the bulk modulus, the minimum energy, and the volume. The structural properties match up with the experimental data. Electronic properties in terms of the band structure (BS) and total and partial density of state (T-DOS and P-DOS) profiles of CsMgCl3 using GGA potentials exhibit an indirect wide energy band gap of 5.35 eV. All these properties show that the CsMgCl3 compound is used as a perovskite in solar cells.

Specific impact of sprint training (ST) on bone health has yet to be fully explored, in particular how it affects bone mineral density (BMD) and bone structure.Aim. To investigate the ST and bone health relationship between athletes of different training intensities and nonathletes of different ages.Materials and methods. A search of databases PubMed, Embase, and Pedro was conducted from January 2009 to August 2023. The full texts of all potentially relevant studies were obtained and evaluated by three independent reviewers for inclusion.Results. The comprehensive review of eight studies indicates a positive influence of ST on bone health. Sprinters show higher cortical and trabecular BMD in the tibia than controls, with a noted age-related decline in BMD. Short distance runners demonstrate significantly better BMD, counter-movement jump performance, and grip strength compared to long-distance runners. These benefits are consistent across various age groups, including older athletes, with minimal age-related changes in mid-tibial BMD. ST is also associated with a 21% increase in tibial stress-strain index, indicating sustained bone strength, and a reduction in fracture risk in the elderly through downregulation of fracture-related microRNAs.Conclusion. ST significantly enhances bone health, particularly in improving BMD and bone microarchitecture. Incorporating ST into exercise routines may benefit athletes and older individuals. Further research is essential to understand the mechanisms and develop optimal training protocols for bone health.

The purpose of this Erratum is to correct a misprint presented in the original article.

The most common kind of sexual or physical abuse suffered by women is that by a partner. Human rights are violated when males or boys use violence against women or girls. When it comes to domestic abuse, it is estimated that one in three women will experience some kind of gender-based violence at some point in their lives. The number of women who have been abused by a romantic partner or a non-relationship sexual partner is estimated to reach 736 million. For years, the world’s leaders have recognised its seriousness. In 1995, the Beijing Declaration and Platform for Action said that violence against women must be eliminated. Within the “UN’s 2030 Agenda for Sustainable Development,” a worldwide goal to abolish “all kinds of violence against women and girls in public and private spaces” was added. Global action was called for in 2016 by the “World Health Assembly’s” Resolution 69.5, which urged a national multisector approach to combating violence against women and young girls. In spite of all of these responsibilities, 49 countries still don’t have a clear policy on domestic abuse. Lower and lower-middle-income women nations are particularly vulnerable to this violence, which has long-term effects on their health and well-being. In the world’s poorest nations, women aged 15 to 49 have a lifetime frequency of domestic abuse of 37 percent. One in every four women who have ever been in a relationship has been a victim of domestic abuse at some point in their lives.

BACKGROUND: The COVID-19 global pandemic exposed gaps in the treatment of common physical and mental disorders that had to do with things like lockdowns, poor convenience, fear of contracting COVID, and economic constraints. Hence, to address these treatment gaps while also limiting exposure to the COVID-19 infection, telemedicine in the form of telephone and internet consultations has increasingly become the recourse around the world. Our center adopted this trend and also launched a telepsychiatry initiative in order to better cater to the needs of patients with pre-existing mental health disorders and to ensure regular follow-ups and compliance with prescription regiments. AIM: The present study aimed to assess the level of patient satisfaction with the online psychiatric services/telepsychiatry. METHODS: The sample consisted of 100 patients with pre-existing mental health disorders. This was a cross-sectional study lasting 6 months. The DigiDoc app by Hospital Information Software (HIS) software, which is used to manage a patients appointment schedule, relevant clinical and lab details, along with follow-up prescriptions, was used to follow the selected patients for the purpose of this study. This software also provides a digital platform for video calls for online consultation. The Client Satisfaction Questionnaires-8 (CSQ-8) was employed to collect patient data for analysis. RESULTS: The mean total CSQ-8 score of the study sample was 21.015.80 (832), which corresponds to a low-to-moderate level of satisfaction with online psychiatric services/telepsychiatry. Most patients (45%) reported low satisfaction levels, followed by 37% who reported moderate levels of satisfaction. Only 18% of patients reported higher satisfaction with telepsychiatry. CONCLUSION: Despite the psychiatrists ability to provide adequate professional advice and psychoeducation through online psychiatric services, patients level of satisfaction proved moderate-to-low. This suggests a need to design standard protocols and guidelines in the search and provision of consultation services on online psychiatric service platforms that could help enhance patients levels of satisfaction.

