Search

Copyright of Review of Medicine / Przeglad Lekarski is the property of Wydawnictwo Przegld Lekarski / Publisher Medicine Review and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The article deals with Romanian libraries as information and multimedia centers at different level of education. The libraries and documentation centers were visited by the authors during a seminar in Sibiu between Sep. 27 and Oct. 4, 2014. The article presents the history, collections and the mission of the provincial ASTRA public library, affiliated with Lucian Blaga Central University Library. A particular attention is given to school Documentation and Information Centers – a new form of library services. These centers have been established to equalize chances for pupils from rural areas and to help members of the public get better adjusted to modern life conditions by teaching them basic skills in core capacities relative to modern forms of information delivery.

Clostridium difficile pathogen is a cause of the most frequent nosocomial infection, which is antibiotic-associated diarrhea. Antibiotic treatment causes disruption of the microbiome balance, which makes the gut a friendly environment for the pathogen. It leads to pseudomembranous colitis, toxic megacolon and even death. Clostridium difficile infection (CDI) is particularly dangerous to elderly patients, leading to the highest mortality rate. C. difficile is equipped with many virulence factors such as toxin A and B, binary toxin CDT, flagellum, S- -layer proteins, Cwp66 and GroEL proteins, protease Cwp84, fibronectin-binding protein and the ability to form biofilm and spores. Problems with anti-CDI therapy prompt researchers and clinicians to seek alternative ways of therapy. Identification of immunological epitopes in outer layer proteins and the use of them as antigens for anti-CDI vaccines would be a rational approach to prevent the disease, but unfortunately such vaccines are not available yet. In this article we review the course of the disease, virulence and risk factors. We summarize briefly epidemiological data and the latest achievements in CDI treatment. [ABSTRACT FROM AUTHOR]

Recent studies have shown increasing incidence, severity, and recurrence rates of Clostridium difficile infection (CDI). There has been a startling shift in the epidemiology of CDI over the last decade worldwide, and it is now increasingly recognized as a cause of diarrhea in the community. Classically considered a hospital-acquired infection, it has now emerged in populations previously considered to be low-risk and lacking the traditional risk factors for C. difficile infection. Recent studies have demonstrated great genetic diversity for C. difficile. Symptomatic patients and asymptomatic carriers, animals, plants, water, food and hospital environmental may play an important source in these infections, apart from the role play in spore dispersal. This review focuses on the epidemiology, increasing importance, source infectious and virulence factors of C. difficile. [ABSTRACT FROM AUTHOR]

Recent studies have shown increasing incidence, severity, and recurrence rates of Clostridium difficile infection (CDI). There has been a startling shift in the epidemiology of CDI over the last decade worldwide, and it is now increasingly recognized as a cause of diarrhea in the community. Classically considered a hospital-acquired infection, it has now emerged in populations previously considered to be low-risk and lacking the traditional risk factors for C. difficile infection. Recent studies have demonstrated great genetic diversity for C. difficile. Symptomatic patients and asymptomatic carriers, animals, plants, water, food and hospital environmental may play an important source in these infections, apart from the role play in spore dispersal. This review focuses on the epidemiology, increasing importance, source infectious and virulence factors of C. difficile. [ABSTRACT FROM AUTHOR]