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Introduction. Today, infertility is a global problem that affects about 48.5 million married couples worldwide. It has been suggested that epigenetic aberrations are of great importance for reproductive health, as they account for an interactive relationship between genomic landscape, interplay with gene environment and disease phenotype. A new understanding on etiology of complex non-Mendelian disease traits has aroused a growing interest in reproductive epigenetics.Aim: to analyze available publications on epigenetic aspects of male and female infertility as well as nutrition-related risk factors.Materials and Methods. There was conducted a search for publications in the electronic databases PubMed, Google Scholar and Library to be selected in accordance with PRISMA recommendations. All relevant articles published before November 2023 were included in this review. As a result of the search, there were extracted 530 publications from PubMed, 57 publications – from eLibrary and 23 publications – from Google Scholar. Duplicates and non-full-text article versions were excluded.Results. Environmental factors play an important role in generation and maintenance of epigenetic marks. DNA methylation abnormalities can lower human fertility. Altered protamine level may affect epigenetic paternally transmitted DNA information. Long-term infertility is associated with a modified methylome in euploid blastocysts primarily affecting regulation of genomic imprinting. Both excess and deficiency of trace elements are associated with adverse pregnancy outcomes, similarly applied infertility.Conclusion. Despite that epigenetic mechanisms, genes, nutrition and dietary supplements discussed here affect infertility, while a relevant recommended dose has not yet been determined, it was noted that such parameters may positively influence fertility. However, more comprehensive and longitudinal human studies are required to examine their relationship to male and female reproductive functions.

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Depression is one of the leading causes of disability worldwide. It affects, according to WHO, nearly 300 million people worldwide, a number close to 3,8 % of the world’s population. Depression is not exclusively a mental disorder limited to psychiatry, nowadays it is present in all medical fields. It has a significant association with many comorbidities, as an example cardiovascular diseases and metabolic disorders. Additionally, depression often is manifested with psychosomatic symptoms. Both aspects lead clinicians to major diagnostic and therapeutic challenges. Each one of dietary element: omega-3 fatty acids, zinc, selenium, iron, vitamin B12, vitamin D, folate, creatine was found to correspond with mental health in patients and the level of mentioned diet components is negatively correlated with depression risk of individuals. Each of the dietary aspect considered in the article has a significant correlation with depression disorder and might support the new multidisciplinary attitude toward it in mental health.

Breast cancer is the most common malignancy among women. We conducted an analysis to investigate the impact of diet on breast cancer. Well-balanced diet is a mandatory part of a healthy lifestyle, and consequently, it is very important in prevention of breast cancer. High intake of fruits and vegetables, proper BMI and low intake of alcohol and fried food rich in saturated fatty acids are common known to be anti-cancer prevention. Soy food, black pepper and turmeric are suggested to inhibit cancer’s proliferation. Dietitians and oncologists should educate their patients about healthy lifestyle patterns.

Objective to study the adherence to the principles of rational nutrition by representatives of various professional groups living in the Russian Federation and the Republic of Tajikistan. Material and methods.The study was conducted using a questionnaire-survey method among 543 mental workers of the Samara region and 158 students of the Avicenna Tajik State Medical University (Republic of Tajikistan), followed by statistical processing of the data. Results.Violations of the principles of rational nutrition are commonin various professional groups of the working-age population, including among students of a medical university. According to anthropometric studies, 61% of the surveyed workers were overweight and obese; in the group of students this indicator was only 8%, 29% of students were underweight. Violations of nutrition regimen were found among 31.1% of employees and 38% of students. Factor analysis of the actual nutrition of workers revealed 5 types of nutrition models characterized by a stereotype of eating behavior due to the consumption of certain foods and beverage. The regression analysis confirmed the relationship between the risk of obesity and adherence to types 2, 4 and 5 of nutritional models; an individual's adherence to nutritional model type 3 reduced this risk. In the group of the surveyed, the deterioration of the diet quality was revealed due to the excessive consumption of high-calorie foods, "fast food", sweet carbonated drinks, as well as insufficient consumption of vegetables, fruits, fish. The correlation analysis established the relationship between the body mass index and complaints presented by the survey participants concerning the cardiovascular, digestive, endocrine and musculoskeletal systems. The study identified the most common alimentary-dependent pathologies among students such as gastritis, chronic pancreatitis, and chronic cholecystitis. Conclusion.The revealed violations of the principles of rational nutrition, the nutritional status, form the risks of development of the gastrointestinal tract diseases, metabolic disorders and cardiovascular pathology. The results obtained indicate the need of preventive measures in relation to the adherence to the principles of rational nutrition, creating awareness in various professional groups of the population, including students of medical universities in different states.