Introduction. Prior studies have connected entrepreneurship to the economic growth of regions. This fact has led to an increase in academic interest on regional entrepreneurship in Russia and around the world. However, these studies are highly diverse in their research scope, goals, methodologies and results. Therefore, the goal of this paper is to provide some coherence and synthesis to academic research on regional entrepreneurship in Russia. Materials and Methods. Using a bibliometric method of analysis, this research presents an empirical review of academic studies on entrepreneurship in Russian regions. To maintain a quality threshold, our research focus was limited to studies indexed in the Scopus citation database. We analysed 361 articles from 2006 to 2022. The research includes a thorough performance analysis and a scientific mapping of the field. Results. Our results show that the main thematic clusters include entrepreneurship, innovation system, government support, knowledge economy and competitiveness, while emerging themes include pandemic, digitalisation, higher education and investment attractiveness, among others. Also, we identified a number of research gaps, particularly in the sociological research of entrepreneurs, and propose suggestions for future research. Discussion and Conclusion. This article provides an important resource for scholars interested in the study of regional entrepreneurship in Russia and around the world.

Herein, we have formulated a simplistic semi-empirical model for Vicker’s hardness of rare earth based pyrochlore compounds. We have considered the structured 97 pyrochlore compounds for Vicker’s hardness calculations. The plasmon energy (ħωp) depends on basic parameters of the material such as Ne-effective number of free electrons per unit volume participating in plasma oscillations, e-electronic charge and m-mass of an electron. The proposed model predicts that the experimental and theoretical values of Vicker’s hardness increases as plasmon energy of pyrochlore increases. We have found that the calculated values are in better agreement with available experimental and theoretical data, which supports the validity of the model. This model supports the modeling of emerging functional pyrochlore compounds and helps to understand their mechanical properties for excellent thermal stability, superconductivities, batteries, ferroelectricity, water spitting, high ionic conductivity, good photoluminescence, inherent oxygen vacancies, exotic magnetism, and now-a-days most importantly in nuclear waste encapsulation and aerospace industry

This article uses the FP-LAPW approach within the DFT method, and the quasi-harmonic Debye model to investigate the electronic and thermodynamic properties of intermetallic rare earth materials (such as SmInZn, SmInCd, and SmTlZn). Thermodynamic properties were determined by the quasi-harmonic Debye model, whereas the FP-LAPW approaches within DFT method were utilized to derive electronic properties. The calculated structural parameters and the available experimental data have been examined, and it was observed that there was a good agreement between available experimental and calculated values of structural parameters. The electronic behavior of SmInZn, SmInCd and SmTlZn compounds shows the metallic character. We have examined a few thermodynamic characteristics. All calculated characteristics were found to match experimental or theoretical calculations.

Heat shock proteins (Hsps) responses against stress conditions. Melatonin completes its stress relieving activities via its MT1 and MT2 receptors. The present study delineates the expression pattern of Hsp70/Hsc70 and MT1/MT2 receptor proteins along with the AANAT gene expression in the splenic tissue of mice subjected to hyperthermic stress in a temperature dependent and time dependent manner. In vivo thermal stress resulted increase in expression of Hsp70, Hsc70 and MT2 receptors proteins in both temperature dependent and time dependent manner. Optimum heat exposure at 430C and maximized Hsps expression was observed after 5 hours of heat exposure. Heat stress caused increase in AA-NAT gene expression of the splenic tissue resulted in the synthesis of melatonin which might act as signal molecule for upregulating the activity and rise of the stress responsive genes and proteins like: Hsp70/Hsc70, whereas simultaneous increase of MT2 expression shows its possible involvement in such mechanism.

High Resolution (HR) images have numerous applications, such as video conferencing, remote sensing, medical imaging, etc. Furthermore, a few challenges with the super resolution algorithms of magnetic resonance brain images are now obtainable, namely, low sensitivity, significant frequency noise as well as poor resolution. To fix these problems, a Convolutional Neural Network (CNN) based Discrete Cosine Transform (DCT) singular frame quality improvement method is described. There are two stages in this proposed method, involving training and testing. During the training stage, the HR, and Low Resolution (LR) pictures are employed as input, and they are preprocessed to create blocks of images. The histogram and DCT are used for extracting the features from the LR and HR blocks, and these extracted features are assigned with class id. The CNN, which extracts the features and allocates class id, receives its feature extractor as its final input. An LR input image is once more divided into [2 × 2] blocks during the testing stage, so each block histogram and DCT feature are estimated. Each feature vector is fed into the neural network as well as the results are contrasted with a set of feature vectors that have been recorded, in addition to the class id that has been allocated to a certain vector. In order to generate a Super resolution image with an LR image, a relevant HR block is then swapped out for this LR block. These results indicated that the initial dataset can achieve 22.4 and 19.5 Peak Signal to Noise Ratio (PSNR) and Root Mean Square Error (RMSE) values while measuring the effectiveness of this proposed method using RMSE and PSNR. Then, the second dataset illustrates that the PSNR and RMSE values are 20.1 and 25.5. For the third dataset, the values are 45.7 and 12.3, respectively. However, the presented method works better than the neural method of Super Resolution Channel Spatial Modulation Network and resolution enhancement technique.

