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Aim: A comparative analysis of the psycho-emotional status and quality of life of patients with acne and post-acne., Material and Methods: There were 147 patients included in the study, 84 (57%) women and 63 (43%) men, aged from 14 to 48 years. The following parameters were studied: CADI score, APSEA score, DLQI score. Anxiety and depression were assessed with HAM-D and HAM-A., Results: Higher scores on CADI, APSEA and DLQI and dissatisfaction with the results of therapy were noted in older patients. Significant changes in CADI, APSEA and DLQI scores in patients with post-acne symptoms were recorded later compared to patients with acne. Anxiety and depression symptoms measured with HAM-D and HAM-A reached the level of depressive disorder of moderate severity and moderate anxiety in patients over 20 years old. Mental disorders were qualified within the nosogenic anxiety-phobic reactions developing in connection with dermatosis manifestation., Conclusion: Acnes substantially better give in to correction than post-acne symptom complex. Regardless of age, post-acne symptoms considerably reduce quality of life of patients, sometimes causing more expressed changes (anxiety and depression) than dermatosis.