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Introduction: Psoriatic Arthritis (PSA) is an inflammatory musculoskeletal disorder characterized by significant dysfunction in synovial tissue, tendons and axial sites. PSA is associated with metabolic comorbidities such as diabetes, obesity, congestive heart failure, fatty liver disease, depression and/or anxiety. Due to differences in the clinical manifestations of PSA, some patients are not diagnosed through clinical examination. Delayed psoriatic arthritis diagnosis or consultation has been related to low quality of life and increased frequency of comorbidities and persistent inflammatory state. The aim of the present study was to explore multiple etiologies of PSA, screening tools, and pharmaceutical therapy. Articles were searched from international databases including Magiran, Scopus, Google Scholar, PubMed, and Springer. The keywords of Psoriatic Arthritis, Screening tools, pathogenesis, treatment, and Biomarkers were used to extract articles. Conclusion: Our study showed that heterogeneity in the etiology of PSA was a major reason for classification problems within this disease spectrum. The explanation for this disease heterogeneity may be focused on variations in genetic and environmental factors. Screening strategies (ex: CASPAR criteria and biomarkers) are a significant first step in early treatment. Moreover, many types of therapy are available to help decreased joint problems, muscle weakness, and disease severity. Detection of dependent factors related to PSA might help in the early intervention of these patients to address clinical and para-clinical issues. Here we have provided an updated review of the early diagnosis, clinical features, pathogenesis, screening tools, biomarkers, and treatment recommendations, such as new biologic medications, for Psoriatic Arthritis.

Background and Objectives: Rheumatoid arthritis is one of the most common diseases of the immune system which is increasing rapidly. The results of the recent literature review confirm the roles of stress and psychosocial stressors on physiological mechanisms, such as psychoneuroimmunology, as causal factors leading to the development of rheumatoid arthritis. Considering the effectiveness of psychological problems in the development of this disease, the present study was conducted to compare the effectiveness of coping therapy and cognitive-behavioral therapy in cognitive immunity and psychological well-being indicators of patients with rheumatoid arthritis referring to Imam Khomeini Hospital, Tehran, Iran. Methods: This was a quasi-experimental study with a pretest-posttest control group design. In the present study, the effectiveness of two independent variables (i.e., coping therapy and cognition-behavioral therapy) on dependent variables (i.e., immune-cognitive and psychological well-being indicators) was examined. The statistical population consisted of patients with rheumatoid arthritis referring to Imam Khomeini Hospital from March-August in 2019. The final sample (n=60) was selected by the purposive sampling method and the subjects were randomized into two groups of experimental and control (n=20 each). Subsequently, the experimental group was subjected to coping therapy and cognitive-behavioral therapy interventions. The instruments used in the present study included Psychological Welfare Scale, C-reactive protein (CRP) immunological indicators test, and erythrocyte sedimentation rate (ESR) test. The collected data were analyzed using the analysis of covariance model. Results: The results of the analysis of covariance model were indicative of a p-value of < 0.05 as significant. Moreover, it was found out that the effectiveness of coping therapy and cognitive-behavioral therapy on CRP, ESR, psychological well-being was significant (P

Background: Pain Catastrophizing and pain anxiety are important variables in chronic pain perception, but little is known about their role in pain intensity in patients with rheumatoid arthritis. Aims: The purpose of this study was to investigate the role of pain catastrophizing and pain anxiety in predicting pain intensity in women with rheumatoid arthritis. Method: This study was a correlational study. From women with rheumatoid arthritis referring to Imam Khomeini Hospital and private clinics in Tehran, 100 patients were selected using convenience sampling method. Instruments used in this study included the Pain Catastrophizing Scale (Sullivan et al, 1995), the Pain-Anxiety Symptom Scale (McCracken et al, 1996), and the Visual Analogue Scale. Results: The results showed that pain catastrophizing and pain anxiety significantly predicted pain intensity in women with rheumatoid arthritis. The standardized regression coefficient for pain catastrophizing was 0/51 (P

Objective: The aims of this study are scoring the educational wards of Imam Hospital complex, comparison of different wards according to educational, research and treatment scores and finally improvement of hospital's curriculum.Methods: For assessing the educational performance a questionnaire was filled by the wards' directors. Another questionnaire was filled by faculty members in order to evaluating the research situation of the ward. Customers' satisfaction was assessed through questionnaires which were filled by residents, interns, students and patients. Data were analyzed using SPSS-13.Results: In educational sector, pediatric ward has the first rank, infection ward the second rank. In the research sector infection ward the first and the pediatric ward have the second rank. Training customers have the most satisfaction of general ward and Patient had more satisfaction of surgery ward (3 and 4 surgery ward).With 47% score to training sector, 28% to research sector and 25%to satisfaction, the infection ward has the first rank, pediatric ward second rank and orthopedic ward the third rank of Imam Khomeini complex.Conclusion: In Imam Khomeini complex survey of wards ranking, the infection ward has the first rank pediatric ward second rank and orthopedic ward the third rank in overall survey.