19 results on '"B. Miranda"'
Search Results
2. NEURO-FUZZY MODELING OF EYEBALL AND CREST TEMPERATURES IN EGG-LAYING HENS
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Ana C. de S. S. Lins, Dian Lourençoni, Tadayuki Yanagi Júnior, Isadora B. Miranda, and Italo E. dos A. Santos
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Neuro-fuzzy ,Thermography ,Poultry farming ,Simulation ,Artificial intelligence ,Agriculture (General) ,S1-972 - Abstract
ABSTRACT Considering the challenges faced by poultry farming, this study aimed to develop a neuro-fuzzy model to predict eyeball and crest temperatures of egg-laying hens based on environmental conditions (dry bulb temperature and relative humidity). To develop the models and simulations, Matlab’s Fuzzy Toolbox® (Anfisedit) was used. Different configurations were used for each of the several neuro-fuzzy models developed. Eyeball temperature (ET) and chicken crest temperature (CCT) were simulated from the developed neuro-fuzzy models, and the obtained results were validated with the variables collected experimentally with the aid of recorder sensors and an infrared thermographic camera. The proposed neuro-fuzzy models allow the accurate estimation of ET and CCT of two lineages of egg-laying hens raised in conventional aviaries, thus helping in decision-making for better animal welfare.
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- 2021
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3. FUZZY MODELING FOR RAPID COOLING OF TABLE GRAPES IN DIFFERENT PLASTIC FILM BAGS
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Magno do N. Amorim, Isadora B. Miranda, Ítalo E. dos A. Santos, Dian Lourençoni, and Silvia H. N. Turco
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Vitis vinifera L. ,artificial intelligence ,palletization level ,relative humidity ,weight loss ,Agriculture (General) ,S1-972 - Abstract
ABSTRACT Rapid cooling is necessary to remove heat from fruit; however, it directly affects the water loss of grapes under certain conditions. Fuzzy logic is an important theory for analyzing results as it simplifies the assimilation of the phenomena through refined adjustments, allowing the prediction of the weight loss of fruits in relation to rapid cooling conditions. The objective of this study was to develop a fuzzy model that could predict weight loss as a function of the rapid cooling of table grapes in different plastic film bags. Modeling was performed using three types of plastic film bags (micro-perforated, macro-perforated, and non-perforated) at three levels of palletization (lower, intermediate, and upper), arranged in an experimental design in randomized blocks, in a 3 × 3 factorial scheme, with three blocks. The influence of the relative humidity and amplitude of humidity on the variable weight loss percentage of the Arra 15 grape variety was measured. The average percentage error of the fuzzy model was 9.78%. The intermediate level alone showed an error of 4.02%. Thus, the developed fuzzy model provided a good prediction of the weight loss of table grapes.
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- 2022
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4. Análisis Exploratorio de la Implicación Académica en Entrevistas a Ingresantes a Psicología
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Adriana B. Miranda, Carolina Nonis, María Virginia González, Mónica Alejandra Soave, Luciana Juaneu, and Ignacio Acuña
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Implicación Académica ,Dimensión Conductual ,Dimensión Afectiva ,Dimensión Cognitiva ,Psychology ,BF1-990 - Abstract
En este estudio tuvimos como objetivo explorar la Implicación Académica, identificar elementos que conforman las Dimensiones Conductual, Afectiva, Cognitiva y determinar dimensión prevalente en entrevistas tomadas a alumnos de primer año de la Facultad de Psicología de la Universidad Nacional de Córdoba. Trabajamos con datos secundarios provistos por la Cátedra Entrevista Psicológica. La muestra estuvo compuesta por 50 entrevistas seleccionadas al azar de un total de 500. Se evaluó en cada entrevista presencia/ausencia de indicadores que dieran cuenta de cada Dimensión. Estos datos se incorporaron en una grilla construida Ad-Hoc. Determinamos Dimensión prevalente por cálculo de Moda. Se obtuvieron porcentaje altos de respuestas positivas en subcategoría “Técnicas de Estudio” y “Expectativa en la Asignatura”, lo que define la Dimensión Cognitiva como prevalente. Consideramos necesario implementar estrategias que fortalezcan la Dimensión Cognitiva, promover el desarrollo de las otras Dimensiones, fomentando la participación, generando interés y mayor comprensión del material.
