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Start Over Descriptor "Cardiac markers" Language persian
2 results on '"Cardiac markers"'

1. Evaluation of cardiac markers and some serumic biochemical parameters in seropositive horses with equine influenza

Author

ali hassanpour, bahram amouoghlitabrizi, and mansour khakpour

Subjects
Equine influenza, Cardiac markers, Biochemical parameters, Horse, Veterinary medicine, SF600-1100
Abstract

Abstract This study was performed to evaluate the effect of influenza in horses on the electrocardiogram changes, cardiac arrhythmias and concentration of cardiac troponin in serum and serumic activity of some enzymes. After electrocardiography and count heart rate, blood samples were taken from jugular vein in 202 stallions (1-3 years). After centrifugation, the serum was removed and then seroprevalence of equine influenza was investigated by ELISA method. From 202 horses, 19 samples (9.5%) were positive and 183 samples (90.5%) were negative and these horses were put in deseased and healthy groups, respectively. In all samples cardiac troponin I, liver enzymes, total protein, albumin, glucose, urea, creatinin, cholesterol and triglyceride in the serum were measured. The electrocardiograms of all the horses were taken and the kind of cardiac arrhythmias were recorded. Average heart rate increased significantly in diseased group (p< 0.05). Occurrence of cardiac arrhythmias was significantly greater in diseased group (p< 0.05). Changes in QRS complex were significant in diseased group. The serumic concentration of cardiac troponin I increased significantly (p= 0.023). The difference mean of liver enzymes was not significant between two groups exept for alkaline phosphatase. In diseased group the mean of total protein and albumin increased significantly (p= 0.046 and p= 0.021, respectively) but, glucose and cholesterol decreased nonsignificantly. The mean difference of urea, creatinin and triglyceride was nonsignificant between the two groups. The end result was that following equine influenza some electrocardiographic changes were created in horses most of which are physiologic changes and the concentration of cardiac troponin I, total protein, albumin and liver enzymes in are increased.

Published
2013

2. A comparative study of rapid test and routine methods for the measurement of cardiac markers in patients with suspected acute myocardial infarction

Author

gholamreza Shahsavari, khatereh Anbari, nastoh Dehkourdi, and masoume Jalalvand

Subjects
lcsh:R5-920, lcsh:R, cardiovascular system, lcsh:Medicine, cardiovascular diseases, Immunochromatography, Cardiac markers, Acute myocardial infarction, lcsh:Medicine (General)
Abstract

Background : In many patients with chest pain, the correct diagnosis of acute myocardial infarction(AMI) is dependent mainly on the measurement of cardiac markers such as cardiac creatin kinase isoenzyme (CK-MB) and cardiac troponin I (cTnI) ,because the electrocardiogram is often non-diagnostic. The measurement of cardiac markers are superior for the detection of minor myocardial injury and more-accurative diagnosis. The purpose of this study was to evaluate the assay of routin method of CK-MB and cTnI in comparison with rapid test method in suspected patients to AMI. Materials and Methods: The study population comprised 142 patients admitted to the emergency ward with acute chest pain for less than 12 hours before admission. Venous blood specimen were obtained to measure CK-MB and cTnI rapid assay tests with Acon and Golden kits, and Elisa cTnI and photometry CK-MB assays. Results: The results of Elisa cTnI assay had 52 positive and 90 negative patients compared to Golden cTnI rapid test, 27 positive and 110 negative patients, while in comparison with Acon cTnI rapid test there were 30 positive and 112 negative patients ( p≤ 0.001). The results of photometry CK-MB assay had 39 positive and 103 negative patients compared to Golden CK-MB rapid test which had 60 positive and 77 negative patients( p ≤ 0.001), while in comparison with Acon CK-MB rapid test in had 78 positive and 64 negative patients ( p ≤ 0.035). Relative sensitivity and relative specificity were compared to routne metohs: for the Golden rapid cTnI test were 50% and 98.8% respectively for Acon rapid cTnI test 51.9% and 96.6%, for Golden rapid CK-MB test 69.2%/ and 63.1°/o, and for Acon rapid CK-MB test 69.2% and 50.4% . Conclusion: The present results showed that the rapid cTnI test is very specific but not sensitive for AMI diagnosis while rapid CK-MB test is neither sensitive nor specific for AMI dignosis in patients with acute chest pain.

Published
2014

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