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There is ample literature evidence to support that periodontal therapy has an impact on the local and systemic host immune responses, despite contradicting data from the literature reporting both a decrease and increase in systemic antibody levels following treatment. The clinical guidelines for the treatment of patients with periodontitis stages I–III published from the European Federation of after the patient has been informed about his/her condition, the first step in the treatment process is directed toward motivation, targeting behavioral changes to achieve adequate self-performed oral hygiene practices and controlling local and systemic modifiable risk factors. A systematic review indicates positive associations across patient-reported experiences, self-rated and objectively measured health outcomes in relation to a wide range of areas and settings. Despite patient-reported experiences and patient-reported outcomes of therapy being closely related, there are differences between the two concepts. Frequent re-evaluation of oral hygiene reinforcement outcomes is suggested, aiming to reinforce a patient’s motivation and keep the patient up to date with any changes that might occur in the periodontal status, enabling the patient to actively participate in the progress of the treatment plan. In conclusion, short-term perturbations of antibody responses occur during the active phase of periodontal therapy.

This narrative review summarizes the current evidence about the role that the fabrication and presence of dental prostheses and tooth-related factors have on the initiation and progression of gingivitis and periodontitis. Tooth anatomic factors, such as root abnormalities and fractures, and tooth relationships in the dental arch and with the opposing dentition can enhance plaque retention. Tooth-supported and/or tooth-retained restorations and their design, fabrication, delivery, and materials have often been associated with plaque retention and loss of attachment. Hypersensitivity reactions can occur to dental materials. Placement of restoration margins within the junctional epithelium and supracrestal connective tissue attachment can be associated with gingival inflammation and, potentially, recession. Restoration margins located within the gingival sulcus do not cause gingivitis if patients are compliant with self-performed plaque control and periodic maintenance. The presence of fixed prostheses finish lines within the gingival sulcus or the wearing of partial, removable dental prostheses does not cause gingivitis if patients are compliant with self-performed plaque control and periodic maintenance.

Periodontitis patients are known to have increased circulating lipopolysaccharide activity and metabolic disturbances, which may be either the cause or effect of endotoxemia. This review approaches endotoxemia as a possible molecular mediator between periodontitis and increased risk of cardiometabolic disorders. Observations that bacteria disseminate into circulation after toothbrushing and periodontal procedures and assumptions that endotoxin may disseminate through inflamed periodontium and bleeding gums support the idea of endotoxemia in periodontitis. However, the evidence that periodontitis-associated dysbiosis contributes to endotoxemia is not as strong as in the case of gut microbiome dysbiosis. We describe the structure-function relationship of lipopolysaccharide, the local and systemic inflammatory and immunological responses caused by lipopolysaccharide, current knowledge on endotoxemia in periodontitis, factors affecting the levels of endotoxemia, and its relation to cardiometabolic disorders. They are physically, microbiologically, and biochemically connected to each other, and only crumbs of information are known about this connection. Although the causality is insufficiently demonstrated thus far, many studies have associated changes of the gut microbiome composition, function, and specific bacterial metabolites with cardiometabolic diseases, whereas research on the oral microbiome has severely fallen behind.

Introduction. As the area of nano-based platforms for antimicrobial treatment aimed at pathogenic oral biofilms continues to expand, this review serves to bring together researchers from several disciplines to foster more collaboration and discovery among dental practitioners.

The aim of this review is to provide an overview of the current evidence of some popular food supplements and superfoods that might be of interest in periodontology. Although the number of publications investigating the effect of these products on human health and their possible use in medicine is increasing, only little is known so far regarding their effects on periodontal tissues and their possible use in periodontal treatment or medicine. In summary, an increasing number of studies have revealed aspects and effects of these so-called lifestyle or fitness supplements and superfoods that may have an impact on periodontal health and healing after treatment. However, some the current evidence is of a very low quality, and more validated scientific data are required before their possible use in prevention or treatment of periodontal diseases can be made.

Periodontology has been defined as the scientific study of the periodontium in health and disease. The objective of this overview of principles of periodontology is presentation of current and established concepts. Aspects of the history, classification and epidemiology of the most common periodontal diseases are discussed. People exhibiting periodontal abnormalities, for example impairments of tissue integrity or function, are said to have periodontal diseases. Periodontal diseases are arguably among the most ancient and common infectious diseases affecting humans, leading to permanent destruction of the supporting structures of the dentition and ultimately tooth loss. The new classification is complex and will take time to fully incorporate into patient care globally.