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- 2017
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5. PREVALENCE OF HPV IN ASYMPTOMATIC PATIENTS IN THE EXTREME WEST OF SANTA CATARINA
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L. Frantz, G. R. Weber, C. Dannebrock, and G. B. Miranda
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Molecular Diagnostic Techniques ,Cervix Uteri ,PCR ,General Works - Abstract
The human papillomavirus (HPV) is the most common sexually transmitted virus in the world and is considered a risk factor for developing cervical cancer. The objective of this study was to observe the sensibility to detect the presence of HPV by PCR in samples of cervical material, compared to cytologic results and determine the viral prevalence in asymptomatic patients in the extreme west of Santa Catarina. For this study were sampled 496 women living in the extreme west region of Santa Catarina. The samples underwent cytologic test and the PCR technique. The results showed which 12.7% of samples were positive for the presence of viral DNA by PCR test, while that the cytologic tests detected cellular changes in 2.4% of the samples. The results demonstrate that the use of molecular techniques for proving the presence of HPV is significantly more sensitive than cytological tests (P < 0.0001). The prevalence found in this study was within the pattern found in other studies, which ranged from 10.6% to 17%.
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- 2014
6. Filmes ultrafinos de ésteres de celulose: preparo, caracterização e imobilização de proteínas Ultrathin cellulose ester films: preparation, characterization and protein immobilization
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Jorge Amim Jr., Denise F. S. Petri, Francisco C. B. Maia, and Paulo B. Miranda
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cellulose ester ,protein adsorption ,film characterization ,Chemistry ,QD1-999 - Abstract
In this study cellulose acetate butyrate (CAB) and carboxymehtylcellulose acetate butyrate (CMCAB) films adsorbed onto silicon wafers were characterized by means of ellipsometry, atomic force microscopy (AFM), sum frequency generation spectroscopy (SFG) and contact angle measurements. The adsorption behavior of lysozyme (LIS) or bovine serum albumin (BSA) onto CAB and CMCAB films was investigated. The amounts of adsorbed LIS or BSA onto CMCAB films were more pronounced than those onto CAB films due to the presence of carboxymethyl group in the CMCAB structure. Besides, the adsorption of BSA molecules on CMCAB films was more favored than that of LIS molecules. Antimicrobial effect of LIS bound to CAB or CMCAB layers was evaluated using Micrococcus luteus as substrate.
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- 2010
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7. A IMPORTÂNCIA E AS VANTAGENS DO POLIHIDROXIBUTIRATO (PLÁSTICO BIODEGRADÁVEL)
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B C Coutinho, G B Miranda, G R Sampaio, L B S de Souza, W J Santana, and H D M Coutinho
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General Works - Abstract
Do início do século passado aos dias atuais o uso dos polímeros tem se tornado cada vez mais freqüente na sociedade. Existe uma incrível quantidade de artigos que utilizam polímeros como matéria-prima para suas diferentes elaborações. A busca inicial por polímeros sintéticos esteve baseada em sua relativa inércia e resistência a biodegradação. Devido a essas características, a enorme quantidade de lixo produzido nas cidades tornouse um sério problema, estimulando a substituição desse material de difícil degradação por um polímero natural biodegradável, o Polihidroxibutirato (PHB), alvo das pesquisas atuais. A importância do PHB está no fato de poder ser usado na fabricação de diversos produtos. O tempo médio de degradação desses bioplásticos é de 6 a 12 meses contra 40 a 50 anos ou até 200 anos no caso dos polímeros sintéticos. Apesar da vantagem no critério ambiental, os plásticos biológicos são mais caros e, por serem menos flexíveis, têm aplicações mais limitadas que os sintéticos. Palavras-chave: Polihidroxibutirato; PHB; Biodegradação; Indústria
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- 2007
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8. Nuclear and isotopic techniques application used in supporting nutritional studies in Latin America countries
