1. [Intramedullary spinal cord cavernous malformations--clinical presentation and optimal management].
- Author
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Ungeheuer D, Stachura K, and Moskała M
- Subjects
- Adult, Female, Hemangioma, Cavernous, Central Nervous System complications, Hemangioma, Cavernous, Central Nervous System epidemiology, Hemangioma, Cavernous, Central Nervous System surgery, Hemorrhage epidemiology, Hemorrhage etiology, Humans, Male, Middle Aged, Neurosurgical Procedures, Risk, Spinal Cord pathology, Spinal Cord Neoplasms complications, Spinal Cord Neoplasms epidemiology, Spinal Cord Neoplasms surgery, Treatment Outcome, Hemangioma, Cavernous, Central Nervous System diagnosis, Spinal Cord Neoplasms diagnosis
- Abstract
Spinal cord cavernous malformations (scCM) are rare vascular malformation representing approximately 5-12% of all intramedullary lesions. The authors reviewed over 20 publications available and have consolidated existing knowledge on the pathology, epidemiology, clinical and radiological characteristics scCM. scCM management and treatment methods have been outlined concisely and achieved outcomes have been presented. The average age of onset is 42 years without sexual predilections. scCM statistically most commonly occur in the thoracic region--57%, in 9% of patients familiar prevalence is present, in 27% of patients the co-existence of intracerebral vascular malformation is diagnosed. The most common clinical symptoms are the sensory and motor deficits (respectively 65% and 63%). The course of the disease in 54% of cases, is a progressive, slow neurologic deterioration, although it is also observed a rapid onset associated with cavernoma hemorrhage. The risk of hemorrhage is estimated at 2.5% annually. scCM that are located intramedullary, are asymptomatic should be the subject to observation. Cavernomas that are symptomatic, having contact with the surface of spinal cord or exophytic should be subject to surgical treatment that is intended to complete removal. Results of surgical treatment are satisfactory, in about 60% of patients clinical improvement has been observed.
- Published
- 2015