1. [Structure and function of hepatocyte lysosomes and peroxisomes of rachitic rats].
- Author
-
Khomutovskiĭ OA, Mironova VN, and Degtiareva II
- Subjects
- Acid Phosphatase metabolism, Animals, Catalase metabolism, Histocytochemistry, Lysosomes enzymology, Microbodies enzymology, Microscopy, Electron, Rats, Rickets enzymology, Lysosomes ultrastructure, Microbodies ultrastructure, Organoids ultrastructure, Rickets pathology
- Abstract
The submicroscopic organization and activity of acid phosphatase and catalase in lysosomes and peroxisomes of the rat hepatocytes were studied with experimental rachitis. It is determined that total and free activity of acid phosphatase in the liver tissue and certain lysosomes with rachitis increases whereas the catalase activity in the tissue and certain peroxisomes decreases. Permeability of the lysosome and peroxisome membranes rises for enzymes and cations. The process of peroxisome differentiation with rachitis is disturbed: there appear peroxisomes containing the marginal plates, that is not peculiar to the redont peroxisomes.
- Published
- 1976