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Background: Aquatic exercises have become a very important therapeutic option for chronic venous disease (CVD). There is evidence in the literature showing that this type of exercise is a mechanism that improves venous return and is important in vascular reeducation. These exercises also help to reduce the venous hypertension caused by CVD, improving patients' quality of life. Objectives: To analyze the effects of aquatic exercises on the quality of life of patients with CVD. Methods: This was a longitudinal, prospective, interventional pilot study conducted with 16 people with CVD classified from C1 to C5. Participants were assessed at baseline using a data collection form and administration of two quality of life questionnaires, the SF-36 (Generic) and the AVVQ-Brazil (CVD-specific), and an Analog Visual Pain Scale (AVPS). They then undertook a program of 10 sessions of aquatic exercises, three times per week. The quality of life questionnaires and the AVPS were administered once more after all sessions had been conducted. Results: The data collected were subjected to statistical analysis to a significance level of p < 0.05. Patients exhibited improved quality of life as measured by the SF-36 in the domains Physical functioning, Physical role limitation and Pain (p < 0.05). The patients' pain levels reduced after treatment according to the AVPS (p = 0.007). Only scores for the Pain and dysfunction domain of the AVVQ-Brazil questionnaire exhibited significant improvement (p = 0.013). Conclusions: Aquatic exercises were capable of improving aspects of quality of life and of reducing pain, demonstrating that they benefit patients with CVD. [ABSTRACT FROM AUTHOR]