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2 results on '"Drug response"'

1. Psicofarmacogenética: uma nova abordagem terapêutica

Author

Homero Pinto Vallada Filho

Subjects
medicine.medical_specialty, Psychopharmacogenetics, Psicofarmacogenética, genes de suscetibilidade, business.industry, lcsh:RC435-571, medicine.medical_treatment, resposta terapêutica, Susceptibility gene, Psychiatry and Mental health, lcsh:Psychiatry, medicine, Drug response, susceptibility genes, Psychopharmacology, Antipsychotic, business, Psychiatry, drug responders
Abstract

A psicofarmacogenética é uma nova área de investigação derivada da psicofarmacologia e da genética. Esta disciplina procura identificar genes de suscetibilidade associados a diferentes padrões de resposta terapêutica e/ou ao variado grau de efeitos colaterais dos psicofármacos. O presente artigo discorrerá, após um breve histórico, sobre alguns exemplos de variantes genéticas relacionadas com a resposta terapêutica de antipsicóticos e antidepressivos.Psychopharmacogenetics is a new area of investigation originating from the application of genetics to psychopharmacology. This discipline attempts to identify susceptibility genes which are responsible either for the drug response of a treatment or for the side effects of different psychopharmarcological drugs. The present article will discuss, after a brief historical background, some examples of gene variants which are associated with the therapeutic response of antipsychotic and antidepressive drugs.

Published
1999

2. Alterações eletrocardiográficas observadas durante o uso do trimetafano no tratamento da hipertensão arterial maligna

Author

Soares, V. A., Trezza, E., and Universidade Estadual Paulista (Unesp)

Subjects
Adult, Male, therapy, hypertension, iatrogenic disease, heart ventricle fibrillation, human cell, electrocardiography, adverse drug reaction, drug response, English Abstract, Hypokalemia, heart, hypocalcemia, drug therapy, Hypertension, Malignant, female, dose response, Ventricular Fibrillation, cardiovascular system, human, malignant hypertension, trimetaphan, Trimethaphan
Abstract

Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-26T15:42:36Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:38:08Z : No. of bitstreams: 1 2-s2.0-0018142643.pdf: 82441 bytes, checksum: 408e0e25779757b7938441723fb3946c (MD5) Made available in DSpace on 2014-05-26T15:42:36Z (GMT). No. of bitstreams: 0 Previous issue date: 1978-12-01

Published
1978

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