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N Mokhtar, J Gerardo-Abaya, B Miranda da-Cruz, Seong Ai Kim, and G.V Iyengar
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Nutrición ,isótopos estables ,América Latina ,Nutrition ,stable isotopes ,Latin America ,Nutrition. Foods and food supply ,TX341-641 ,Biology (General) ,QH301-705.5 - Abstract
SUMMARY. The global nutrition community recognizes the usefulness of nuclear and isotopic techniques and especially stable isotopes for accurate measurements in key areas of human nutrition and health. Although progress has been made in many Latin America countries in reducing the absolute number of undernourished people, food policy and public health communities have to face the double burden on health. On one side they have to address the prevention of obesity and on the other side they are trying to reduce under-nutrition. However, to be successful in development of sustainable nutrition programs, a combination of relevant scientific knowledge and approaches that are practical is required to assure even a reasonable level of success. The objectives of this review are to highlight the role of isotopic techniques in nutritional studies and to review the role of the International Atomic Energy Agency in supporting nutrition interventions in Latin America countries.Resumen. La comunidad global de la nutrición reconoce la utilidad de técnicas nucleares e isotópicas y especialmente de isótopos estables para las medidas exactas en las áreas dominantes de la nutrición humana y de la salud. Aunque se ha progresado en muchos países de América Latina en la reducción el número absoluto de desnutridos en la populación y política alimenticia. Las comunidades de la salud pública tienen que hacer frente a la carga doble en la salud. Por un lado se tiene que tratar la prevención de la obesidad y, por otro lado, se está intentando reducir la malnutrición y la pobreza. Para ésto, el conocimiento científico relevante y el arte de la práctica son necesarios para ser acertados en el desarrollo de los programas sostenibles de la nutrición. Los objetivos de esta revisión son destacar el papel de técnicas isotópicas en estudios nutricionales y revisar el papel del Organismo Internacional de Energía Atómica (OIEA) en la intervención y soporte del estado de la nutrición en los países de América Latina.
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- 2004
9. Soroprevalência de HBsAg positivo em mulheres atendidas em clínica de Doenças Sexualmente Transmissíveis
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Angélica E. B. Miranda, Estephânia G. Nogueira, Evanira S. Ribeiro, Kelly R. Area, and Marta C. Alves
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Hepatite B ,mulheres ,clínica DST ,Medicine - Abstract
Objetivos: Estimar a soroprevalência de HBsAg positivo entre mulheres atendidas em uma clínica d e DST e m Vitória. Método s: Estudo de corte-transversal foi condu-zido d e Janeiro a Dezembro de 1997. Todas as mu-lheres foram convidadas a participar do estudo, elas responderam a uma entrevista contendo dados só-cio-demográficos e comportamentos de risco. Uma amostra d e sangue foi coletada para hepatite B . De-tecção d e HbsAg foi obtida em dois passos (triagem e teste confirmatório) usando um teste ELISA. Resultados: Quatrocentos e dez mulheres foram testadas para hepatite B, a taxa de prevalência foi d e 5 ,4 %. A média de idade foi de 28,3 (SD9,3). Em relação à educação, 7, 1 % eram analfabetas, 69 ,2% tinham somente o curso primário, 20,2% o curso secundário e 3,5% estavam na universidade. Con-siderando o estado marital, 46,5% das mulheres eram c a sadas e 53,5% eram não casadas. Sessenta e nove mulheres relataram um parceiro fixo nos últimos cinco anos. História de DST foi relatada por 18,2 % mulheres e 67% relatou nunc a ter usado preservativos. Somente 1,4 % delas relatou uso de drogas injetáveis e 2 ,5% tinha história de transfu-são de sangue. Fatores de risco dos parceiros sexu-ais incluíram: UDI 12% , bissexual 2 ,7 % , múltiplos parceiros 18%. Não houve associação estatistica-mente significativa entre as variáveis testadas. Foi observado uma tendência de associação em rela-ção à infecção pelo HIV [2.2 (0.59-7.89)] e sífilis [2.6 (0 .70-9.65)]. Conclusão: A alta prevalência de HBsAg positi-vo encontrada neste estudo mostra a necessidade da implementação de programas de vacinação e aconselhamento para est a população porque são mulheres jovens com vida sexual e risco de trans-missão vertical.
