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The urban space, constituted through a space-time relationship as a product of socio-spatial processes, presents itself as dynamic and multifaceted due to the capitalist production model that imposes on society transformations from global to local. Nevertheless, spatial processes are observed that, from the point of view of the internal structure of cities, confer changes in the production of space, especially with regard to commercial and service activities. In this sense, the present study was developed from observations of the transformations that occurred in the intra-urban space of Uberlândia (MG). Among the recent dynamics that occurred in the city, it was observed the consolidation of new centralities, especially Avenida João Naves de Ávila, considered a commercial axis, through the analysis and identification of spatial patterns resulting from the densification of commercial and service activities, as a reflection of the spatial process of decentralization. Based on this assumption, the research has as main objective to analyze the process of decentralization and the formation of new centralities from the commercial axes of the city of Uberlândia, having as a cutout Avenida João Naves de Ávila and using the methodology of Ribeiro Filho (2004), from which 129 blocks could be identified in their entirety, with different and large numbers of tertiary activities. After analyzing the data, it was observed that the decentralization of tertiary activities is still in progress on the avenue, resulting in different degrees of functional intensity, as well as in the establishment of distinct patterns of location of commercial and service activities. In this sense, six sectors were classified: Central I, Central II, Special, East I, East II and Far East, being heterogeneous among themselves, but with characteristics that make them singular. [ABSTRACT FROM AUTHOR]