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Idealism as a motivating factor can pave the way for the development of human societies, especially in rural areas. Therefore, the main purpose of this paper is to analyze the effects of idealism on rural development in the Sistan region. This research is based on the descriptive-analytical method and is applied in terms of purpose. Documentary and survey methods were used to collect information. The sample size per village unit was determined using the Sharp correction formula of 40 villages. According to Cochran's formula, the sample size for the head of the household unit was 381. The validity of the researcher-made questionnaire was confirmed by experts on the subject, and the reliability coefficient was 0/856. Spearman correlation coefficient, analysis of variance and taxonomic methods were used to investigate the effects of rural idealism on rural development. The results of the taxonomy of development by leveling rural idealism showed that the highest number in both levels is in the middle group. The results of the evaluation of idealism showed that Jalehie village in Zabol city (124/08) had the highest and Kang Emamdad village in Hirmand city (66/33) had the lowest level of idealism. Also Karbasak village from Zabol city (3/66) had the highest and Akondzad village of Hirmand city (1/86) had the lowest level of rural development and the overall result of the study showed that there is a significant relationship between idealism and the level of rural development in the villages of Sistan region (with sig 0/000). [ABSTRACT FROM AUTHOR]

In this paper, integrated production and batch delivery scheduling problem for make to order production system and one customer in supply chain has been addressed. One manufacture received n orders from one customer. Orders must be processed by single machine and sent in batches to customer. Sending several jobs as a batch leads to less transportation cost but may increase the cost of tardiness jobs. The objective is determining the production and delivery scheduling so that the related costs is minimized. The problem is strongly NP-hard. In this paper, one new math programming model including Mixed Integer Programming (MIP) model, Ant Colony System (ACS) and Elastic Ant System (EAS) are presented for solving it. In order to evaluate the efficiency of these two methods computational tests based on full factorial experimental design has been conducted. Computational test is performed for evaluation of these methods. The obtained results show that the heuristic algorithm is efficient which has been verified by using. Analysis of variance (ANOVA) technique. The results showed that the ACS is the most efficient method. [ABSTRACT FROM AUTHOR]

Background and aim: Dental caries is a major health problem nowadays. polyphenolic compounds of tea can exert its anti-cariogenic effects by affecting the cariogenic Streptococcus Mutans bacteria. The aim of this study was to investigate the antimicrobial effect of ethanolic, methanolic and aqueous extracts of green tea in comparison with chlorhexidine on Iranian strain of this bacteria. Materials and Methods: 10 g of green tea powder was dissolved in 100 mg of ethanol, methanol and aqueous solvents separately. After one week, the obtained solutions were filtered and 100mg / ml solution was extracted. to evaluate the diameter of inhibition, zone The Swabs impregnated with suspension scrubbed on culture medium. the extracts were injected onto special paper discs and the impregnated disks were placed on the bacterial culture media, plates were kept in the incubator for 24 hours at 37 °C and then the diameter of inhibition zones was calculated. Using Muller Hinton Broth, herbal extracts were made at concentrations 1:2 (50 mg/ml) and 1:4 (25 mg/ml) and 1:8 (12.5 mg/ml) and 1:16 (6.25 mg/ml) and 1:32 (3.125 mg/ml). Then, 100 μl microbial suspensions made by standard McFarland 0.5 were transferred to all test tube. The test tubes were placed in an incubator at 37°C for 24 hours. After 1 day, contents of all test tubes were separately cultured on Muller Hinton Broth medium. The culture media were incubated at 37°C for 1 day. The results were evaluated in the form of growth or non-growth of bacterial colonies on culture media and MBC and MIC were determined. ANOVA and Post hoc test was used for statistical analyze with SPSS Software. Results: Experimental results after three iterations showed mean values of 16.16, 16.66, 12.5 and 17.5 mm for diameter of the inhibition zone of ethanolic, methanolic and aqueous extracts and chlorhexidine 0.2%, as control. Also, at the significant level of 0.05, there was no significant difference between the diameter of the inhibition zone of ethanol, methanol and chlorhexidine extracts. (p>0.05)The Aqueous Extract Showed Significant difference with other Extracts. MBC Reported 12.5mg/ml for Ethanolic and 50mg/ml for two other extracts. MIC Reported 6.25mg/ml for ethanolic and 25mg/ml for two other extracts. Conclusion: The results showed that the antimicrobial effects of ethanolic and methanolic extract of Iranian green tea are higher than aqueous extract and there is no significant difference between these two extracts with Chlorohexidine. [ABSTRACT FROM AUTHOR]

