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Background and Objective: Hypotension is a common complication of cesarean section with spinal anesthesia, which can be dangerous for both mother and neonatal. The aim of this clinical trial study was to investigate the effect of using bandaging on the lower limbs in preventing of post spinal hypotension in cesarean section. Materials and Methods: This prospective clinical trial study was performed in 2019-2020 at Fatemieh Hospital in Hamadan. A total of 64 patients undergoing cesarean section with spinal anesthesia were randomly divided into two groups of with bandaging at the time of surgery and without bandaging. Demographic information, hemodynamic status in the first hour after spinal anesthesia, hypotension, nausea and vomiting, bradycardia, tachycardia, atropine levels, ephedrine consumed, was compared in both groups. The data were statistically analyzed by SPSS version 16 software and analyzed. Results: The mean age of both groups of patients was approximately 30 years (P = 0.958). Hypotension (25 vs. 78.1%), bradycardia (9.3 vs. 15.6%) and intraoperative nausea and vomiting (12.5 vs. 59.4%) in the intervention group with significantly less than the control group. The amount of ephedrine (4.1 3 3.1 vs. 20.6 13 13.2 mg) was lower in the intervention group than in the control group (P = 0.01). In the study of hemodynamic status of systolic and diastolic pressure from 2 to 6 minutes and mean arterial pressure from 2 to 10 minutes after spinal with a significant difference in the intervention group was more than the control group (P