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1. [Contemporary opinions on pathogenesis, genetics and clinical picture of laterality disorders - left-right axis development defects].

Author

Misiak B and Smigiel R

Subjects
Brain embryology, Functional Laterality, Humans, Infant, Newborn, Situs Inversus diagnosis, Situs Inversus embryology, Situs Inversus genetics, Syndrome, Brain abnormalities
Abstract

Congenital malformations pose a great challenge to all medical specialities. Laterality defects belong to the group of congenital anomalies resulting from left-right axis development disturbances which arise at an early stage of embryogenesis. The authors discuss selected embryological, epidemiological, genetic and clinical aspects of left-right axis malformations. Furthermore recent knowledge concerning new genes involved in left-right asymmetry development is presented.

Published
2009

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