The study objective: the study objective is to examine the use of artificial intelligence (AI) in the diagnosis, treatment, and prognosis of Colorectal Cancer (CRC) and discuss the future potential of AI in CRC. Material and Methods. The Web of Science, Scopus, PubMed, Medline, and eLIBRARY databases were used to search for the publications. A study on the application of Artificial Intelligence (AI) to the diagnosis, treatment, and prognosis of Colorectal Cancer (CRC) was discovered in more than 100 sources. In the review, data from 83 articles were incorporated. Results. The review article explores the use of artificial intelligence (AI) in medicine, specifically focusing on its applications in colorectal cancer (CRC). It discusses the stages of AI development for CRC, including molecular understanding, image-based diagnosis, drug design, and individualized treatment. The benefits of AI in medical image analysis are highlighted, improving diagnosis accuracy and inspection quality. Challenges in AI development are addressed, such as data standardization and the interpretability of machine learning algorithms. The potential of AI in treatment decision support, precision medicine, and prognosis prediction is discussed, emphasizing the role of AI in selecting optimal treatments and improving surgical precision. Ethical and regulatory considerations in integrating AI are mentioned, including patient trust, data security, and liability in AI-assisted surgeries. The review emphasizes the importance of an AI standard system, dataset standardization, and integrating clinical knowledge into AI algorithms. Overall, the article provides an overview of the current research on AI in CRC diagnosis, treatment, and prognosis, discussing its benefits, challenges, and future prospects in improving medical outcomes.

The India-France partnership has witnessed significant progress since 2014, particularly under the leadership of President Emmanuel Macron and Prime Minister Narendra Modi. The two countries have deepened their collaboration in a wide range of areas, including defence, space, energy, and technology which also impacted their cultural relations. This research provides an analysis of the strategic cooperation between India and France in the post-2014 period, with a focus on the achievements, challenges, and prospects for future collaboration. The data is drawn from a range of primary and secondary sources, including official statements, reports, and media coverage. It begins with an overview of the historical context of India-France relations and the evolution of the strategic partnership in recent years. It then examines the key areas of cooperation between the two countries, highlighting the progress made in each of these areas. Finally, the research explores the future prospects for the India-France partnership, particularly in the context of the changing global order and the growing importance of the Indo-Pacific region. It concludes that the India-France partnership has the potential to be a significant force for stability, prosperity, and security in the region, but will require sustained efforts from both countries to overcome the challenges and capitalize on the opportunities.

The service of the Orthodox clergy on the Dobroflot vessels remains under-studied in the history of the Russian Orthodox Church. This publication is the second in a series designed to fill this historiographic gap. The article highlights the state of the church property of the Volunteer fleet ships, on the example of the ministry of a cleric of the Yekaterinburg diocese, priest Georgy Levitskiy. Acceptance of church utensils was the first thing that a clergyman had to do upon taking office. The article is mainly based on the notes of priest Georgy, since he was assigned to vessels four times (of which three times to the steamboat Saratov) and left detailed descriptions of each voyage. The Cleric’s Notes are the largest source on the service of the naval clergy of the Dobroflot and allow not only to find out the situation with church utensils in a given year, but also to see how its state changes over time. For comparison, the notes of priest Alexei Livanskiy and the report of priest Nikolai Dyakov were used. Owing to these materials, it can be assumed that the diligence of priest Georgy and the care of the sailors contributed to the fact that the church equipment on the steamer Saratov was not only in decent condition, but the number of liturgical items increased from year to year. However, the situation with church property was not so favorable on other ships.

Background: The efficacy of pregabalin in acute post-surgical pain management is well demonstrated. As, the use of pregabalin is officially not approved and hence, there is no dosing guideline as well. Aim: To determine whether single preoperative administration of different doses of pregabalin (150 mg to 300mg) could decrease postoperative pain intensity following spinal surgery. Materials and Method: In this prospective, randomized double-blinded study, a total 60 patients undergoing spinal surgery were selected and randomly assigned any of these four groups of 15 each; group A (received placebo drug), group B (received pregabalin 150mg), group C (received pregabalin 200mg) and group D (received pregabalin 300mg). All the groups received the said drugs (coded as it was double-blinded study) in the same manner and two hours prior to operation. The patients were followed for pain scores on visual analogue scale (VAS), time to rescue analgesia and side effects as secondary outcomes. Results: Patients in pregabalin dose ranging group had lower pain in the initial hour of recovery. However, the pain scores subsequently decreased and became similar in all groups. Time for the requirement for analgesic was longer in pregabalin 300mg group when compared with other study groups. Conclusion: A single dose of 300 mg pregabalin given 1–2 hours prior to surgery is superior to placebo after spinal surgery.

