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1. [The importance of examining genetic polymorphism of drug oxidation in psychiatry].

Author

Beszłej JA and Kiejna A

Subjects
Biotransformation, Cytochrome P-450 Enzyme System metabolism, Humans, Isoenzymes, Liver enzymology, Mephenytoin metabolism, Metabolic Diseases diagnosis, Oxidation-Reduction, Phenotype, Sparteine metabolism, Cytochrome P-450 Enzyme System physiology, Polymorphism, Genetic genetics, Psychiatry
Abstract

The paper describes: 1. Drug oxidation process. 2. Cytochrome P-450 Isozymes. 3. Genetic polimorphism of drug oxidation. 4. Spartein test. Metabolic ratio, extensive and poor metabolizers. 5. Cytochrom P-450 and drug metabolism. 6. Inhibition of drug oxidation process and inhibitors of CYP450. 7. Influence of CYP450 genetic polimorphism on development of diseases. 8. Clinical value of examining the genetic polimorphism of drug oxidation in psychiatry.

Published
1995

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