Aim. To compare dietary patterns of the Omsk region male and female representatives with and without abdominal obesity (AO).Material and methods. Wthin the second study of Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation (ESSE-RF2) using a representative sample of Omsk region population aged 25-64 years (n=1648), dietary habits, including 21 food groups, were assessed by the questionnaire method. Eating habits of Omsk region representatives with (n=936) and without AO (n=712) were compared.Results. Insufficient consumption of vegetables and fruits practically does not differ in those with or without AO. Depending on sex, insufficient fruit consumption is more typical for both men and women without AO. In addition, there is insignificant increase of fruit consumption in AO people, especially women (p=0,09). Both men (p=0,05) and women (p=0,045) are less likely to consume meat daily but more often consume fish weekly compared to those without AO. This mainly applies to women, because women with AO, in contrast to those without AO, are significantly less likely to consume insufficient amount of fish (p=0,0001). Compared to women with, men with AO significantly more often daily and weekly consume seafood (p=0,001). Daily milk consumption is much less common in individuals with AO, but only at the expense of men with AO (p=0,0001). Kefir and yogurt, on the contrary, are more often consumed in patients with AO both daily and weekly. Omsk people with AO are less likely to introduce yogurt into their daily diet, mainly at the expense of women with AO (p=0,02). Excessive consumption of pasta is more typical for persons without AO (p=0,0001), and by means of men (p=0,001). Omsk residents with AO more often exclude the sweets and confectionery from diet. In the daily diet, they are much less common in individuals with AO (p=0,0001), especially in men with AO (p=0,0001). The respondents with AO daily consume pickles 1,4 times more often compared with those without AO, and mainly by means of men (p=0,03).Conclusion. Presence of AO somewhat changed the dietary habits of Omsk residents. AO patients are less likely to consume pasta, sweets and confectionery products, but more likely to eat pickles and to add more salt to cooked food, which requires targeted preventive measures, taking into account the identified sex priorities, depending on AO presence.

Abdominal obesity (AO) is an alimentary-dependent risk factor, the development and prognosis of which is directly specified by eating habits.Aim. To study the associations of dietary patterns and AO among the adult Russian population.Material and methods. The analysis was carried out using representative samples of male and female population aged 25-64 years (n=19297; men, 7342; women, 11,955) from 13 Russian regions. The response was about 80%. Nutrition was assessed based on the prevalence of consumption of the main food groups forming the daily diet. Results are presented as odds ratios and 95% confidence intervals.Results. Men with AO, compared with men without AO, more often consume red meat and vegetables/fruits daily by 12% and 13%, respectively, as well as less often eat cereals and pasta, confectionery, sour cream, and cottage cheese by 17%, 24%, 14%, and 19%, respectively. In women with AO, compared to women without AO, there are more differences in the diet, as they more often daily consume red meat by 28%, fish and seafood by 26%, poultry by 23%, meat and sausages and fruits/vegetables by 14%, milk, kefir, yogurt by 11%, as well as less often — cereals and pasta, sweets, and sour cream by 11%, 14%, and 8%, respectively. In women with AO, the prevalence and amount of drinking beer and dry wines is lower, but they consume spirits more frequently (p=0,0001), but without significant differences in amount. Men with AO have a higher prevalence and amount of drinking dry and fortified wines, as well as strong alcoholic drinks. Men with AO drinks higher amount of beer. In addition, men with AO showed a positive association with alcohol consumption (χ=53,64, p