The brain is extremely complicated three dimensional structures made up of interconnected neurons and neuroglia cells. It entails all type of functions of our body whether we are healthy or in disease conditions. Brain is accountable for our connectivity with the surroundings; all this is performed by an organized and systemic electrical activity of neurons by which they communicate messages to and from the brain. The abnormal electrical activity leading to the intense outburst of impulses, results in the development of epilepsy. Epilepsy is typified by recurrent, unprovoked seizures as a result excessive, hypersynchronous discharge of neurons occurs in the brain. Nearly 1% of the population throughout the worldwide is suffering from epilepsy and almost 75% begins at childhood. The patients almost one third are resistant to current available antiepileptic drugs. We don’t have the deep knowledge of the pathophysiology of the disease which can prove useful in further research for drugs with new mechanisms of action for diseases. This paper covers the role various neurotransmitters and neuropeptides in the pathophysiology of epilepsy. Our objective is to introduce the scientists with that aspect of the disease which may prove useful for further development of new drugs of epilepsy to overcome the resistance shown by the patientsorithm.

Seasonal variations in the physiological processes help animal to adapt to the environmental condition, however, informations on this subject in reptiles are scarce. In the present study, garden lizards (Calotes versicolor) were used to study the annual variation in blood immune responses and changes in the lymphoid organs. The lizards were weighed, anaesthetized under mild anesthesia and blood was collected in heparinized syringe. Blood was then processed for determining total leucocyte count, differential leucocyte count and nitroblue tetrazolium reduction test (Slide assay) for assessment of reactive oxygen production by leucocytes. For histomorphological studies, spleen, thymus and testes were excised rapidly, cleaned and weighed and their weight was transformed to thymosomatic, splenosomatic and gonadosomatic indices respectively. Total leucocyte count did not change significantly, however, differential leucocyte count varied during different seasons. Thymosomatic index was lesser in summer and rainy months. Splenosomatic index started increasing from May and remained high up to August (the hot and humid months of the year and reproductively active months). Gonadosomatic index was low from September to March. It started increasing from April and remained at highest level from May to August. Environmental factors play an important role in body physiology, oxidation, and intermediary metabolism and gonadal activity of all the vertebrates, including reptiles. The annual variation in physiology is pivotal to help animals cope with seasonal stressors.

Introduction: the relevance of determining the effectiveness of early rehabilitation of patients after an ischemic stroke is high, as it solves a number of important medical and social problems of society. The aim: to determine the possibilities and effectiveness of early rehabilitation of patients after an ischemic stroke according to the data of literary sources. Materials and methods: the research was conducted based on the results of the analysis of the world results of scientific research and the existing mechanisms and documents of international societies for determining the possibilities and effectiveness of early rehabilitation of patients after an ischemic stroke. The search for scientific information was performed using domestic and foreign Internet resources of Google Scholar, PubMed, Medscape, Scopus and Web of Science databases, etc. The results of the study: It was determined that the primary and quite effective measure in the treatment of patients after an ischemic stroke is the early start of rehabilitation measures, which improves the survival of brain cells due to an increase in cerebral blood flow, which reduces ischemic necrosis of neurons and revitalizes part of neurons and significantly reduces the post-stroke level disability of patients. It was established that a significant yet undetermined issue in early rehabilitation is the effectiveness of early mobilization and its intensity, and the effectiveness of the rehabilitation strategy is entirely based on the correct combination of the time from the onset of the stroke and the intensity of mobilization Conclusions: the study determined that early rehabilitation intervention in ischemic stroke is significantly effective and economically feasible, and the effectiveness and feasibility of early intensive mobilization is currently a rather controversial issue.

Salinity stress negatively affects the growth and development of wheat leading to diminished grain yield and quality. Salt stress during reproductive stage is one of the significant factors leading to the drastic reduction in grain yield. The objective of this study was to investigate the biochemical responses of pre-anthesis stage salt stress and yield related traits in KRL1-4 salt tolerant and UP2338 salt sensitive cultivar of Wheat. Three different levels of salinity stress (100, 200 and 300 mM NaCl) was induced. Untreated plants were kept as control. Samples were analyzed at pre- anthesis stage (50 DAS and 60 DAS) for various biochemical parameters viz., proline content, total reducing sugar content, total nitrogen content and total protein content. Yield related traits harvest index, tiller numbers per plant, spike height and spike weight were recorded at maturity stage. The amount of proline and reducing sugar increased with increasing salinity, the increase being more in tolerant than in sensitive cultivar. Total nitrogen and total protein content, however, decreased with increasing salt concentration and reduction being more in sensitive than in tolerant cultivar. Yield attributes were affected negatively. The effect was more pronounced in sensitive cultivar compared to tolerant.

