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Start Over Topic acute stroke Publication Year Range Last 50 years Language russian
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1. Modern treatment strategies in patients with vascular comorbidity Part 1. Correcting tissue energy deficiency

Author

S. A. Rumyantseva, R. G. Oganov, E. V. Silina, V. A. Stupin, S. B. Bolevich, S. P. Svishcheva, A. S. Orlova, A. N. Komarov, V. A. Orlov, O. V. Abroskina, E. V. Eliseev, O. A. Sokhova, and M. D. Bogatyreva

Subjects
vascular comorbidity, acute stroke, pre- and post-stroke disability, free radical processes, energy deficiency correction, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

The first paper of the series on the treatment of patients with vascular comorbidity (VC) is focused on the role and therapeutic potential of the correction of free radical processes (FRP) as pathogenetic factors of multifocal vascular pathology. Aim. To analyse the effects of VC on the incidence and outcomes of cerebral stroke (S), in order to create therapeutic algorithms of FRP correction. Material and methods. This prospective study included 634 S patients. The following factors were analysed: pre-stroke disability due to various VC variants; VC effects on the clinical course, as well as in-hospital and post-discharge outcomes; and FRP specifics in various VC variants. Results. VC was registered in 97% of S patients; in 45,3%, it resulted in pre-stroke disability. FRP parameters, reflecting the progression of tissue energy deficiency, differed significantly in patients with coronary heart disease, myocardial infarction, atrial fibrillation, and diabetes mellitus. Based on these findings, the therapeutic algorithms for effective energy deficiency correction have been created. Conclusion. The analysis of pre- and post-stroke disability and prevention of repeat events in cardiovascular patients has demonstrated the need for a more active implementation of modern multidisciplinary preventive programs.

Published
2012
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2. The key areas of medical therapy for ischemic stroke

Author

Andrei Viktorovich Fonyakin and L A Geraskina

Subjects
medicine.medical_specialty, Medical staff, Stroke patient, treatment, business.industry, Mortality rate, Cognition, Brain damage, medicine.disease, stroke, Psychiatry and Mental health, Clinical Psychology, prevention, medicine, Physical therapy, Life expectancy, Neurology (clinical), Neurology. Diseases of the nervous system, medicine.symptom, Intensive care medicine, business, RC346-429, Stroke, Acute stroke
Abstract

The paper considers the main therapeutic and preventive areas of management of patients with stroke, which are relied on evidence-based medicine data. To treat stroke patients is a multistep and multidisciplinary problem that starts with the emergence of the first neurological symptoms and extends over the entire life. Each period, including factors, such as the pattern of prehospital first medical aid; the rate of patient delivery to hospital; further actions of medical staff; measures for the prevention of recurrent cerebral ischemic events, cardiac complications, and cognitive disorders, is of importance in itself and serves a common aim. All efforts must aim eventually to reduce death rates in acute stroke, patient functional dependence, and recurrent brain damage rates, to prevent and timely treat cognitive impairments, to strictly adhere to the principles of secondary treatment of cardiovascular events in order to increase life expectancy and quality.

Published
2013