1. [A clinico-experimental study of patients with mycosis fungoides and Kaposi's sarcoma].
- Author
-
Faradzhev ZG, Parfenova TM, Shevliagin VIa, and Bykovskiĭ AF
- Subjects
- Adolescent, Adult, Aged, Cell Line, Chronic Disease, Female, Humans, Male, Microscopy, Electron, Middle Aged, Mycosis Fungoides microbiology, Retroviridae ultrastructure, Sarcoma, Kaposi microbiology, Skin Neoplasms microbiology, Tumor Cells, Cultured microbiology, Tumor Cells, Cultured pathology, Mycosis Fungoides pathology, Sarcoma, Kaposi pathology, Skin Neoplasms pathology
- Abstract
Twenty-six cultures were prepared by the cultivation method. Continuous cells lines (IK-10 and IK-12) were obtained in two cases, in the rest short-lived cell cultures were prepared. All the isolated cell cultures were studied by transmission electron microscopy. Abnormal lymphoblasts were detected in some cell cultures isolated from the blood and lymph nodes of mycosis fungoides (IJ-137, IK-140, IK-142, IK-143) and Kaposi's sarcoma patients (IK-145). Cell population consisted of small, medium, and large lymphocytes. Electron microscopic examination has revealed retroviruses in IK-143 culture, isolated from the lymph node of a patient with mycosis fungoides. Morphologically these particles were typical of type C oncoviruses, 120-140 nm in diameter, with a spherical core in the center of the virion.
- Published
- 1990