Search

Nutrition plays an important role in oncology, as cancer and its treatment can significantly affect the nutritional status of patients. During cancer therapy, patients may experience weight loss, decreased appetite, nausea and vomiting, diarrhea, or constipation, which may affect their overall health and ability to tolerate the treatment. Therefore, ensuring adequate nutrition can be important to maintain the nutritional status and the general health of patients during oncology therapy. Diet should be tailored to the individual needs of patients, taking into account health status, treatment and food tolerance. In addition, foods can have a direct impact on the growth and development of cancer cells, therefore some nutrients can have a protective effect against cancer. For example, foods rich in antioxidants, such as fruits and vegetables, can help prevent cell damage and reduce the risk of cancer. On the other hand, some foods and eating habits can increase the risk of cancer. For example, a high consumption of processed foods, foods high in saturated fat and sugar can increase the risk of cancer. Alcohol consumption and smoking are also known risk factors for cancer. New research combines precision oncology and precision nutrition by integrating information on tumor nutrition and metabolism, patient genomics and cancer cell metabolism, and even the patient’s microbiome that may lead to new approaches to cancer prevention. Good results have been achieved when molecularly targeted therapies and immunotherapy have been used to treat specific forms of cancer together with molecular oncology and molecular nutrition [ABSTRACT FROM AUTHOR]

Hemangiomas are the most common tumor of infancy and are caracterized by a initial rapid growth followed by a slow involution. We raport a novel human in vitro model for hemangioma tissues. Our aim is to abtain small fragments of hemangioma tissue and to use it in our culture sistem. The hemangioma fragments were followed for 20 days and any changes and cells groth was noted. Corelations between clinical aspect and in vitro behaviour of hemangiomas were made. Fragments obtained from all three phases of hemangioma clinical stage were cultured successfully. Proliferative samples showed a rapid growth of new cells, and involuting phase samples developed a slow and late growth, or no growth was noticed. This in vitro culture sistem offers an oportunity for studying the biochemical and molecular basis of hemangiomas, a good way to study the angiogenesis, and also help to elucidate the mecanisms of action of existing therapies and to identify novel treatments for hemangiomas. [ABSTRACT FROM AUTHOR]

Understanding the biological progression of metastatic disease ,with origin at the level of head and neck towards the cervico-facial node stations, allowed the development of changes in classic radical neck dissection, in order to reduce morbidity and maintain therapeutic effectiveness [ABSTRACT FROM AUTHOR]