The research aims to examine the unexpected changes in stock prices due to external shocks given to the macroeconomic variables to forecast future stock market returns. The study applies two econometric models such as «Variance Decomposition» (VDC) and «Impulse Response Function» (IRF) for examining the exogenous shocks in macroeconomic variables respond to changes in stock prices. Monthly time series data of five significant macroeconomic variables Real Exchange Rate, Interest Rate, Consumer Price Index (CPI), Crude Oil Prices, and Trade Openness, taken as independent variables and BSE SENSEX as a dependent variable. The research period is from Jan 2009 to Dec 2019. The study has taken the responsibility to reveal a few strong evidences for changes in stock prices due to exogenous shocks in Exchange Rate, Trade Openness, Inflation, and Interest rate along with crude oil prices. According to the results, changes in the stock market are due to external factors like changes in dividend policy or capital loss, and some changes in the stock market are due to its own innovative shocks. This study suggests to reduce unexpected changes in stock prices frequently, companies should control capital loss and focus on stable return/dividend policies. There are divergent views in the literature review in the context of measures of these variables, however no research has been done on exogenous shocks in macroeconomic variables to BSE SENSEX for the Indian stock market with this particular data set and duration.

The history of the Solovetsky Monastery is full of bright events, which are covered in detail in historiography. However, the participation of the monastery in the First World War practically did not attract the attention of researchers. The monastery, being far from the fighting on the front line, found itself in the thick of events unfolding in the Arctic Ocean. Caravans of foreign ships with military cargo went to Arkhangelsk, and the German command sought to disrupt these transportations. Since the Russian Navy in the Russian North were limited to the small vessel Bakan, the mobilization of steamships of private owners began, one of which was the Solovetsky Monastery. As a result, the attracted merchant ships managed to form the Arctic Ocean Flotilla. The Solovetsky ships Vera, Solovetsky and Mikhail Archangel and their crew were not prepared to solve military problems, but they carried out a dangerous and routine service, without which the functioning of sea lanes in such a difficult time would have been impossible. The ship Vera played a special role in the organization of convoys, as it became the flagship of the Minesweepers party of the White Sea. This article is devoted to the fate of this vessel, as well as the contribution of the monastery to the defense of the Russian North.

Agriculture is regarded as one of the most crucial sectors in guaranteeing food security. However, as the world’s population grows, so do agri-food demands, necessitating a shift from traditional agricultural practices to smart agriculture practices, often known as agriculture 4.0. It is critical to recognize and handle the problems and challenges related with agriculture 4.0 in order to fully profit from its promise. As a result, the goal of this research is to contribute to the development of agriculture 4.0 by looking into the growing trends of digital technologies in the field of agriculture. A literature review is done to examine the scientific literature pertaining to crop farming published in the previous decade for this goal. This thorough examination yielded significant information on the existing state of digital technology in agriculture, as well as potential future opportunities.

The paper is concerned with some aspects of politeness in the request act by the pragmatic connotations of syntactic structures in Hindi and Persian. Considering the role of politeness as an explanation for the deviation from the Grice’s cooperative principle, the main question of the paper is whether Leech’s maxims of politeness operate on the syntagmatic and paradigmatic relations and whether there is any hierarchy in their manner of application. To answer the abovementioned question the main hypothesis of the research posits that Leech’s maxims of politeness have a structure of hierarchy in both Persian and Hindi. Considering the Pandharipandes' (1979) hierarchy of the degree of politeness proposed for Hindi, this paper aims to develop a similar hierarchy of the degree of politeness for Persian and to analyze the Leech’s maxims operating in the respective hierarchies of politeness. The general theoretical framework adopted for the present study is based on Lakoff (1972), and Leech (1980). Whereas the findings of this research indicate a hierarchy in Hindi and Persian at the syntagmatic planewith regard to their respective Leech’s maxims,no such hierarchyis detectable for paradigmatic relationwhichholds good for all types of social situations.

Friction Stir Processing (FSP) is a technology in which the microstructure of a material, as well as the mechanical properties of this material, is enhanced by the action of friction with a special tool. There are many applications for FSP materials which are in high demand in various industries, including aerospace, shipbuilding, instrumentation, and many others. The paper presents a study of a hybrid composite made from silicon carbide powder and rice husk (RHP) as reinforcement, included in the Al6082 aluminum alloy. The study of the characteristics of the fabricated composite was performed using an optical microscope, field emission scanning electron microscope (FESEM), X-ray diffraction (XRD) method. Tensile strength (UTS) and hardness were determined. It was revealed by microscopy that a modification of the microstructure occurs on the surface of the composite. X-ray diffraction analysis showed the presence in the spectrum of elements similar to the Al/SiC/RHP hybrid composition. It is shown that UTS tensile strength and Brinell hardness is being increased by factors of 1.36 and 1.75, respectively, compared to base aluminum material.