Aim. To study the associations of dietary patterns with HTN in the adult population.Material and methods. The analysis was carried out on the data of representative samples of male and female population from 13 regions of Russia. The age ranged from 25 to 64 years (n=19,520; men, 7329; women, 12191). The response rate was approximately 80%.Results. Men with blood pressure (BP) >140/90 mm Hg more often consume meat and sausage products (OR, 1,08 [95% CI, 1,02-1,16]; p=0,011), less often — fresh vegetables/fruits (0,94 [0.89-0.96]; p=0,028), dairy products: milk, kefir (0,92 [0,87-0,97]; p=0,0041), sour cream (0,90 [0,84-0,96]; p=0,0021), cottage cheese (0,92 [0,85-0,99]; p=0,034) and sweets (0,91 [0,86-0,96]; p=0,00071). Women with BP >140/90 mm Hg less often consume fresh vegetables/fruits (0,95 [0,90-0,99]; p=0,032), milk, kefir (0,95 [0,91-0,99]; p=0,040), cottage cheese (0,95 [0,90-0,99]; p=0,047), cheese (0,92 [0,88-0,97]; p=0,00083) and sweets (0,89 [0,850,93]; p

Non-alcoholic fatty liver disease (NAFLD) is considered to be metabolically determined and alimentary condition, one of the components of metabolic syndrome. Therefore, dietary patterns of patients with different clinical types of the disease are worth to be studied . The aim of the research was to study the dietary patterns in patients with NAFLD and with type 2 diabetes mellitus (T2DM) (group T2DM+) compared to the control group without T2DM (T2DM-). Material and methods . A retrospective analysis of the database (n=316) of patients with NA FLD, formed in the period from 202 1 to 2023, was carried out. A total of 79 sex- and agem atched pairs of T2D+ and T2D- pat ients were selected for the case-control study. Hepatic steatosis and fibrosis stage assessment was performed using vibration-controlled transient elastography (VCTE) with controlled attenuation parameter (CAP). Actual nutrition was evaluated using a semi-quantitative method of assessing consumption frequency during a personal interview. Consumption of 100 grouped food items was assessed. Blood parameters characterizing lipid and carbohydrate metabolism were assessed. Results . Among patients with T2DM+, patients with NASH (24.1 vs 8.9%, p=0.005) and patients with severe liver fibrosis F3-F4 (32.9 vs 10.1%, p<0.0001) were significantly more common. There were no differences between the T2DM+ and T2DM- groups in energy consumption (1969 [1492; 3098] vs 1870 [1380; 2593] kcal/day; p=0.4), proteins (90.5 [71.5; 130.3] vs 81.0 [59.4; 116.0] g/day; p=0.1), fats (83.0 [66.7; 144.9] vs 78.8 [59.2; 116.4] g/day; p=0.3), carbohydrates (220 [156; 312] vs 209 [155; 282] g/day; p=0.9). The study of dietary patterns revealed greater consumption of meat and meat products (1.23 [0.84; 1.73] vs 0.96 [0.71; 1.37] times a day, p=0.03), fish and seafood (0.37 [0.17; 0.89] vs 0.27 [0.13; 0.51] times a day, p=0.01) in T2DM+ group. It was found that in patients with T2DM the intake of calories and the following nutrients from meat and meat products was more, then without: energy (289.6 [174.9; 420.3] vs 191.9 [148.2; 336.5] kcal/day, p=0.006), proteins (25.8 [17.2; 36.5] vs 18.6 [12.6; 29.6] g/day, p=0.008) and fats (18.9 [10.8; 31.4] g/day vs 13.7 [10.3; 23.6] g/day, p=0.01). Similar data was obtained for fish and seafood, with energy (59.7 [28.3; 117.3] vs 45.2 [20.5; 70.1] kcal/day, p=0.03), proteins (8.1 [6.9; 16.8] vs 6.3 [6.7; 10.2] g/day, p=0.02) and fats (3.0 [1.5; 6.4] vs 1.9 [0.9; 3.8] g/day, p=0.01) consumed more in T2DM+ group. Conclusion . In the traditional analysis of actual nutrition in NAFLD patients with and without T2DM, no significant differences were found. However, the structure of the patients' diet differs significantly due to meat and meat products, fish and seafood. The identified differences may indicate the need to change dietary recommendations for patients with T2DM, and may also become the basis for the development of innovative food for special dietary uses aimed at improving the quality of nutrition of patients and, as a result, remission of the underlying disease., Competing Interests: The authors have no conflict of interest to declare., (Copyright© GEOTAR-Media Publishing Group.)

