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Your search keyword '"Ethionine pharmacology"' showing total 21 results
Start Over Descriptor "Ethionine pharmacology" Language russian
21 results on '"Ethionine pharmacology"'

1. [Effect of methylation antagonists on biosynthesis of tetrapyrrole compounds by Propionibacterium shermanii].

Author

Bykhovskiĭ VIa, Zaĭtseva NI, Andreeva NA, and Iavorskaia AN

Subjects
Aminopterin pharmacology, Ethionine pharmacology, Folic Acid Antagonists, Methotrexate pharmacology, Methylation, Propionibacterium drug effects, S-Adenosylhomocysteine pharmacology, Porphyrins biosynthesis, Propionibacterium metabolism, Vitamin B 12 biosynthesis
Abstract

The effect of methylation antagonists (DL-ethionine, S-adenosyl homocysteine and folic acid analogs-aminopterine, ametopterine and tomisine) on vitamin B12 and porphyrin biosynthesis of P. shermanii resting cells was studied. DL-ethionine proved the most active inhibitor. Inhibition of vitamin B12 biosynthesis induced by DL-ethionine was accompanied by increase in porphyrin formation. DL-methionine reversed the inhibitory effect of DL-ethionine on the vitamin synthesis. Other compounds tested showed a less marked effect.

Published
1980

2. [Effect of ethionine on intestinal enzymatic activity in adult rats].

Author

Kadyrov UZ, Rianskaia OM, Dzhamilova NM, and Shigapova SR

Subjects
Amylases metabolism, Animals, Dipeptidases metabolism, Enzyme Activation drug effects, Glycine analogs & derivatives, Glycine metabolism, Glycoside Hydrolases metabolism, Intestinal Mucosa drug effects, Intestinal Mucosa enzymology, Intestines drug effects, Male, Monoacylglycerol Lipases metabolism, Rats, Sucrase metabolism, Time Factors, beta-Fructofuranosidase, Ethionine pharmacology, Intestines enzymology
Abstract

The activity of intestinal enzymes (dipeptidase, monoglyceride lipase, amylase, invertase) was studied in intestinal mucosa homogenates from different parts of the small intestine in adult rats 24, 48, and 72 hours after a single intraperitoneal administration of ethionine in a dose of 500 mg/kg bw. 24 hours after antimetabolite administration there was a decrease in the abrasion of the small intestinal mucosa. The enzyme-forming function of the small intestine appreciably changed throughout the observation period. The activity of invertase, dipeptidase and amylase decreased. The monoglyceride lipase activity remained unchanged. The pattern of amylase and invertase distribution in the small intestine changed at the expense of inhibition of their activity in the duodenum and rise in the distal part.

Published
1981

3. [Effect of protein synthesis inhibitors on the hormonal induction of alanine and aspartate aminotransferases in the liver of sexually mature male rats].

Author

Polikarpova LI

Subjects
Alanine Transaminase antagonists & inhibitors, Animals, Aspartate Aminotransferases antagonists & inhibitors, Dactinomycin pharmacology, Depression, Chemical, Drug Interactions, Enzyme Induction drug effects, Ethionine pharmacology, Hydrocortisone pharmacology, Injections, Intramuscular, Injections, Intraperitoneal, Insulin, Long-Acting pharmacology, Liver drug effects, Liver enzymology, Male, Protein Biosynthesis drug effects, Puromycin pharmacology, Rats, Stimulation, Chemical, Time Factors, Alanine Transaminase metabolism, Aspartate Aminotransferases metabolism, Proteins antagonists & inhibitors
Published
1974

4. [Effect of actinomycin D and ethionine on hormonal induction of ribonucleic acid synthesis in the nuclei and cytoplasm of the liver cells of adult male rats].

Author

Ponomarev VI

Subjects
Animals, Cell Nucleus metabolism, Hydrocortisone pharmacology, Insulin, Long-Acting pharmacology, Male, RNA, Ribosomal biosynthesis, Rats, Transcription, Genetic drug effects, Dactinomycin pharmacology, Ethionine pharmacology, Liver metabolism, RNA biosynthesis
Abstract

Ethionine did not affect but actinomycin D inhibited the increase in DNA-like RNA synthesis (precursor of ribosomal RNA in nuclei and rRNA in cytoplasm of liver tissue cells of adult male rats), which was caused by single administration of hydrocortisone or protamine-Zn-insulin and by both hormones. The data obtained suggest that the effect of these hormones on the synthesis of DNA-like RNA was realized at the stage of transcription.

Published
1977

5. [Enzymatic function of the pancreas under the effect of anabolic preparations and diets with different amounts of protein].