Periodontal diseases are arguably among the most ancient and common infectious diseases affecting humans, leading to permanent destruction of the supporting structures of the dentition and ultimately tooth loss. It has been established that dental biofilm (‘‘plaque’’), consisting of many microbial species and their products, is an etiological agent of periodontal disease. It is widely accepted that immunological and inflammatory responses to dental plaque via hostparasite interaction are manifested by clinical signs 40 Dentino et al. and symptoms of periodontal diseases.

The interrelation between orthodontics and periodontics is evident. In daily practice is common to meet patients with periodontal disease associated with dental malpositions. In addition, it is also common to observe dental migrations secondary to periodontal disease. In this context, the dentist may have to question the possibility and the necessity of orthodontic treatment. The question is if orthodontic treatment improves the existing periodontal situation and if is possible to perform orthodontic treatment on a reduced periodontium without causing other complications. This review highlights three most important periodontal complications of the orthodontic treatment and it assesses the necessity of the periodical periodontal controls and treatments before, during and after the orthodontic treatment.

Aim of the study Over time, the aesthetic solutions for different types of restorations have become more complex requiring knowledge of the biodynamic and aesthetic principles of the materials and the characteristics of these materials in order to obtain a ceramic fixed prosthesis that is considered optimal from all points of view. Material and methods The case report is represented by a 30-years old patient, who need an aesthetic rehabilitation of anterior dental arch by applying a ceramic fixed prosthesis with zirconia framework. Results The Zirconium Framework construction stage was done with the aid of the CAD-CAM system. The CAD component virtually realizes the design of the future zirconium framework, and the CAM component physically realizes this framework structure based on the data previously provided. In order to achieve the aesthetic component of the structure so prepared, we are passing the application stages of the ceramic masses – VITA VM 13 ceramic masses. Conclusions Particular properties of ceramic masses and zirconium, especially, – a varied Chroma, close to a vital tooth, brightness and translucency, will allow the development of aesthetic restorations and their guiding towards natural integration.

The medical and dental fields are experiencing a significant shift in approach thanks to the integration of artificial intelligence (AI). With a vast influx of patient data, there is a pressing need for sophisticated software capable of organizing and preserving this information effectively. The emergence of AI-driven models and computer vision techniques for identifying patterns in clinical and histopathological images related to oral pathology lesions holds promise for enhancing diagnostic accuracy and prognostic predictions. While microscopic morphology remains the gold standard in diagnostic pathology, its reliance on individual pathologists introduces variability. Consequently, AI presents a potential solution for achieving consistent and more precise diagnoses. Moreover, by analyzing extensive data from the patients’ medical chart the artificial neural network could provide a presumptive diagnosis and an invaluable screening tool in predicting individual risk for oral pathology based on information regarding their risk factors, systemic diseases and conditions and clinical pathological data. Within oral and maxillofacial pathology, AI stands poised to elevate diagnostic accuracy, tailor treatment, and ultimately enhance patient outcomes. Nevertheless, the integration of AI in healthcare demands meticulous attention to ethical, legal, and regulatory complexities. Moreover, given the nascent nature of AI technology, prudence is paramount when deploying it in this specialized domain.

This study aimed to evaluate the degree of periodontal involvement in subjects with and without bruxism, with generalized chronic periodontitis of varying severity grades, and to assess the effects of occlusal correction therapy in association with non-surgical periodontal therapy on periodontal status. The following periodontal parameters were analyzed: probing depth (PD), clinical attachment level (CAL), Papilar bleeding index (PBI) and Plaque Index (PI), and X-rays, at the initial (pre-therapeutic) moment and at 3 months after therapy completion. The present study demonstrated that bruxism generates significant clinical changes in a periodontopathic environment. High values of periodontal attachment loss, recessions, missing teeth, tooth mobility, and furcation lesions translate into major losses of periodontal tissue in patients with periodontal disease and bruxism. Periodontal therapy, combined with occlusal correction and bruxism therapy, resulted in statistically significant improvements in periodontal parameters. Thus, occlusal trauma therapy in patients with bruxism becomes an absolute necessity in periodontal therapy.

It is important for patients to understand that these conditions can be treated, but the success of treatment greatly depends on their level of oral hygiene. Selecting the appropriate toothbrush and mastering the correct brushing technique to effectively remove dental plaque while avoiding any potential damage to the gums. In addition to toothbrushes, there are other devices available for comprehensive dental cleaning, such as floss, interdental sticks, interdental brushes, and oral irrigators. Currently, self-care recommendations for dental implants are primarily based on existing knowledge regarding natural teeth cleaning. Patient education on oral hygiene is an important component of their overall treatment. Maintaining a regular oral hygiene routine is essential for taking care of our mouths, ensuring healthy teeth, and achieving fresh breath. In conclusion, biofilm disruption mechanical methods integrated is indispensable for comprehensive oral healthcare.