In this paper, the analysis of variance (ANOVA) of weld residual stress distribution (using the hole drilling strain gage method according to ASTM 837 standard) was investigated (in the hoop and axial direction of the 56-inch gas transmission). The results of ANOVA show that the best distribution curve of residual stress is the third order function (3 degree of freedom) in the distribution diagram of hoop and axial residual stresses. In this order, the p value of the hoop and axial residual stress is 0.044 and 0.001, respectively. This indicates the high reliability of the third order function. Also, the value of F and coefficient of determination of this order has an appropriate value. In addition, due to the high p value and low reliability, the 5-order approximation function is not a suitable residual stress distribution curve compared to the third order function. Order approximation functions (2 and 4) have lower reliability (higher p value) and lower F value than odd order (3 and 5). Despite having the highest freedom with the highest p (lowest reliability), the lowest F, and the lowest coefficient of determination, the second-order function, is the most inappropriate approximation function. Despite the existence of residual stress with respect to the zero experimental residual stress compared to the approximation function, the use of strain test in points far from the weld one and the base metal is not essential. [ABSTRACT FROM AUTHOR]

Introduction: Periodontitis is an inflammatory disease with microbial etiology; furthermore Diabetes is a metabolic disease characterized by hyperglycemia, considering Candida albicans is an opportunistic fungus that can lead to candidiasis infection; The aim of this study is to comparing the average number of colonies of candida albicans in gingival sulcus fluid in diabetic and non-diabetic patient with chronic periodontitis. Materials & Methods: This case control study included 60 patient aged 40-60 years that leave in 4 group composed 15 individuals each group: healthy subjects, diabetic without periodontitis, non-diabetic with periodontitis and diabetic with periodontitis patients. Samples were acquired using sterile paper points from gingival sulcus and centrifuged, then cultured on chrome agar medium and incubated. Number of colonies were counted and analyzed with ANOVA and LSD tests. Results: Counting number of colonies in different groups showed, in healthy subjects, 33.3 percent with mean 4.2 colonies and in diabetic patients without periodontitis, 66 percent with mean 13 colonies of candida albicans were grew; whereas other two groups presented candida albicans in all samples and the highest mean of colonies was found in diabetic with chronic periodontitis and non-diabetic with chronic periodontitis, 80.5 and 37.8 respectively. The average number of colonies of candida albicans was Statistical difference between groups (p value <0.001). Conclusion: The result of this present study showed that accompaniment periodontitis and diabetes can doubled influence in increase average number of colonies of candida albicans in gingival crevicular fluid. [ABSTRACT FROM AUTHOR]

This article has endeavored to study in experimental survey, the effect of Central Bank Independence (CBI) on the output and inflation fluctuations in the Iranian economy, using vector Autoregressive (VAR) econometrics method. For this purpose, we started with the changes in output and inflation stability in bringing about good economic performance, over the period 1961-2014 years .The paper has introduced a new legal combined Central Bank Independence index, by the name of "Average (Mean) Index". According to the 40% amount of total on the base of this new index, it has been cleared that there was independence just during 1340- 1361 period. The results of Generalized Autoregressive Conditional Heteroskedasticity (GARCH) method indicated that the inflation and output variances trends were approximately inverse over this period, except in some short periods. The estimation of study model revealed the negative and significant of Central Bank Independence effect on output and inflation variances. It means an increase in Central Bank Independence will cause decreasing their fluctuations and will results more macroeconomic stability and better economic performance. According to the result of Variance Decomposition and analysis of Impulse- Response Functions, the positive impact of central bank independence on macroeconomic stability has been confirmed, but it was much more effective on the nominal sector and shrinking the inflation uncertainty than real sector and output instability. [ABSTRACT FROM AUTHOR]

