1. MODIFICĂRI HEPATICE ÎN SARCINA NORMALĂ.
- Author
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Buşegeanu, C., Negreanu, L., and Braticevici, Carmen Fierbinţeanu
- Abstract
Pregnancy is inducing morphologic and functional changes in pregnant woman's organism, in order to adapt it to the new condition. Among these are the hepatic changes, which has to be acknowledged by the physician, in order to differentiate the normal to the pathologic ones. The blood values of the ALAT and ASAT enzymes are, in general, increased and not considered to be abnormal, their activity being, in general, constant. Alkaline phosphatase value might be increased, due to the presence in the blood stream of the bone isoenzyme produced by placenta. Gamma glutamil transpeptidase (GGT) activity is inhibited by the maternal hormones and 5-nucleotidase might be slightly elevated, this increase being considered with low clinical significance. Bilirubin might be decreased in serum, due to hemodilution and biliary acids might be very slightly increased due to cholestasis. Among the proteins, the albumin value is decreased due to hemodilution in the second trimester and the coagulation factors are increased, in order to control potential bleeding events. Hepatic cholesterol and tryglicerides deposits are increasing in the last part of the pregnancy, to prevent any potential deficits. The hepatic semiology, laboratory tests and imagine tests (ultrasound and fibroscan) are important, as they might provide important information about hepatic functions during pregnancy, consequently monitoring them is an extremely useful process for early determination of any pathologic event during pregnancy. [ABSTRACT FROM AUTHOR]
- Published
- 2014