Author

Narodetskaia RV, Nesterin MF, and Solov'eva GI

Subjects
Amylases metabolism, Animals, Diet, Diethylstilbestrol pharmacology, Ethionine pharmacology, Male, Methandrostenolone pharmacology, Organ Size, Pancreas drug effects, Propionates pharmacology, Rats, Testosterone pharmacology, Trypsin metabolism, Trypsin Inhibitors metabolism, Anabolic Agents pharmacology, Dietary Proteins, Pancreas enzymology
Published
1974

6. [Increasing rat liver glutathione peroxidase and glutathione reductase activity by administering phenobarbital].

Author

Panchenko LF, Gerasimov AM, Koen IaM, and Koroleva LA

Subjects
Age Factors, Animals, Dactinomycin pharmacology, Drug Interactions, Enzyme Activation drug effects, Ethionine pharmacology, Liver enzymology, Male, Rats, Seasons, Time Factors, Glutathione Peroxidase metabolism, Glutathione Reductase metabolism, Liver drug effects, Peroxidases metabolism, Phenobarbital pharmacology
Published
1975

8. [Effect of inhibitors on the soluble summary protein complex and isoenzymes of Chlorella].

Author

Pinevich VV, Bers EP, and Passkel' GG

Subjects
Acid Phosphatase metabolism, Alcohol Oxidoreductases metabolism, Alkaline Phosphatase metabolism, Chloramphenicol pharmacology, Chlorophyta drug effects, Dactinomycin pharmacology, Electrophoresis, Esterases metabolism, Glucosephosphate Dehydrogenase metabolism, Glutamate Dehydrogenase metabolism, Malate Dehydrogenase metabolism, Puromycin pharmacology, Anti-Bacterial Agents pharmacology, Azaguanine pharmacology, Chlorophyta metabolism, Ethionine pharmacology, Isoenzymes metabolism, Proteins metabolism
Published
1970

9. [Effect of ethionine on riboflavin metabolism].

Author

Cherkes LA, Ganetskaia SA, and Aptekar' SG

Subjects
Animals, Female, Liver drug effects, Liver metabolism, Male, Rats, Riboflavin urine, Ethionine pharmacology, Riboflavin metabolism
Published
1966

11. [The level of bilirubin and cholesterol in rat blood in acute fatty dystrophy (steatosis) and liver cirrhosis caused by prolonged choline deficiency and ethionine].

Author

Sergeeva KV

Subjects
Animal Feed, Animals, Choline pharmacology, Fatty Liver etiology, Liver Cirrhosis chemically induced, Liver Cirrhosis etiology, Methionine pharmacology, Rats, Stimulation, Chemical, Bilirubin blood, Cholesterol blood, Choline Deficiency blood, Ethionine pharmacology, Fatty Liver blood, Liver Cirrhosis blood
Published
1968

13. [Effect of phenobarbital and medinal on lysine incorporation in rat liver proteins in vitro].

Author

Mardashev SR, Voronov AIa, and Debov SS

Subjects
Adenine Nucleotides pharmacology, Animals, Carbon Isotopes, Cell-Free System, Dactinomycin pharmacology, Depression, Chemical, Ethionine pharmacology, In Vitro Techniques, Liver drug effects, Lysine metabolism, Phenobarbital antagonists & inhibitors, RNA biosynthesis, Rats, Stimulation, Chemical, Barbiturates pharmacology, Liver metabolism, Microsomes metabolism, Phenobarbital pharmacology, Protein Biosynthesis
Published
1967

14. [Experimental acute pancreatitis].

Author

Synovets AS, Levitskiĭ AP, and Michurin VF

Subjects
Acute Disease, Animals, Common Bile Duct, Disease Models, Animal, Dogs, Endopeptidases pharmacology, Ethionine pharmacology, Ligation, Methods, Pancreas drug effects, Pancreas enzymology, Pancreas injuries, Pancreatic Ducts, Rabbits, Rats, Sodium pharmacology, Taurocholic Acid pharmacology, Trypsin pharmacology, Pancreatitis
Published
1973

18. [Effect of inhibitors of nucleinic, protein synthesis and cell division on primary immunologic response].

Author

Uteshev BS, Pinegin BV, Babichev VA, and Levashev VS

Subjects
Animals, Antibody-Producing Cells drug effects, Chloramphenicol pharmacology, Colchicine pharmacology, Depression, Chemical, Ethionine pharmacology, Flavonoids pharmacology, Fluorouracil pharmacology, Methotrexate pharmacology, Mice, Spleen drug effects, Spleen immunology, Antibody Formation drug effects, DNA antagonists & inhibitors, RNA antagonists & inhibitors
Published
1970

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