Introduction: Dimensional stability of alginate impression materials is affected by several factors such as storage time, storage conditions and type of the impression material. This study was conducted to assess the effect of storage time on dimensional stability of two different alginates: Tropicalgin and Chromogel. Materials & Methods: In this experimental study, impressions were made of a master model with four metal cones on the occlusal surfaces of lower first premolars and third molars on both sides (teeth #1, #5, #12 and #16). The Impressions were divided into five groups in terms of the storage time in wet paper towels within a closed plastic bag before pouring the casts (15 min, 30 min, 60 min, 120 min and 24 h). For each group, 20 impressions and a total of 100 impressions were made. The impressions were poured with type III stone (Parsdental, Iran). Six dimensions (D1 to D6) between 4 cones were considered as the gold standard in order to compare with the same dimensions on the stone casts. Distances were measured by a digital caliper and data were statistically analyzed by MANOVA and one-sample t-test. Results: Dimensional changes increased over time for both alginates except for one sample (Tropicalgin at 30-min interval for D1, p value = 0.4). There were significant differences between the two materials at all the time intervals except for the first fifteen minutes. Dimensional changes were within the clinically acceptable limits (a change of 1.5% relative to the master model) up to 120 min for both alginates. Conclusion: The dimensional stability of Tropicalgin and Chromogel alginate impression materials was affected by storage time before pouring in stone and the material type. [ABSTRACT FROM AUTHOR]

MIL-101(Cr) stands as one of the extensively researched chromium-based metal-organic frameworks, comprised of chromium metal ions and terephthalic acid ligands. This study introduces an innovative approach to MIL-101(Cr) synthesis by employing ultrasound (UTS) irradiation. Our primary objective revolved around optimizing key operational parameters, namely time and temperature, using the central composite design method. Subsequently, we conducted an in-depth analysis using variance analysis to understand their respective impacts. To predict process behaviour, we developed quadratic equations under varying conditions, achieving a remarkable R2 value of 0.9998 to relate parameters and synthesis yield. Results revealed a more pronounced influence of time variation compared to temperature on the synthesis process. Moreover, we subjected the synthesized MIL-101(Cr) to rigorous characterization using FT-IR, XRD, SEM, TGA, and N2 physisorption techniques. Our findings showcased the synthesized MIL-101(Cr) possessing exceptional characteristics, including an ultra-high specific surface area (2143 m2. g-1), substantial pore size (0.8 cm3.g-1), and excellent thermal, chemical, and water stability. Further examination indicated the presence of microporous windows, mesoporous cages, and uniform octahedral particles ranging in size between 125-260 nm. Notably, our study emphasized the energy efficiency of UTS irradiation over conventional electric (CE) heating, highlighting its potential as a quicker, more efficient, and environmentally friendly alternative to conventional synthesis methods. [ABSTRACT FROM AUTHOR]

Background and Aims: To evaluate the effect of polishing on surface roughness of silorane-based composite using profilometery and Scanning Election Microscopy (SEM) and compare it with that of a methylmethacrylatebased composite and a glass ionomer. Materials and Methods: In this study, 3 groups (n=28) were tested: specimens of two composites (Filtek P90 and Filtek P60) and a glass ionomer (Fuji IX) which were prepared in polyethylene molds (4 mm diameter×10 mm height). Half of the specimens in each group were finished with 180-grit silicon carbide paper and the remaining were finished with 180-grit, and subsequently polished with 250, 400, 800, 1000, 2000, and 2500-grit silicon carbide papers. The surface roughness was evaluated using a contact profilometer and then mean (Ra) and maximum (Rmax) of surface roughness were recorded. Then, the surface of 4 specimens of each subgroup was observed under SEM. Statistical analysis was performed with T-test, ANOVA and Dunnett T3 tests. Results: In all materials, Ra was different between polishing with 180 and 2500-grit silicon carbide papers. In 180-grit group, only Ra of Filtek P60 and Fuji IX showed significant difference (P=0.01). In 2500-grit group, there was no significant difference between the Ra of Filtek P60 and Filtek P90 (P=0.56). Conclusion: Polishing is recommended for the glass ionomer and posterior composite restorations. [ABSTRACT FROM AUTHOR]