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- 1999
10. Seropositive pigs to Toxoplasma gondii (Apicomplexa: Toxoplasmatinae) sent to slaughter and destined for human consumption
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Wanderley M. de Almeida, Zander B. Miranda, Walter Flausino, Cleide D. Coelho, Ana Beatriz M. Fonseca, and Carlos Wilson G. Lopes
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suínos ,Inspection Service ,Veterinary medicine ,SF600-1100 ,Toxoplasma gondii ,pigs ,RIFI ,Serviço de Inspeção - Abstract
de Almdeida W., Miranda Z.B., Flausino W., Coelho C.D., Fonseca A.B.M. & Lopes C.W.G. [Seropositive pigs to Toxoplasma gondii (Apicomplexa: Toxoplasmatinae) sent to slaughter and destined for human consumption.] Suínos sororreagentes a Toxoplasma gondii (Apicomplexa: Toxoplasmatinae) enviados para abate e destinados ao consumo humano. Revista Brasileira de Medicina Veterinária, 37(4):397-400, 2015. Curso de Pós-Graduação em Medicina Veterinária - Higiene Veterinária e Processamento Tecnológico de Produtos de Origem Animal, Faculdade de Veterinária, Universidade Federal Fluminense, Rua Vital Brasil Filho, 64, Vital Brazil, Niterói, RJ 24230-340, Brasil. E-mail: wanderleyma@yahoo.com.br This study aimed to determine the frequency of pigs seropositive to Toxoplasma gondii by indirect immunofluorescence assay with cutoff 1:16. Of blood samples collected at slaughter, 250 of them were from animals raised in the State of Minas Gerais; while 181 were from the State of Rio de Janeiro with a total of 431 examined samples. Of these, 19/250 (4.41%) of MG and 39/181 (9.04%) of RJ, determining a total of 13.45% seropositive animals. Regardless of slaughter be under the control of the inspection service, the precedence of the animals was highly significant (p = 0.0001) in the number of seropositive animals. Although the percentage of seropositive animals to T. gondii from both regions studied in this work, and from the point of view of a public health problem, pork and its frescal type products may continue to be considered as a source of infection of this coccidia for humans, if they are consumed as raw or undercooked., Este estudo teve como objetivo determinar a frequência de suínos serorreagentes a Toxoplasma gondii pela reação de imunofluorescência indireta com ponto corte de 1:16. Das amostras de sangue coletadas no momento do abate, 250 delas eram de animais criados no estado de Minas Gerais; enquanto que 181 eram do estado do Rio de Janeiro, com um total de 431 amostras examinadas.Destas, 19/250 (4,41%) de MG e 39/181 (9,04%) do RJ, determinando um total de 13,45% de animais sororreagentes a T. gondii. Independentemente do abate ser sob o controle do serviço de inspe- ção, a precedência dos animais foi determinante (p=0,0001) quanto ao número de animais sororreagentes. Apesar do percentual de animais soropositivos a T. gondii de ambas as regiões estudadas neste trabalho, do ponto de vista de um problema de saúde pública, a carne de porco e seus produtos tipo frescal podem continuar a ser considerados como fonte de infecção deste coccidia para seres humanos, caso sejam consumidos, crus ou mal-cozidos.
