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Aim: To improve immediate results of treatment in patients with breast cancer using a new method of reconstruction., Material and Methods: Prospective study included 215 patients with breast cancer. Patients were treated at the Samara Regional Clinical Oncology Center in 2013-2016. Patients of the control group (n=111) underwent subcutaneous mastectomy followed by conventional endoprosthesis deployment with its complete muscular covering. Patients of the main group (n=104) underwent subcutaneous mastectomy with a new method of single-stage reconstruction., Results: Mean time of operation was 115±15 min in the control group and 90±10 min in the main group (p=0.000). Intraoperative blood loss reached 115±15 ml in the control group, 70±10 ml - in the main group (p=0.000). Duration of postoperative lymphorrhea was 14.6±3.5 days in the control group, 10±3.4 days - in the main group (p=0.000). Postoperative hospital-stay was 17.1±3.7 day in the control group and 14.2±2.4 days in the main group (p=0.001)., Conclusion: New surgical approach significantly improves early outcomes in patients with breast cancer in comparison with those who undergo conventional surgical repair.

Breast implant-associated anaplastic large-cell lymphoma will be identified as a separate nosological entity in the 2017 adapted WHO classification due to differences in its clinical presentations, pathogenesis, and prognosis with those of nodal and cutaneous anaplastic large-cell lymphomas. The paper gives a review of the literature and describes the authors' own clinical case of common breast implant-associated anaplastic large-cell lymphoma involving breast tissue, axillary lymph nodes, anterior chest muscles, and bone marrow. The treatment policy chosen by the authors could achieve complete remission.

Brief literature review about features of biological implants application for mammary gland reconstruction is presented in the article. Possible complications after such materials use, first experience of acellular dermal matrix administration for single-stage mammary gland reconstruction in 6 patients with breast cancer are also described. We offered surgical techniques, complications and methods of its treatment. We presented advantages of biological implant use which are consisted in decrease of surgical damage and duration of surgery, opportunity for enlargement of pocket for implant, decrease of pain syndrome.

The novel technique of the primary mammoplasty for patients with the breast cancer T1 - 2N0-1M0 was worked out. The submammar skin flap preservation provides the more natural breast form and make the breast modeling technically easier for the surgeon. The method can be applied solitary or in combination with breast prostheses. Of the 23 patients, operated on, 4 had postoperative complications. The long-term follow up revealed no tumor recurrence in these patients.

The experience of application of original method, concerning submuscular implants placement, elaborated by the authors, was presented. In 2006 - 2009 yrs the augmenting mammoplasty was performed in 26 women, ageing 23 - 43 yrs old. The operation was performed under general anesthesia, using inframammarial access. The texturated implants, filled by cohesive silicone gel, were applied. In 22 patients the results of operation was good and in 4 - fair. An adequate coverage of the implant by soft tissues in the lower and upper parts of breast was achieved in these observations. Vertical myotomy had secured the necessary weakening of m. pectoralis major and guaranteed from possible dislocation of the implant. Medial and lateral flaps of the muscle had securely covered the implant in medial and lateral parts of breast. The implant support was secured by application of lower myofascial flap in a fashion of a suspender for the ptosis prophilaxis and for secure coverage of the lower edge, making impossible its detection using palpation.