Subjective well-being is a theme which analyzes how people evaluate satisfaction in life, taking into account personal aspects, experience, values and expectations. Current paper identifies subjective welfare and autonomy in home-office of university professors during the COVID-19 pandemic through a transversal study and quantitative approach. A sample of fifty-four university professors from a university in southern Brazil was generated by applying the Subjective Welfare Scale by Albuquerque and Tróccoli (2004), divided into positive and negative aspects, satisfaction with life, to which was added a dimension called autonomy in home-office during the COVID-19 pandemic. Results show that most professors (68.51%) showed a moderate subjective wellbeing, with negative aspects higher than the positive ones, or rather, 16.66% and 14.81%, respectively. High autonomy in home-office with 66.67% of replies has been reported. Results are satisfactory since, even though negative aspects are more present than the positive ones in subjective well-being, the professors are committed and try to perform their activities in the best way possible. This is a determining factor for institutions which are trying to make adaptations since people are the most important active goods of the organization. [ABSTRACT FROM AUTHOR]