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- 2015
11. Determinação da fixação biológica de nitrogênio no amendoim forrageiro (Arachis spp.) por intermédio da abundância natural de 15N
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Georg Cadisch, Cesar H. B. Miranda, and Antônio Assis Vieira
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forage legumes ,cerrados ,isótopos de 15N ,Brazilian savanna ,Animal Science and Zoology ,Bradyrhizobium ,leguminosas ,15N isotopes ,leguminosas forrageiras - Abstract
Quantificou-se a fixação biológica de nitrogênio (FBN) em cinco acessos de Arachis pintoi (BRA31534, BRA31828, BRA31796, BRA15121 e BRA30333) e dois de A. repens (BRA31801 e BRA31861). Os mesmos foram estabelecidos em um solo Latosolo Vermelho Escuro sujeito a inundação estacional, sendo a FBN estimada segundo a técnica da abundância natural do isótopo 15N (d15N). Estolões dos acessos foram plantados em novembro de 1999, em parcelas de 2,0 m x 2,0 m, com quatro repetições, distribuídas em blocos ao acaso. A massa verde das plantas acima de cinco centímetros do solo foi colhida em janeiro de 2000 e seca em estufa a 65ºC até peso constante, sendo posteriormente pesada e moída para análise dos conteúdos em N e d15N, em espectrômetro de massa. Verificaram-se diferenças significativas entre os genótipos quanto à produção de matéria seca (MS) e N total, sobressaindo-se BRA31534 e BRA31828, com produções de 4,2 t/ha e conteúdos totais de N de 102 e 110 kg/ha, respectivamente. Os acessos BRA30333 e BRA31861 produziram apenas 2,6 t de MS/ha, com 59 e 65 kg/ha de N total, respectivamente. As taxas de FBN dos acessos testados, medidas por comparação dos seus teores de d15N com os de plantas não fixadoras crescendo na mesma área, variaram de 36% (BRA15121) a 90% (BRA31828) do N total das plantas, equivalente a 26 e 99 kg de N/ha, respectivamente. Verificou-se correlação positiva e significativa (r = 0,92, p
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- 2003
12. Preliminary List of the Compositae in Northeastern Brazil
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D. J. Nicholas Hind, Elaine B. Miranda, D. J. Nicholas Hind, and Elaine B. Miranda
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- Compositae--Catalogs and collections--Brazil, Northeast, Compositae--Type specimens--Brazil, Northeast, Plants--Brazil, Northeast
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A checklist of 486 species, in 143 genera, with entries listed alphabetically and sorted by state, collector and number. The list brings together the results of an examination of some 4,200 Northeastern Brazilian Compositae specimens; and is the fourth title to be published in the current series. The introductory text is presented in both English and Portuguese languages.
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- 2008
13. Women's knowledge of methods for secondary prevention of breast cancer.
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Gonçalves CV, Camargo VP, Cagol JM, Miranda B, and Mendoza-Sassi RA
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- Adult, Aged, Brazil, Breast Neoplasms diagnosis, Early Detection of Cancer methods, Educational Status, Female, Humans, Income, Middle Aged, Poisson Distribution, Secondary Prevention methods, Socioeconomic Factors, Surveys and Questionnaires, Breast Neoplasms prevention & control, Health Knowledge, Attitudes, Practice, Mammography methods, Mass Screening methods
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The objective of this study was to evaluate women's knowledge of methods for screening breast cancer. The study was done on a population of women aged 18 or over in the city of Rio Grande between April and November 2011. Interviewers used questionnaires on all of the women at selected households. Models were developed for every type of screening (self-examination of breasts, mammography, and clinical exams) that were analyzed through the use of Poisson regression. Out of the 1596 women interviewed, 1355 reported self-examination, 456, mammography, and only 191, clinical examination of the breast, performed by a health professional, as important for the prevention of breast cancer. White women with 11 years or more worth of schooling had a greater probability of having mammography exams and clinical examinations as methods for screening. We noted, linked to the aforementioned, that there was a linear tendency whereby there was a greater probability for those with high incomes to undergo one of the above interventions. The study noted that there was a need for more detailed information aimed at the population on prevention methods in order to avoid late diagnosis. We noted that non-white women with little education and on low incomes showed less knowledge of clinical examination methods and mammographies.
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- 2017
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14. Microcephaly in Pernambuco State, Brazil: epidemiological characteristics and evaluation of the diagnostic accuracy of cutoff points for reporting suspected cases.
