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Your search keyword '"Nerve Sheath Neoplasms chemistry"' showing total 2 results
Start Over Descriptor "Nerve Sheath Neoplasms chemistry" Language russian
2 results on '"Nerve Sheath Neoplasms chemistry"'

1. [Morphologic and differential diagnosis of sclerosing perineurioma].

Author

Shelekhova KV, Kazakov DV, Matsko DE, and Mikhal M

Subjects
Adult, Antiporters analysis, Biomarkers analysis, Diagnosis, Differential, Female, Humans, Immunohistochemistry, Keratins analysis, Male, Middle Aged, Nerve Sheath Neoplasms chemistry, Peripheral Nervous System Neoplasms chemistry, S100 Proteins analysis, Sclerosis diagnosis, Biomarkers, Tumor analysis, Nerve Sheath Neoplasms pathology, Peripheral Nervous System Neoplasms pathology
Abstract

The paper discusses morphologic and immunohistochemical characteristics of sclerosing perineurioma. Generally, it is well circumscribed and consists of tiny spindle-shaped plump epitheloid cells embedded in collagenous hyalinized matrix. Immunohistochemically, it was represented by EMA+, S-100, AE1/AE3, CAM 5.2, smooth muscle actin and desmin. Being benign, tumor was identified by differential diagnosis using fibroma of tendon sheath, sclerosing one, glomal tumor, giant cell tumor and sclerosing epitheloid cell sarcoma.

Published
2009

2. [Malignant neoplasms of the peripheral nerve sheaths with cellular immunophenotype of perineural cells (perineural sarcoma?)].

Author

Smirtnov AV and Sokolova IN

Subjects
Adult, Antibodies, Monoclonal, Diagnosis, Differential, Female, Humans, Immunohistochemistry, Immunophenotyping, Male, Microscopy, Electron, Neoplasm Proteins analysis, Nerve Sheath Neoplasms chemistry, Nerve Sheath Neoplasms ultrastructure, Nerve Tissue Proteins analysis, Neurilemmoma pathology, Neurofibrosarcoma chemistry, Neurofibrosarcoma ultrastructure, Peripheral Nervous System Neoplasms chemistry, Peripheral Nervous System Neoplasms ultrastructure, Sarcoma chemistry, Sarcoma ultrastructure, Soft Tissue Neoplasms chemistry, Soft Tissue Neoplasms ultrastructure, Nerve Sheath Neoplasms pathology, Neurofibrosarcoma pathology, Peripheral Nervous System Neoplasms pathology, Sarcoma pathology, Soft Tissue Neoplasms pathology
Abstract

2 cases of soft tissue malignant tumors formally related to the group of spindle cell sarcoma are described. The majority of cells expressed an epithelial membranous antigen and vimentin but were S-100 protein unreactive, i.e. had a phenotype characteristic of perineural cells. Monoclonal antibodies to 5 types of filaments protein of intermediate type, neurone specific enolase and collagen type I, II, III, IV, V were also used as well as electron microscopic investigation. Problems of differential diagnosis from schwannomas, fibrosarcomas, monophasic spindle cell "synovial sarcoma" and validity of integrating these tumors into an independent variety of malignant peripheral nerve sheath tumors are discussed.

Published
1995

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