1. [Radioimmunotherapy in patients with ovarian cancer in complete remission after the first line surgery and chemotherapy after second look laparoscopy procedure].
- Author
-
Markowska J, Madry R, Kierzkowski J, Malicki J, Roszak A, Lubin J, and Bratos K
- Subjects
- Female, Humans, Remission Induction, Retrospective Studies, Time Factors, Treatment Outcome, Antibodies, Monoclonal therapeutic use, Iodine Radioisotopes therapeutic use, Laparoscopes, Ovarian Neoplasms radiotherapy, Ovarian Neoplasms surgery, Radioimmunotherapy methods, Second-Look Surgery instrumentation
- Abstract
Objectives: The aim of the study was analysed a chance to successful radioimmunotherapy in patients with ovarian cancer as a consolidation procedure., Design: Between 2000 and 2002 we introduced 56 patients into consolidation study with radioimmunotherapy after second look laparoscopy., Materials and Methods: 17 patients during screening procedure have failed--mostly with positive CT scans (9/17). We have done 39 laparoscopies. Among 11 patients during laparoscopy we have found in 6 cases a residual disease and in 5 cases adhesions in abdomen or pelvis and this group was excluded from study. The remaining 28 patients were divided into two groups--14 in active and 14 in control arm., Results: Only 50% of patients with ovarian cancer in complete clinical remission after first line surgery and chemotherapy can be candidates to consolidation therapy. Among patients subjected to laparoscopy in 70% there was no evidence of macroscopic disease and adhesions., Conclusions: Only 50% patients in complete clinical remission after first line surgery and chemotherapy have chance to successful radioimmunotherapy.
- Published
- 2003