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Objectives. To analyze the main age-specific data of the incidence of malignant neoplasms of the larynx in the Republic of Belarus during 2000-2019. Material and methods. The age indicators of the incidence were compared for the entire population and differentiated by sex and area of residence in 2000-2004 and 2015-2019. The distribution according to the stages was studied during 2000-2019 for the entire population and differentiated by sex and area of residence, as well as separately for people of working age. Results. The highest incidence was observed in age groups from 55 to 74 years for the entire population both in 2000-2004 and in 2015-2019. The peak incidence was noted in the age groups from 60 to 64 years both in 2015-2019 (23.3 per 100,000) and in 2000-2004 (19.8 per 100,000). The increase of the incidence occurred in the age groups 55 years and older. The largest increase of the incidence was 1.3 in the group of people aged 60-64 years in 2015-2019 compared to 2000-2004. The growth rate was more pronounced among rural residents in comparison with the urban ones. The average age of patients in 2000-2004 was 60.1 years, whereas in 2015-2019 it was 61.2 years. The average proportion of cases of malignant larynx neoplasms diagnosed at stages I-II made up 46% with some regional fluctuations. Conclusions. The age-specific distribution of the incidence of malignant neoplasms of the larynx in the Republic of Belarus did not undergo any significant changes during 2000-2019. The highest incidence rates were noted in the age groups from 55 to 74 years. An increase of the incidence was noted in people aged 55 and over. The proportion of cases of malignant neoplasms of the larynx of stage III-IV exceeded that of cases of stage I-II throughout the whole study period.