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Souza WV, Araújo TV, Albuquerque Mde F, Braga MC, Ximenes RA, Miranda-Filho Dde B, Bezerra LC, Dimech GS, Carvalho PI, Assunção RS, Santos RH, Oliveira WK, Rodrigues LC, and Martelli CM
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- Brazil epidemiology, Female, Gestational Age, Humans, Infant, Newborn, Male, Microcephaly diagnosis, Pregnancy, ROC Curve, Sensitivity and Specificity, Zika Virus isolation & purification, Zika Virus Infection diagnosis, Microcephaly epidemiology, Pregnancy Complications, Infectious epidemiology, Zika Virus Infection epidemiology
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The increase in the number of reported cases of microcephaly in Pernambuco State, and Northeast Brazil, characterized an epidemic that led the Brazilian Ministry of Health to declare a national public health emergency. The Brazilian Ministry of Health initially defined suspected cases as newborns with gestational age (GA) ≥ 37 weeks and head circumference (HC) ≤ 33cm, but in December 2015 this cutoff was lowered to 32cm. The current study aimed to estimate the accuracy, sensitivity, and specificity of different cutoff points for HC, using ROC curves, with the Fenton and Intergrowth (2014) curves as the gold standard. The study described cases reported in Pernambuco from August 8 to November 28, 2015, according to sex and GA categories. The Fenton and Intergrowth methods provide HC growth curves according to GA and sex, and microcephaly is defined as a newborn with HC below the 3rd percentile in these distributions. Of the 684 reported cases, 599 were term or post-term neonates. For these, the analyses with ROC curves show that according to the Fenton criterion the cutoff point with the largest area under the ROC curve, with sensitivity greater than specificity, is 32cm for both sexes. Using the Intergrowth method and following the same criteria, the cutoff points are 32cm and 31.5cm for males and females, respectively. The cutoff point identified by the Fenton method (32cm) coincided with the Brazilian Ministry of Health recommendation. Adopting Intergrowth as the standard, the choice would be 32cm for males and 31.5cm for females. The study identified the need to conduct critical and on-going analyses to evaluate cutoff points, including other characteristics for microcephaly case definition.
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- 2016
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15. Association of biomarkers with atherosclerosis and risk for coronary artery disease in patients with HIV.
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Falcão Mda C, Zírpoli JC, Albuquerque VM, Markman Filho B, Araújo NA, Falcão CA, Miranda-Filho Dde B, Ximenes RA, Albuquerque Mde F, and Lacerda HR
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- Adult, Age Factors, Antiretroviral Therapy, Highly Active adverse effects, Biomarkers blood, Brazil epidemiology, Carotid Artery Diseases epidemiology, Carotid Intima-Media Thickness, Coronary Artery Disease epidemiology, Epidemiologic Methods, Female, HIV Infections drug therapy, HIV Infections physiopathology, Humans, Male, Metabolic Syndrome blood, Risk Factors, Sex Distribution, Carotid Artery Diseases blood, Coronary Artery Disease blood, HIV metabolism, HIV Infections blood
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Background: The massive use of Highly-Active Antiretroviral Therapy (HAART) in individuals with human immunodeficiency virus (HIV) coincided with an increase in cardiovascular disease, a major cause of morbidity and mortality in this group., Objective: To determine the frequency of carotid atherosclerosis and the association between biomarker levels and carotid intimal-medial thickening in HIV-positive individuals treated for HIV at referral centers in Pernambuco., Methods: This was a cross-sectional study of 122 HIV-positive patients. Subclinical carotid atherosclerosis was considered with the presence of increased intimal-medial thickness of the common carotid artery > 0.8 mm or plaques in the carotid ultrasound. The following inflammatory biomarkers were analyzed: IL6, IL1-β, TNF-α, high-sensitivity CRP, sVCAM-1 and sICAM-1., Results: Of the 122 patients analyzed, most were men (60.7%) aged > 40 years (57.4%) receiving HAART (81.1%). The prevalence of atherosclerosis was 42.6% (52 cases). Patients older than 40 years and intermediate or high Framingham score were more likely to develop atherosclerosis at the univariate analysis. Age older than 40 years (OR = 6.57, 95%CI: 2.66 to 16.2, p = 0.000), male gender (OR = 2.76, 95%CI: 1.12 to 6.79, p = 0.027) and presence of syndrome metabolic (OR = 2.27, 95%CI: 0.94 to 5.50, p = 0.070) were associated with atherosclerosis at the multivariate analysis. Elevated levels of inflammatory cytokines and adhesion molecules were not associated with the presence of atherosclerosis., Conclusion: There was no association between inflammatory biomarkers, adhesion molecules and presence of carotid atherosclerosis. However, a higher chance of subclinical atherosclerosis was observed in men, those older than 40 years, with intermediate / high Framingham score or metabolic syndrome.
