1. [Studying erythrocyte deformation by optical methods]
- Author
-
Diana, Lăcătuşu and V, Rusu
- Subjects
Adult ,Diamide ,Male ,Optics and Photonics ,Radiation-Sensitizing Agents ,Hot Temperature ,Erythrocyte Deformability ,Lasers ,Humans ,Female ,Middle Aged ,Algorithms ,Software - Abstract
Erythrocyte deformation is an important factor of the microcirculation in physiological and pathophysiological conditions.Deformability was evaluated through the elongation index (IE) using two instruments based on optical methods: LORCA and RHEODYN-SSD.The elongation index (IE) was compared for normal red blood cell (RBC) and heated RBC at 49 degrees C for 9, 30, 60 minutes duration. Erythrocyte deformability was measured for RBC treated with diamide (two concentrations), too. The results show that the increase of the diamide concentration induces the increase of the rigidity and a decreased deformability through the decreased IE. The elongation index was found decreasing as long as the time of heating is bigger, the RBC becoming more rigid.
- Published
- 2011