1. Outbreak of Clostridioides difficile infection in Silesian district hospital
- Author
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Klaudia T. Szarek, Monika A. Kabała, Krzysztof Sacha, Franciszek Drzymała, Adam Borek, Monika Pomorska-Wesołowska, Małgorzata Aptekorz, and Gayane Martirosian
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clostridioides difficile infection ,outbreak ,clostridioides difficile toxins ,Pharmacy and materia medica ,RS1-441 ,Dentistry ,RK1-715 - Abstract
INTRODUCTION: In order to evaluate a Clostridioides difficile infection (CDI) outbreak between December 2018 and February 2019 in the internal medicine ward of a district hospital in Silesia, 6 stools from 5 patients were examined. MATERIAL AND METHODS: C. difficile was identified, genes encoding glutamate dehydrogenase (GDH) – gluD, A/B – tcdA/tcdB and binary – cdtA/cdtB toxins, ermB were determined by mPCR and antibiotic resistance by means of E-Tests. RESULTS: Women predominated among the patients (4/5). All the 6 C. difficile isolates belonged to hyperepidemic ribotype 027, were positive for all genes and were resistant to moxifloxacin, erythromycin, clindamycin, rifampicin, imipenem, and chloramphenicol. CONCLUSIONS: The obtained results indicate that the hyperepidemic C. difficile clone is spreading in the ward.
- Published
- 2023
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