The paper attempts to trace the evolution of the concept of Corporate Social Responsibility (CSR) and seeks to gather how it turned out to be a boon for the developing nations of the world, particularly countries like India. By the path-breaking promulgation of the Companies Act, 2013, CSR was made mandatory in India, for companies meeting the financial thresholds mentioned in Section 135 of the Act. The author seeks to study the journey of CSR in India, the present law, and the latest amendments made to the same in recent times. The paper evaluates the rationale behind the mandatory CSR law and how it can be a game-changer in India Inc.’s commitment to social causes. The author has also suggested how the mandatory CSR regime in India can be further strengthened to contribute meaningfully, particularly in the fields of education and healthcare, through better project identification, stronger execution linkages, an overhaul of the board committees, flexible and pragmatic government rules, and synchronization of the corporate CSR activities with the lead programmes of the Government of India. These reinforcements can go a long way in making the CSR approach much more effective and value accretive.

Studies have revealed how millennials use social networking sites (SNS) but users aged 50 years and above have not been studied by SNS researchers in India. This paper attempts to study the verbal claim and actual content created by Indians’ aged 50 years and above on Facebook (Facebook, hereafter referred to as the “Social Media” or “SM”, is restricted by the Russian media regulator Roskomnadzor) using a comparative research design. The study was carried out by selecting one hundred profiles of Monthly Active Users (MAU) of Social Media (SM) qualifying the age criteria. Empirical evidence for comparison was drawn by conducting: a. guided telephonic interview to know MAU’s claimed SM usage and b. quantitative content analysis to identify MAU’s actual SM activity. The results show that the participant’s claims of their SM activity do not support their actual usage of the platform. The variables studied and compared include the ‘source’, ‘context’ and ‘features used’ to write the content. Conclusions reveal the dilemmas and SNS usage related preferences of older age groups in India. The study highlights the need and scope for training the older generation(s) about using SNS. Such vocational training would help them conveniently adopt and use networked technologies for communication and recreational purposes.

Cr-Mo steels are well-known for their high temperature application in thermal power plants. P91, P911 and P92 are most commonly used Cr-Mo steels for high temperature application. The steels de-rived their strength from tempered martensite and precipitates of MX and M23C6 type. The normalizing and tempering of the steels are performed before putting them in service condition. The present manuscript describes the effect of the varying heat treatment regimes on microstructure and mechanical properties of the P92 steel. The normalizing effect on microstructure and mechanical properties has been studied. The normalizing was performed in the range of 950–1150 ºC. The effect of the varying tempering time on mechanical behavior of the P92 steel has also been studied and effort to develop relation between microstructure and mechanical properties was made. Optical microscope and scanning electron microscope have been utilized for microstructure study. To characterize the mechanical behavior, tensile, hardness and Charpy impact toughness tests were performed.

This study reports the common problems of weed species that adversely affect the crop productivity of the agriculture crops at a large scale. The purpose of this study is to investigate the impact of dried application of Chenopodium murale and Coronopus didymus on seed germination and early growth of Hordeum vulgare. The experiment was performed in a randomised block design with three replications under the greenhouse condition in pot culture. Shoots and roots materials were separately dried in shade for 15–20 days, dry powdered shoot and root residues of C. murale and C. didymus were applied at 5 and 10g kg-1 doses to barley seeds in 6” pots with control for three weeks. C. didymus (10g) shoot residues were most inhibitive against germination (31.16%), GVI (0.85), SVI (4.90) and leaf area (3.94 cm2) of barley while 5 g root residues of the weed had least pronounced effect. Root length, shoot length, and dry biomass were most inhibited by C. murale 10 g in both shoot and root residue treatments. Shoot residues were more inhibitive of germination and growth than root residues of both weeds. Chlorophyll accumulation patterns showed mixed results with some treatments even stimulating their concentrations. Root treatments were in general more inhibitive than shoot treatments. All treated seedlings exhibited higher levels of proline accumulation compared to control. At lower dose, C. murale treatments were more inhibitive than C. didymus treatments. There is a great scope of research on these species to isolate and identify the active factors and also to understand their implication in the biocontrol of weeds apart from their potential negative effects on agricultural crops, especially cereal crops, which can be useful to increasing crop production in northern India, namely in Uttar Pradesh

The major population of the world is dependent on rice for food. Global warming creates drought conditions mostly in north eastern countries. It is a very challenging task to cultivate drought-sensitive variety in drought-prone areas. To overcome this problem we induced changes in the drought-sensitive variety of rice (Swarna MTU 7029) for drought tolerance. Drought condition was exposed for 7 days and 14 days to SA treated and untreated 56 days old rice plants. Rice seeds were presoaked with 0.5mM SA. The experiment was designed in four groups control (untreated), drought -SA, drought +SA, and SA control. On the 7th and 14th of drought stress, SA improved drought tolerance indicator proline, carotenoid, and total soluble sugar. Starch and protein content were augmented in salicylic acid-treated plants compared to untreated rice plants under drought stress. Antioxidants such as SOD, CAT, and APX levels drastically increased in salicylic acid-treated plants during both 7th and 14th days of drought stress. Therefore, salicylic acid improved antioxidative enzymes content in MTU 7029 rice variety after 7 and 14 days of drought stress.