Malnutrition in the early stages of life cause hypomotilinemia and shape the epigenome, and does not change the genetic code. Increasing the frequency of non-communicable chronic diseases (NCDS) in the world associated with influence of external factors, including poor diet and obesity .Purpose. A comparative study of dietary patterns in countries with similar social conditions but with different frequency of breast cancer.Materials and methods. Data on incidence of breast cancer in 160 countries is selected from the database GLOBOCAN 2008. Levels of consumption of food and nutrients (53 species) for each country selected from the FAO database for 1990–2005 and 2003–2005 years. The power structure of countries were represented in the form of a total daily level of consumption (DLC) (g/person/day), and also in the form of blocks of products with common source of origin (g/person/day): animal products, grains, vegetables”, “fruit drinks”, “alcoholic beverages”; “nutrients of animal products” (%): energy, protein, fat; “full of nutrients” (%): carbohydrates, proteins, fats; energy (kcal/person/day), proteins and fats (g/person/day). Determined the percent contribution of each block in the structure of food in the total daily consumption of food and nutrients (DLC). In the comparative analysis used as a predictor of the metabolic syndrome: body mass index (BMI ≥ 25 kg/m2) and blood cholesterol (NF ≥ 50 mmol/l).Results. Under similar social and geographical conditions in countries with a high incidence of breast cancer part of the power Structure were represented: 36% of “animal products”, 37% “of grain and vegetables,” 14% “fruits and beverages”, 13% “alcoholic beverages”. In the Mediterranean countries with a low incidence of breast cancer: 28% of “animal products”, 55% “grain & vegetables 11% fruits & drink”, 5% “alcoholic beverages”. In countries with a high incidence of breast cancer Nutrients “animal products” in 1,5 times more than in the Mediterranean countries with a low incidence of breast cancer.Conclusions. The food pattern has modifying effects on the risk of breast cancer.

Assessment and interpreting of the energy expenditure (EE) in highly skilled athletes are important components of an effective training and performance prediction. Each component of EE (resting energy expenditure, thermic effect of food, and physical activity energy expenditure) is closely related to dietary patterns, the intensity and duration of physical activity, as well as a number of other factors that affect the functional state of athletes. Despite the importance of EE in the training process, coaches and athletes often do not take EE into account, which reduces the objectivity of assessing athletes' functional state. The purpose of this research was to summarize the recent information on the structure of EE and energy consumption in athletes. Material and methods . The search and analysis of publications was carried out using the PubMed, MEDLINE, Scopus, Web of Science, eLIBRARY databases, mainly for the last 10 years, using the search keywords: rest energy expenditure, thermic effect of food, physical activity energy expenditure, energy intake, total energy expenditure, athletes. Results . This overview includes information on the components of total energy expenditure, such as rest energy expenditure, thermic effect of food and physical activity energy expenditure, as well as generalized information on the factors affecting the variability of their values and methods for assessing one or another type of energy expenditure. International nutritional recommendations regarding the level of physical activity of athletes are systematized, as well as the advantages and disadvantages of methods for studying energy consumption and total energy expenditure are presented. Conclusion . Combined study of energy intake and energy expenditure will help athletes avoid the negative impact of energy deficiency on performance, and the correct construction of the training process with the maintenance of adequate energy consumption will have a positive impact on the performance and recovery processes after intensive physical exertion., Competing Interests: The authors declare no conflicts of interest., (Copyright© GEOTAR-Media Publishing Group.)

