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This article is based on the quantitative part of a research in ergonomics whose goal is to understand how work modifications boosted or limited the occurrence and persistence of musculoskeletal disorders (MSD) among operators of an aeronautical industrial group, with a diachronic approach of the empirical evidence. An observatory, based on the systematic collection of quantitative data from operators (Evrest device) allows connecting operators' past and present MSD risk factors with their musculoskeletal health. On this basis, regulation, wear and selection mechanisms possibly in action are explored. For the last two mechanisms, the analysis is based on the study of "constraint sequences" and "constraint accumulation". The constraint is defined from a combination of questions about the physical constraints, the time pressure and the opportunities to choose how to proceed in work. [ABSTRACT FROM AUTHOR]