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Background: Numerous studies have examined the effect of cognitive therapy based on mindfulness and the study of coping strategies, depression, and suicidal ideation. However, there is a research gap in the study of the effect of cognitive-based cognitive-cognitive therapy on cognitive coping strategies, depression, and students' suicidal thoughts. Aims: To investigate the effect of cognitive-based cognitive-cognitive therapy on coping strategies, depression and students' suicidal thoughts. Method: The research was semi-experimental with pre-test-post-test design with control group. The statistical population of the study was all male and female undergraduate students of Payame Noor University of Kermanshah in the second semester of 2018-2019. 24 students were randomly selected as a sample and randomly assigned to two experimental and control groups (12 people). The research instruments included: Lazarus and Volkman (1984) coping strategies questionnaires, Beck's second edition of Depression (1996), Beck's Suicidal Thought (1979) and mindfulness-based cognitive therapy sessions (Van Soon, Niklik, Pop, and Pop & Power, 2011). Data were analyzed using multivariate analysis of covariance. Results: Mindfulness-based cognitive therapy significantly reduced students' emotion-driven strategies, depression, and suicidal ideation (P< 0/01). Conclusions: Students who participated in cognitive, mindfulness-based cognitive therapy sessions scored lower on coping strategies, depression, and suicidal ideation.