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The prevalence of chronic kidney disease (CKD) in the world is constantly increasing. This is related to the eldering of the societies, growing numbers of patients with diabetes, hypertension, atherosclerosis and obesity. The progress of the disease increases the risk of complications and mortality, especially from cardiovascular causes and leads to end-stage renal disease requiring renal replacement therapy. The analysis involving 1452 patients (762 women and 690 men aged 57.4 years ± 19.8 years) from the Emergency Department in Kielce revealed reduced eGFR below 60 ml/ min/1,73 m2 in 474 (32.6%) of participants and mean values of eGFR was 68.6 ± 22.3 ml/min/1.73 m2. Such high percentage of patients fulfilling criteria of CKD may be due to the fact that to the Emergency Department coming patients with high comorbidity and with increased risk of kidney disease.

Methods of testing products made of plastics in medicine do not take into account chemico-toxicological evaluation of biomaterials made of fibres or of foam plastics. According to the project of the monograph Compendium Medicamentorum COMECON, water extracts should be used, where the is proportion would be maintained: 30 g of biomaterial in 100 cm3 of water. The proportion, in case of products with well-developed surface, does not ensure that the material is wholly immersed in fluid. Therefore studies were made on the use of lower concentration of the material in water, with on the other hand, extraction time being prolonged. Summing up, the authors suggest, with regard to grafts, use of the following conditions of water extraction: temperature 120 degrees C, duration 60 min. proportion of the studied material in the amount of distilled water 1:10.