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This article aims to understand the urban-regional space from the action of agents who coordinate the real estate production of Latin American metropolises. The procedural orientation followed the methodology of the bibliographic research and data surveys, having as reference the main Latin American journals of urban and regional studies. The four metropolises considered the most global in Latin America were investigated based on the criterion of the presence of "Oficinas Premium", in order to understand how it happened and what the consequences of the formation of the global space were. After a brief definition of some terms, the scenarios that made Mexico City, São Paulo, Santiago and Buenos Aires the main global cities in Latin America are presented. The article ends with notes related to the restructuring of urban centers, the horizontal expansion of the city, population dynamics, and the action of the public authorities and the worsening of inequalities as a result of this globalization process. [ABSTRACT FROM AUTHOR]