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- 2012
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16. Calcium score in the evaluation of atherosclerosis in patients with HIV/AIDS.
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Monteiro VS, Lacerda HR, Uellendahl M, Chang TM, Albuquerque VM, Zirpoli JC, Ximenes RA, Albuquerque Mde F, Miranda Filho Dde B, and Sobral Filho D
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- Adult, Age Factors, Antiretroviral Therapy, Highly Active, Atherosclerosis etiology, Atherosclerosis pathology, Calcinosis etiology, Calcinosis pathology, Female, HIV Infections drug therapy, Humans, Hypercholesterolemia epidemiology, Male, Reference Values, Risk Factors, Smoking epidemiology, Atherosclerosis epidemiology, Calcinosis epidemiology, HIV Infections complications, Hypercholesterolemia complications, Smoking adverse effects
- Abstract
Background: Antiretroviral therapy has dramatically increased life expectancy in patients with HIV/AIDS although atherosclerosis has been associated with long-standing therapy., Objective: To investigate the prevalence of atherosclerosis in patients with AIDS undergoing antiretroviral therapy and the influence of different schemes and duration of treatment., Methods: HIV/AIDS patients were approached during routine consultations. Those who had been on antiretroviral therapy for at least two years had their blood collected for analysis of lipid profile and fasting glycemia and underwent cardiac CT for quantification of calcium score within six days at the most. Atherosclerosis was defined as calcium score greater than zero (CAC > 0). Traditional risk factors, metabolic syndrome and Framingham score were analyzed., Results: Fifty-three patients performed cardiac CT. Twenty-seven (50.94%) were male, mean age 43.4 years; 20.00% had hypertension, 3.77% diabetes, 67.92% hypercholesterolemia, 37.74% hypertriglyceridemia and 47.17% low HDL. Thirteen (24.53%) met criteria for metabolic syndrome and 96.23% were classified in Framingham score as "low risk." Ten patients (18.87%) were smokers. Mean duration of antiretroviral treatment was 58.98 months. Coronary atherosclerosis occurred in 11 (20.75%) patients. Duration of antiretroviral therapy was not related to atherosclerosis (p = 0.41) and there were no significant differences between different antiretroviral regimens (p = 0.71). Among traditional risk factors, smoking (OR = 27.20; p = 0.023) and age (OR = 20.59; p = 0.033) were significant in the presence of atherosclerosis. There was a trend towards a positive association of atherosclerosis with hypercholesterolemia (OR = 8.30; p = 0.0668)., Conclusion: Factors associated with atherosclerosis were age, smoking and hypercholesterolemia. Duration and type of antiretroviral therapy had no influence on the prevalence of atherosclerosis.
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- 2011
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17. Profile of patients with hypertension included in a cohort with HIV/AIDS in the state of Pernambuco, Brazil.
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Arruda Júnior ER, Lacerda HR, Moura LC, Albuquerque Mde F, Miranda Filho Dde B, Diniz GT, Albuquerque VM, Amaral JC, Monteiro VS, and Ximenes RA
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- Acquired Immunodeficiency Syndrome drug therapy, Adult, Anti-HIV Agents therapeutic use, Body Mass Index, Brazil epidemiology, Chi-Square Distribution, Cohort Studies, Cross-Sectional Studies, Female, Humans, Hypertension classification, Lipodystrophy epidemiology, Male, Obesity epidemiology, Reference Values, Risk Factors, Acquired Immunodeficiency Syndrome epidemiology, Hypertension epidemiology, Life Style
- Abstract
Background: Hypertension (HBP) is modifiable risk factor, whose control may reduce cardiovascular disease in patients with human immunodeficiency virus (HIV)., Objective: To estimate the prevalence of hypertension and describe the characteristics of patients with hypertension infected by HIV/AIDS., Methods: A cross-sectional study aligned to a cohort of patients with HIV/AIDS. The study considered hypertension at levels > 140/90 mmHg or use of antihypertensive drugs and pre-hypertension at levels > 120/80 mmHg., Results: Out of 958 patients, 388 (40.5%) were normotensive, 325 (33.9%) were pre-hypertensive, and 245 (25.6%) were hypertensive. Out of these 245 patients, 172 (70.2%) were aware of the fact there they were hypertensive, and 36 (14.8%) had blood pressure controlled. Sixty-two (62) patients (54.4%) were diagnosed with hypertension after HIV diagnosis. Lipodystrophy occurred in 95 (46.1%) patients; overweight/obesity in 129 (52.7%). Use of antiretrovirals occurred in 184 (85.9%), 89 (41.6%) with protease inhibitors (PI) and 95 (44.4%) without PI. Out of these patients, 74.7 used antivirals > 24 months. Age, family history of hypertension, waist circumference, body mass index and triglyceride levels were higher among hypertensive patients. Time of HIV infection, CD4 count, viral load, time and type of antiretroviral regimen were similar in hypertensive and prehypertensive patients., Conclusion: The high frequency of uncontrolled hypertensive patients and cardiovascular risks in HIV-infected patients point out to the need for preventive and therapeutic measures against hypertension in this group.