Aim: To assess efficacy of dietary patterns modification with the use of specialized food in patients with non-alcoholic steatohepatitis (NASH)., Materials and Methods: We developed new specialized food (SPP2) based on literature data on the role of dietary patterns in pathogenesis of NASH. It contained -3 PUFAs, soluble dietary fiber, phospholipids, -lipoic acid, coenzyme Q10, L-carnitine, complex of vitamins. Patients with NASH (per EASL guidelines), were invited to participate in the study and were randomly assigned to receive either isocaloric diet (ICD) alone (based on the results of indirect calorimetry Cosmed, Italy) or isocaloric diet with specialized food (2 portions of SPP2 a day), for 14 days. Repeated examinations of body composition with phase angle analysis (InBody, Republic of Korea) and blood chemistry were performed at baseline (BL) and after 14 days (EOT). The patients were advised to follow usual physical activity during the study. Non-parametric statistics was used to compare BL and EOT characteristics in the groups., Results: The groups did not differ by age, proportion of females, and baseline characteristics of body composition. Adherence to the diet was 87.5% in the ICD group and 88.2% in the ICD+SPP group (p=0.65). Compliance with the use of SPP was 100%. In the ICD+SPP group significant reduction of body weight was achieved (117.530.1 kg initially, vs 114.928.8 kg at EOT; p=0.007), whereas in the ICD group it was not statistically significant (106.722.1 kg at BL vs 104.016.8 kg at EOT, respectively; p=0.07). In contrast to the ICD group, in those who received ICD+SPP significant decrease in cholesterol (5.31.3 mmol/L at BL vs 4.61.3 mmol/L at EOT; p=0.003), LDL (3.71.0 mmol/L vs 3.31.0 mmol/L, respectively; p=0.009), alkaline phosphatase (132.699.1 vs 112.087.0 U/L; p=0.04), GGT (54.533.2 vs 37.519.7 U/L; p=0.04), insulin resistance index (6.13.2 vs 3.21.5, respectively; p=0.04) was detected., Conclusion: Modification of dietary patterns with the use of a specialized food in combination with low-calorie diet allows achieving significant reduction of weight and improve lipid and carbohydrate metabolism, reduce severity of cholestasis in patients with NASH.

Type 2 diabetes is a major, non-communicable disease, with increasing prevalence worldwide. Lifestyle in general, and dietary habits in particular, influence the development of this condition. Results from epidemiological studies and clinical trials, suggest that adherence to a healthy dietary pattern, which consists of increased intake of fruits and vegetables, whole grains, fish, olive oil, and is also characterized by low intake of red meat and full fat dairy products, may protect against the development of the disease. [ABSTRACT FROM AUTHOR]