Introduction: IL-6 and IL-8 have an important role in orthodontic tooth movement and creation of periodontal diseases. Laser therapy in orthodontics has effect on decrease pain and increase regeneration of bone, acceleration of tooth movement and decrease inflammation in periodontoal tissues. The aim of this study, determination the effect of low laser therapy on GCF level of IL-6 and IL-8 during orthodontics treatments. Materials & Methods: In this clinical trial study, we chose 10 patients with crowding or protrusion, that they need fix orthodontic treatment with extract of two premolars in each side and then retract the anterior teeth. After complete SRP, the orthodontic treatments started. After clinical examination such as CAL, PD and BOP the teeth in one quadrant selected case groups and the other quadrant selected control groups. Low Level laser irradiation done in 0,2,7, 21 days and collection of GCF is done in 2,4,9, 23 days with paper cone in distal sulcus of canine for 30 second. Then all of the samples transferred to laboratory and then t-test ANOVA and LSD test done. Results: The average of changes in IL-6 and IL-8 in GCF at the 21 day after laser irradiation had a significant difference but in the other days we didn’t have a significant difference. Conclusion: Low level laser therapy at orthodontics treatment causes of decrease the inflammation and decrease the IL-6 and IL-8. [ABSTRACT FROM AUTHOR]

Introduction: Oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity, which is usually caused by the most common premalignant lesion of oral leukoplakia (OL). For changes of dysplasia and malignancy, the level of antioxidants in the blood and tissue of patients changes significantly, which may be effective in early diagnosis of malignancies. Therefore, the purpose of this study is to evaluate antioxidants (enzymatic and non-enzymatic) in the blood of patients with OSCC and OL. Material & Methods: This study is a case-control study and was conducted on 75 blood samples of patients with OSCC and OL referred to the Cancer Institute of Imam Khomeini Hospital, Ilam. Enzymatic antioxidants [catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GPx)] and non-enzymatic antioxidants (ascorbic acid, beta-carotene, vitamin E) were evaluated in the blood of patients. The data obtained from this study were evaluated by ANOVA test and the significance level (P<0.5) was considered. Results: The results showed that the mean age in the HC group was similar in both sexes, while in the OL group, the age of women was 4 years younger, and in the OSCC group, the age of women was 2 years older than men. CAT, as an antioxidant indicator, significantly increased in the OL group compared to the HC group and OSCC group (P < 0.000). Also, CAT and SOD activity in OSCC serum samples significantly decreased compared to the HC group (P < 0.000). GPx also showed a significant decrease in both OL and OSCC groups compared to the HC group (P < 0.000). The results related to the non-enzymatic antioxidant factors, beta-carotene, vitamin E, and ascorbic acid, significantly decreased in both OL and OSCC groups compared to the HC group (beta-carotene (P < 0.000), vitamin E (P < 0.000), and ascorbic acid (P < 0.000)). Discussion & Conclusion: The results of this study show that the level of enzymatic antioxidants and beta-carotene in is not related to the degree of dysplasia of oral leukoplakia, therefore, it is not possible to predict the probability of occurrence of malignant oral lesions based on the measurement of the level of antioxidants in patients with OL. [ABSTRACT FROM AUTHOR]