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- 2010
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18. [Mortality trend due to accidental tetanus from 1981 to 2004 in Pernambuco and analysis of the impact on intensive care unit attendance].
- Author
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Gouveia PA, Silva CE, Miranda Filho Dde B, Bernardino SN, Escarião AG, and Ximenes RA
- Subjects
- Adolescent, Adult, Age Distribution, Brazil epidemiology, Child, Female, Humans, Male, Middle Aged, Retrospective Studies, Sex Distribution, Tetanus therapy, Young Adult, Hospital Mortality trends, Intensive Care Units statistics & numerical data, Tetanus mortality
- Abstract
Despite reductions in the incidence of accidental tetanus cases in Brazil, there has not been any significant decrease in its mortality. In this case series, the mortality rates before and after establishing standard management practices for tetanus patients in the intensive care unit at the Oswaldo Cruz University Hospital are compared over the period from 1981 to 2004. Over these 24 years, 1.971 patients were admitted. Before establishing the intensive care unit management, the mortality rate was 35%. The Intensive care unit for attending to tetanus patients was established in 1997. From 1998 to 2004, the mortality rate fell to 12.6%: OR = 0.27 (95% CI = 0.18-0.39); p < 0.001. This trend was seen in all age groups and both sexes. The centralization of attendance for these patients into a single specialized service with early treatment in an intensive care unit has therefore been decisive in reducing the mortality rate. This service can count on the medical team's vast experience of tetanus management, with better treatment of symptoms that forestalls the serious complications from this disease.
- Published
- 2009
- Full Text
- View/download PDF
19. [Importance of cerebrospinal fluid control tests in bacterial meningitis cases as a discharge criterion].
- Author
-
Cabral DB, Bezerra PC, Miranda Filho Dde B, and Mendizabal Mde F
- Subjects
- Adolescent, Adult, Aged, Female, Humans, Male, Meningitis, Bacterial drug therapy, Middle Aged, Predictive Value of Tests, Reference Values, Meningitis, Bacterial cerebrospinal fluid, Patient Discharge
- Abstract
There is controversy regarding indications for cerebrospinal fluid control tests on patients who have clinically recovered from bacterial meningitis, as a cure criterion. Some authors advocate discharge after confirmation of clinical and cerebrospinal fluid normalization, while others maintain that cerebrospinal fluid analysis is not justified in all cases. This case series with group comparisons investigated changes seen in cerebrospinal fluid control tests and evaluated the importance of this for the discharge decision. Out of 297 patients studied, the cerebrospinal fluid control test did not change the discharge intention in 89.9% of the cases (healed cerebrospinal fluid), while in 10.1%, the discharge was suspended (non-healed cerebrospinal fluid). Of these, the antibiotic scheme was changed in 30%. Among the variables that might predict the presence of non-healed cerebrospinal fluid on admission, cerebrospinal fluid protein levels higher than 100mg/dl (p = 0.04) and glycorrhachia lower than or equal to 20 mg/dl (p = 0.03) were associated with a 2.5-times greater chance. These may be useful as criteria for indicating cerebrospinal fluid control tests before discharge.
- Published
- 2008
- Full Text
- View/download PDF
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