The saving and investment pattern of different forms sample group was studied during 2014-16 and it was observed that large farm holders were able to save higher income than small farmers while lowest income group had negative savings. In respect of investment on different fixed assets, irrigation was on first priority, followed by purchase of milch animals, farms buildings and investment in land and its improvement. Investment on working capital amongst different cash inputs, hired human labourer accounted highest share (29.44 per cent), followed by manure & fertilizers (22.33 per cent), hired power tractor (16.96 per cent), irrigation (13.61 per cent) and seeds (13.50 per cent) to total cash inputs. Marginal farmers could not invest for nonfarm physical capital because of no savings with them. Small and large farmers groups invested in all the items in which it was highest in working capital (61.28 to 61.84 per cent), followed by investment in fixed capital (14.41 to 16.84 per cent), financial capital (12-14 per cent) and non-farm capital (7-12 per cent). The highest investment was made on working capital (69.02 per cent) by sample farmers. Current income was found to be the main source of finance in all income groups which accounted for 49.70 to 94.79 per cent share of the total investment followed by savings which shared for 40.10 to 49.12 per cent in total investment.

This study introduces a new modified Moore – Gibson – Thompson Photo-Thermal (MGTPT) theory with two temperatures for semiconductor material. The photo-thermoelastic effects has been investigated in an infinitely constrained semiconducting solid cylinder subjected to variable heat flux in the form of exponential laser pulse. The Laplace transforms were used for the solution of the mathematical model in the transformed domain. The numerical inversion was applied to obtain the displacement components, the conductive temperature, the carrier density, and the thermal stresses in the physical domain. The impact of different theories of thermoelasticity with two temperatures on the displacement, temperature, thermal stresses and carrier density were represented graphically and discussed using Matlab software.

Aim: Variations in cone tip diameter while obturation can lead to premature binding, extrusion, or poor adaptability of GP to the canal walls and promotes microleakage and ultimately endodontic failure. The purpose of this investigation was to measure the variability from the listed cone tip diameter and taper of size #25, 0.06 taper GP cones from three different brands with the help of stereomicroscope and digital micrometer.Materials and methods: 45 GP points (N = 45) of Size #25 with an 0.06 taper from three different brands were divided into three groups: Group A – Diadent Group B – K3 and Group C Pro- Taper Next. Each group have 15 GP (n = 15). The diameters (D0 and D3), tapers were measured according to the ANSI/ADA Specification No. 78 using stereomicroscope (accuracy of 0.001mm) and digital micrometer. Kruskall Wallis test was to detect any significant differences between two or more groups and Mann Whitney U test for pairwise comparison. p value < 0.05 were considered as statistically significant.Results: On comparing there was significant variability within the three brands using stereomicroscopy, the standard values for D0 diameter which was 0.25 ± 0.23, Protaper Next GP cones was the similar to the standardized values compared to Diadent and K3 GP cones which were significantly different from the standard values. On comparing diameter variation at D3, Protaper Next, 0.043 ± 0.018 was once again similar to its manufacturer standard values of 0.43 ± 0.022. Diadent showed mild variation with D3 Diameter of 0.44 ± 0.017 and K3 was significantly different from the standard values K3 was 0.41 ± 0.018.Conclusions: The results of the current study indicate significant variability between GP cone brands for both diameter and taper. However, the high standard deviation values associated with most of the diameter and taper differences from manufacturer’s nominal values also suggests high variability within individual brands.

There has been an expanding interest for eco friendly synthesis of silver nanoparticles that don't have so much toxic impacts on crops. Silver nanoparticles have a wide scope of utilizations, for example, catalysis, hardware, photonics, optoelectronics, detecting, agriculture and drugs. In this study, the biologically synthesized and characterization of silver nanoparticles have become the prime areas. Green synthesis of nanoparticles using plant extracts is being explored globally owing to the absence of disadvantages associated with conventional methods. This study reports the synthesis of silver nanoparticles using the extract of Bambusa vulgaris (Bamboo), Azadirachta indica (Neem) leaves, characterization of the synthesized by using techniques such as Ultraviolet-Visible (UV-Vis) spectroscopy confirmed the synthesis of nanoparticles, Fourier Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM) and EDX studies revealed the characteristics of the nanoparticles synthesized. Also under this, we examined the effects of silver nanoparticles (AgNPs) on pea plants in the terms of silver accumulation, production of reactive oxygen species (ROS), Quantification of Cell Death under ex situ conditions.

