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Three-day rat pups were X-irradiated (5 Gy) and killed on days 3-4, 6-7, and 10-11. Using the microscopic, histological and morphometric methods it was found that the microcirculation channel was damaged to a greater extent than the hemocirculation one. This was followed up during the radiation sickness. The pathological changes were more pronounced in all structures of the derma papillary layer than in those of the reticular layer. Oedema and reduced cellularity were noted in the connective frame.

Albino female rats were exposed to X radiation (5 Gy, 180 kV, 10 mA, filter 0.5 mm Cu) on days 10-15 of pregnancy. After 3 and 7 days they were sacrificed (under ether anesthesia) and fetuses were extracted. The status of the lympho- and hemomicrocirculatory beds (LMCB and HMCB) of the fetus back skin was studied by the macro- and microscopic methods. As early as day 3 of radiation sickness the diameter of LMCB vessels increased by 1.4-1.9 times, whereas changes in GMCB were less pronounced. On day 7, there was a progressive increase in dilatation of LMCB vessels, alongside with the narrowing of large units (arteries and veins). The development of the connective framework of the fetus skin was retarded.

Morphofunctional state of the lymphatic bed of the conjunctiva has been studied under effect of ultraviolet radiation. A comparative characteristics of development of the clinical picture and morphological criteria of the harmful effect of the ultraviolet radiation is presented. When all clinical symptoms disappear, there is no complete restoration of the capacitance function of the lymphatic vessels and intracellular regeneration of ultra-microscopical structures of endotheliocytes.

The article deals with the results of ultrasonic examination (USE) of 39 patients with secondary edema of the lower extremities. The authors developed a USE method which yields objective data characterizing changes of the structure, thickness, boundaries, and firmness of the soft tissues in lymphedema of the lower extremities of various severity. It was established that lymphostasis produced a characteristic ultrasonic pattern, which, as claimed by the author, may be used in differential diagnosis of lymphatic and venous edema of the extremities.

Pronounced morphological alterations combined with destruction of muscular tissue make their appearance in intact arterial and lymphatic bed of pelvic extremities in rats after treatment with ultrasound of high intensity. Ultrasound of low intensity failed to cause morphological changes either in the arterial or the lymphatic bed of extremities. A course of exposure of injured arterial and lymphatic bed of rat's pelvic extremities to ultrasound of small intensity considerably accelerated processes of formation of the arterial and lymphatic collaterals.

The mechanism of action of helium-neon laser stimulation has been studied in 26 eyes of 15 patients with dystrophic diseases of the eye and on the ground of 63 lymphangiographic investigations of the same patients. It was found that low-energy helium-neon laser stimulation (0.05-0.5 mWt/cm2) has a positive effect on restoration of visual functions. Lymphangiographic investigations have revealed a new biological phenomenon--activation of disturbed lymphatic flow under the action of a specially organized laser radiation. The results obtained confirm the earlier hypothesis (M. M. Krasnov et al., 1982) that under the action of laser radiation a normal physiologic system purifying the retina from disintegrated products is engaged into action.

In experiments on mice CBA the activity of spleen lymphocytes was investigated in sham-operated mice and in mice with denervation-delymphatization of the both kidneys. The activity of lymphocytes was determined by registration of amounts of colony-formed elements by the method of Till and McCulloch. Periodic increase of the lymphocytes activity has been observed in mice with denervation-delymphatization kidneys. It is supposed that the periodic activation of lymphoid system, induced by denervation-delymphatization, may be one of triggering mechanisms of transplant rejection.

The paper is concerned with the results of experimental dosimetric studies on an anthropomorphic phantom using thermoluminescent dosimetry at the site of the joining of large fields of complex shape simulating total irradiation of the lymphatic collectors. The studies demonstrated the appropriateness of the joining at a distance of 1 cm between the fields. In such a variant adequate irradiation of the lymphatic system was achieved whereas an increase in a distance between the fields resulted in a risk of recurrence in under-irradiated areas without a significant decrease in radiation dose exposure to healthy organs and tissues.

The effectiveness of prophylactic irradiation of areas of the neck commonly involved in metastatic spread was studied in 276 patients with nasopharyngeal malignancies who were followed up during 5 and more years. The analysis was carried using such criteria as the decrease in the frequency of recurrent regional metastases, distant metastases and increase in 5-year survival. The absorbed doses ranged 45-50 Gy. The procedure was followed by a decrease in the frequency of regional metastases (3.4% versus 32.7% in untreated patients). The frequency of distant metastases decreased nearly by half (19.5% versus 31.7%). Five-year survival rates increased significantly from 49 to 65.5%. This relationship was recorded for all histological types of tumors. Application of prophylactic irradiation in doses of 45-50 Gy prevents local subclinical metastasis development in most patients.

The work performed in 48 experimental and 24 control rats dealt with the development of arterial and lymphatic collaterals of pelvic extremities under effects of magnetic field of ultra high frequency (15 and 30 vt) in terms from 2 up to 6 weeks after surgery and exposure to magnetic field. The methods of investigation were arterio- and lymphoroentgenography and dissection. It has been established that formation of arterial collaterals in experimental rats takes place in all zones during the second week after cutting femoral arteries. The rate of the development of arterial collaterals was accelerated as compared with control animals. The lymph outflow after exposure to the influence of magnetic field of UHF goes mainly along superficial collaterals to groin nodes. The influence of the magnetic field of UHF appears to be accompanied by stable dilatation of super ficial lymph vessels, and due to this the lymph outflows along these vessels.

Total mesentery preparations of the rat after single total irradiation at the dose levels of 15 and 30 Gy were examined by V. V. Kupriyanov 's method and staining by N.E. Yarigin and S.V. Panchenko . Monotonous pathomorphological changes characteristic of microcirculation disorders were revealed such as blood overdistribution into the venous part of microvasculature prestasis , stasis and lymphostasis. Apart from these qualitative alterations, morphometry of certain parts of microvasculature was performed and some indexes and ratios were calculated. Changes of quantitative parameters were as follows: increase of the capillaries, postcapillaries and venules diameter, increase of their surface and volume, increase of diameter of pericapillary diffusion zone; decrease of the correlation ratio between total arteriolar influx and total venular blood passage within a mesentery segment; decrease of the calculated linear speed of blood in capillaries, postcapillaries and venulas .