Due to the fact of constantly increasing incidence of arterial hypertension and the large role of nutrition in the treatment and prevention of this disease, the assessment of the awareness of the medical community and patients about the trends in the development of therapeutic and prophylactic diets is relevant. The aim of the research was to assess the physician and patient awareness on the trends in the development of therapeutic and prophylactic diets and different rations prescribed for hypertension prevention. Material and methods . On the SurveyMonkey platform, questionnaires were created for different medical specialties and patient of various departments. Access to the survey was free, the mailing list was carried out through the professional communities of physicians on the Internet. In turn, the doctors-respondents were asked to distribute the link for patients among those who were undergoing treatment or were on dispensary observation for the pathology of the cardiovascular system. Respondents were asked about their attitudes, knowledge, and compliance with existing dietary guidelines. The number of respondents was 300 doctors of various specialties and 300 patients. Results . The most recognizable dietary recommendations among patients were: low-calorie (41.1%), low-carbohydrate (39.4%), vegetarian (39.0%). However, the most popular (the commitment to them was the greatest) were: low in calories (27.6%), low in carbohydrates (25.6%), low in fat (24.4%). Among the doctors, the distribution was as follows - in addition to the classic therapeutic and prophylactic diets prescribed for certain diseases, the most recognizable diets were: Mediterranean (59.8%), low-calorie (59.0%), low-fat (57.3%); and the most commonly prescribed: Mediterranean (47.0%), low-carb (44.4%), low-fat (40.2%). The most recognizable dietary pattern among patients was the low-calorie diet (adherence to it was also maximum). As for physicians, the most recognized and most recommended preventively was the Mediterranean eating pattern. At the same time, the prevalence and recognition of the DASH diet, which, according to the opinion of the world community, has the most pronounced preventive and therapeutic properties, according to the survey, was low (7.3% of the respondents were aware of this diet). Conclusions . According to the results of this work, it is necessary to consider the possibility of combining three diets (low-calorie, Mediterranean and DASH diets) to achieve the maximum therapeutic and preventive effect while maintaining popularity among patients., Competing Interests: The authors declare no overt and potential conflict of interest related to the publication of this article., (Copyright© GEOTAR-Media Publishing Group.)

For the integral assessment of diet, tools have been proposed, called nutritional quality indices, and, as separate options, healthy eating indices (HEI), which assess diets in relation to compliance with existing national recommendations for healthy eating for the population. The aim of this work was to investigate the suitability and reliability of the developed baseline HEI for assessing the nature of the diet, modifications of the diet and eating behavior of the population. Methods . To analyze the suitability and reliability of the HEI for assessing the features of dietary intake and eating behavior of the population, the data on the actual nutrition and eating behavior of adults 19+ years of both sexes obtained by Rosstat in 2013 and 2018 have been used. Along with using the 24-hour food replay method to study actual food intake, the questionnaires included a form for assessing the frequency of consumption of major food groups in a standard format: daily or several times a week, once a week, several times a month, once a month or less often, practically do not consume. Results . The average HEI values for women in all food consumption groups are significantly higher than for men (p<0.01). Changes in average HEI values depending on the level of consumption of various products are multidirectional. When foods such as grains, vegetables and fruits are consumed in quantities greater than the median, the HEI is significantly higher than when consumed at less than the median level. On the contrary, when consuming more than the median of meat products, fatty products and confectionery products, as well as for those who consumed sausages, the HEI for both women and men is significantly lower than for those who consumed less than the median or did not consume these products. The average HEI values in men and women who consumed cottage cheese, kefir or yogurt are significantly higher than among those who did not consume these foods. Significantly higher HEI values were found in vegetarians compared to non-vegetarians. The average HEI values of adults of both sexes in autumn are significantly higher than in spring, which is confirmed by the significantly higher consumption of vegetables and fruits in autumn, w hich are components- indicators of the integral HEI. The dependence of the HEI values on the frequency of consumption of the main food groups, which are its components or affect the consumption of components, has been shown. The higher the frequency of consumpt ion of meat products, butter, salad dressings, chocolate and sweets or sweet carbonated drinks the lower is the HEI. On the other hand, the higher the frequency of consumption of vegetables, fruits, milk, fermented milk, cottage cheese or curd the higher is the HEI. Conclusion . The changes in the values of the HEI at various values, as well as the frequency, of food consumption indicate the possibility of HEI using as a marker for assessing the relationship between diet, health status and the incidence of chronic noncommunicable diseases., Competing Interests: The authors declare no overt and potential conflict of interest related to the publication of this article., (Copyright© GEOTAR-Media Publishing Group.)