The population is increasing day by day and agricultural land is occupied by urban cities because of the shortage of residential areas and by increasing the industries the pollution is at peak level that causes climate change and uses of chemical fertilizers the soil fertility is decreased. Due to these environmental conditions the overall yield of cereals crops is reduced. The wheat is a major food source for all over the world. But the production of wheat nowadays is more far from the requirement. After the availability of whole genome sequence of bread wheat opens many new opportunities for scientists. This whole genome helps in deep analysis and to formulate new breeding technology and to develop an advanced variety of bread wheat that fulfills the need of requirement. The environment conditions (abiotic and biotic stresses) have a severe impact on wheat growth and development that reduces the overall yield. In winter wheat the cold stress causes delay in the fruiting process and break in growth. After the availability of the whole genome of wheat the deep analysis showed the presence of some frost tolerance genes. The over expression of these genes in Arabidopsis showed the increase in frost tolerance. This deep analysis helps breeders to come up with more stress tolerance variety. It also helps in finding new molecular markers that help in marker assisted breeding and in speed breeding. The advancement of Genomic and Proteomic drive the crop biotechnology to resolve the shortage of food for a large population.

The nuclear radius parameter of carbon, aluminium, iron, copper, and zinc nuclei has been determined by using (n,γ)-reaction. The neutrons from the americium-beryllium source are made to interact with the water moderator to produce the γ-rays of 2.2 MeV through (n,γ)-reaction. The γ-radiation emitted from the water medium is measured with a scintillation detector coupled to 8k multi-channel analyzer. The neutrons from the americium-beryllium source are allowed to transmit through carbon, aluminium, iron, copper, and zinc elemental targets of various thicknesses, and transmitted neutrons are again allowed to interact with water moderators to produce 2.2 MeV γ-radiation. By measuring the yield of γ-radiation produced in water moderators by neutrons transmitted through elemental targets of different mass number values, the total neutron interaction cross-sections are determined. By knowing the total neutron interaction cross-sections and mass number of the target nuclei, the radius parameter has been determined.

The dielectric interpretation of crystal ionicity evolved by Phillips and Van Vechten (P.V.V) has been utilized to evaluate various ground state properties for broad range of semiconductors and insulators. Although, the relevance of P.V.V dielectric theory has been restricted to only simple ANB8-N structured compounds, which have a particular bond. Levine has broadened P.V.V. theory of ionicity to multiple bond and complex crystals and evaluated many bond parameters for ternary tetrahedral semiconductors. Some other researchers have extended Levine’s work with a concept of ionic charge product and nearest neighbour distance to binary and ternary tetrahedral crystals to evaluate the ground state properties. In this paper, a new hypothesis of average atomic number of the elements in a compound has been used to understand the some electronic and optical properties such as ionic gap (Ec), average energy gap (Eg), crystal ionicity (fi), electronic susceptibility (χ), and dielectric constant (ϵ) of ternary tetrahedral (AIIBIV and AIBIII) semiconductors. A reasonably acceptable agreement has been noticed between our evaluated values and other researchers reported values.

The concept of ionicity has been developed by Phillips and Van Vechten from the dielectric analysis of the semiconductors and insulators to evaluate various bond parameters of binary tetrahedral (AIIBVI and AIIIBV) semiconductors. In this paper, an advance hypothesis of average atomic number of the elements in a compound has been used to evaluate intrinsic electronic and optical parameters such as ionic gap (Ec), average energy gap (Eg), crystal ionicity (fi) and dielectric constant (ϵ) of binary tetrahedral semiconductors.

G-Coat Plus is a nano-filled, self-adhesive light cured protective coating that strengthens, protects and enhances glass ionomer restorations. The effect of G- Coat plus on different GICs have not been studied comprehensively. Hence the study was conducted to compare the effect of resin coating on surface hardness and Shear punch strength of newer modified GIC.Materials and methods: 120 samples of three GICs i.e. Fuji IX Extra, Fuji IX Fast, Fuji II LC were prepared using specialized metal moulds. Specimens of Fuji II LC were light cured for 20 seconds. Coated and uncoated samples were tested for surface hardness and 30 samples were tested for shear punch strength. P < 0.05 was considered as significant. Results: Shear Punch Strength after G-Coat plus coating was significantly higher for Fuji IX Extra followed by Fuji II LC. Surface Hardness after G- Coat plus coating was significantly higher for Fuji IX Extra followed by Fuji IX Fast and Fuji II LC.Conclusion: Surface coating by a resin agent significantly increases the surface hardness and shear strength of the GIC. Considering the above stated findings, they can be incorporated into daily clinical practice to enhance the strength and longevity of GIC.