1. [Effect of medium viscosity on the activity of myosin ATPase].
- Author
-
Khoshtariia DE and Goguadze NG
- Subjects
- Adenosine Triphosphate metabolism, Animals, Hydrolysis, In Vitro Techniques, Kinetics, Muscles enzymology, Protein Conformation, Rabbits, Solutions, Viscosity, Adenosine Triphosphatases metabolism
- Abstract
The influence of increased medium viscosity on the activity of myosin Ca2+-ATPase has been studied in 28, 45 and 60% water-sucrose solutions at 25 degrees C. In the wide range of viscosities (10 divided by 430 mp) the rate constant of ATP hydrolysis displays the negative power-law dependence on solution viscosity with an index approximately -0,5. The obtained data confirm an idea about the existence of direct connection between the low-frequency liquid relaxations and structural dynamics of proteins and enzymes.
- Published
- 1986