The last two or three decades in the epidemiology of nutrition empirical approaches to assessing the diet of the population are increasingly being used. However, in Russian studies, these approaches are used extremely rarely, which may be due to insufficient knowledge of the essence, methodological aspects and the field of application of posterior dietary patterns. In this regard, the aim of this review was to highlight the essence, methods and main results of using empirical approaches to assessing the diet of the population. Results. This review discusses the main methodological features of multivariate analysis methods - factor analysis (principal component analysis) and cluster analysis. The main trends of dietary patterns characteristic of the epidemiology of nutrition, and various in different countries and regions are shown. The results of studies of the impact of dietary patterns on some indicators of health status (cardiovascular and oncological diseases, diseases of the musculoskeletal system, diabetes mellitus, metabolic syndrome and its components, mortality) are considered. A brief description of the few Russian studies that used the principal component method in identifying empirical dietary patterns of population is given. In general, this review indicates that the use of multidimensional statistics to highlight population dietary patterns as part of an empirical assessment is nowadays one of the most important components of nutrition epidemiology in different countries. An empirical assessment allows us to consider the diets of the population from a factual point of view and significantly supplements the scientific knowledge obtained using other epidemiological approaches. Currently, considerable experience in the development of methodological approaches to dietary patterns, as well as in the analysis of their associations with various indicators of health status has been accumulated. Conclusion. All this testifies to the high relevance of the considered epidemiological approaches and the need for their testing in Russian conditions, which, perhaps, will give new knowledge about the dietary patterns formation and its impact on the health status of Russians., Competing Interests: The authors declare no overt and potential conflict of interest related to the publication of this article., (Copyright© GEOTAR-Media Publishing Group.)

Currently, in the epidemiology of nutrition, methodological approaches to the empirical assessment of the diets of the population and their relationship to health indicators are actively using. In Russia, these approaches have been used in a number of cohort and regional studies, however, such studies are not available for the entire Russian population. Aim . Identification of empirical dietary patterns in the Russian population and analysis of their associations with risk factors for chronic non-communicable diseases. Material and methods . The work was carried out as part of a multicenter epidemiological study "Epidemiology of cardiovascular diseases in the regions of the Russian Federation" (ECVD-RF) in 2013-2014. The final sample size was 19 520 people aged 25- 64 years. Arterial hypertension, general and abdominal obesity, hypercholesterolemia, hypertriglyceridemia, low HDL, high LDL, and hyperglycemia were observed as risk factors for chronic non-infectious diseases. The data on the frequency of consumption of 13 food groups, which were grouped into 10 groups by combining dairy products into one were collected by interviewing. The identification of dietary patterns and assessment of their sustainability was performed using factor analysis (principal component analysis). In accordance with the individual commitment of the participants to the selected dietary patterns the sample was grouped into quartiles for each of the patterns. In order to ensure associations between patterns commitment and risk factors, a logistic regression analysis was used adjusted for the socio-demographic characteristics of the participants. Results and discussion . Four stable dietary patterns with a total specific gravity of the explained variance of 55.9% were identified and conventionally designated as "Reasonable" (milk, sweets and confectionery, fresh fruits and vegetables, cereals and pasta), "Salt" (sausages, pickles and pickled products), "Meat" (meat, fish and seafood, poultry meat) and "Mixed" (beans, pickles and pickled products, fish and seafood). The set of products of the "Reasonable" patterns mainly corresponds to the "Healthy" or "Balanced" patterns in foreign studies, the combination of the "Salt" and "Meat" patterns - the "Western Salt". Adherence to a "Reasonable" pattern was associated with a decrease in the likelihood of risk factors for chronic non-communicable diseases, and to a "Salt" and "Meat" patterns, on the contrary, with an increase. The associations obtained generally correspond to the results of similar foreign studies. A "Mixed" dietary pattern was associated with a few risk factors, which did not allow an unambiguous assessment of the pattern in terms of its impact on health. Conclusion . The study identified empirical dietary patterns of the Russian population and characterized them in terms of associations with the state of health of risk factors for chronic non-communicable diseases., Competing Interests: The authors declare no overt and potential conflict of interest related to the publication of this article., (Copyright© GEOTAR-Media Publishing Group.)