Introduction Elderly is a process that is genetically visible during the life of living things and decreases in the organism over time, which reduces the activities of the organs of the body. Although it is not an aging disease and most of the elderly can be seen in other age groups, the elderly process is facilitating physical diseases, including cancer. The formation of tumors becomes. These cells grow very rapidly and usually cause severe pain by pressing on healthy tissues and nerve fibers, blocking fluid flow in the body, and disrupting the activity of the organs. Method The present semi-experimental research design was used with a pre-testthen- test with the control group. The research community is all the 60 to 75- year-olds residing in Tehran in 2021 who have been diagnosed with Stage 1 and Stage 2 cancer, of which 30 elderly women were referred to medical centers for treatment. The semi-trial design was used to determine the effectiveness of the emotion therapy. The pre-test was first implemented and then accidentally performed in one of the two experimental groups of excitement treatment, and the control group received no training and was implemented at the end of the post-test training. Research Criteria: Over 60 years old, getting a cancer diagnosis, mental consciousness, lack of participation in another therapeutic program, wanting to cooperate, elderly with cancer, tendency to attend intervention, and exit criterion unwilling to participate in intervention. The selected sample was accessible through random selection into two groups of tests and certificates. The emotionbased treatment package was developed and presented in the format of 10 sessions, each 90 minutes long, and content validity was used to validate it. The research tool was the questionnaire on psychological adaptation to cancer by Watson et al. (1988). Coronbach's alpha was used for data analysis using conventional descriptive statistics (average and standard deviation) and inferential statistics (repeated measurement variance analysis). Results The results of the study showed that the emotional intervention package was able to significantly increase mental compatibility with cancer. In addition, the excitement intervention package was followed up after the posttest execution, and the results showed that there was no tangible post-test change after two months (p < 0.001). Discussion Therefore, excitement-based treatment with recovery experiences and changing the meaningful meanings of any experience has a corrective training for stabilized emotional strategies that enhance the use of efficient and positive strategies and better adaptation to the disease by breaking the inefficient strategy and better adaptation to the disease. Since this study was conducted on older women with cancer in Tehran, it is recommended that other cultural and gender groups be aware of the generalization of the results. [ABSTRACT FROM AUTHOR]

Citing national publications is considered as a qualitative measure for science localization in the current research. Consequently, the aim is to study this metric within the corpus of Iranian Scholar Journals in Social Science Domain between 2002 and 2010. The research uses citation analysis method. The references of six social science scholar journals were extracted from the papers and then divided into two groups of national and foreign publications. The studied journals were those which were regularly published in Iran between 2002 and 2010. The analysis was performed on a sample of 543 papers out of 1528 ones. The sampling method was based on the Cochran's function. An ANOVA test showed that the average number of citing to national publications is statistically unchanged in the journals' papers during the period mentioned above. On the other hand, the same average for foreign publications is growing. The correlation analysis determined that this growth follows a logarithmic function. The other finding concerns the differences between the average numbers of citing to the national publications in the studied journals. A one way ANOVA test revealed a difference between the journals from this point of view. Based on the Tukey's Range Test the results of ANOVA test is affected by the "Journal of Women Strategic Studies". It means, if this journal was omitted from the analysis, the rest five ones would statistically have the same rate of citing to the national publications. The citing rate to national publications ranges between 0.31 and 0.39 except for the journal mentioned above. Based on this metric, the tendency toward the use of national publications in the social science domain is constant despite the growing number of scientific productions in Iran. This means that the Iranian social science domain not only doesn't tend to localization of science, but its use of foreign science is growing in the span of time as well. [ABSTRACT FROM AUTHOR]

Background. Different shoe weights affect walking mechanics. Therefore, the purpose of this study was to determine the effect of sport shoe weight on lower extremity muscle activities in athletes with anterior cruciate ligament reconstruction during walking. It was hypothesized that reduced shoe weight results in decreased frequency content of selected muscles during walking. Methods. Twenty healthy males and athletes with ACL reconstruction volunteered and gave their written informed consent to participate in this study. Participants were male and physically active. Each participant performed three walking trials in each of the light (mass per shoe: 150 ± 18 g), medium (300 ± 18 g), and heavy (450 ± 18 g) conditions in a randomized order and electromyography were analyzed during walking. Results. EMG results showed that the increase in shoe weight was directly related to the increase in electrical activity of the muscles, but only in the swing phase was the electrical activity of the TA muscle decreased. Conclusion. Different shoe weights affect the electrical activity of the muscles and the walking speed. Therefore, lighter weight shoes are recommended for patients with ACL. Practical Implications. The results of this study show that light shoes are useful for patients with anterior cruciate ligament rupture and the use of lightweight shoes is recommended for people with anterior cruciate ligament rupture. [ABSTRACT FROM AUTHOR]

With the emerging of Internet, banks have gone through the traditional process and have reached the stage of modern banking in their career. Following this transition, banks became familiar with self-service technologies. Using self-service technologies has provided advantages such as speed and unlimited access to banking services. Despite these benefits, some people still use traditional banking. Many studies have examined the factors influencing the use of technology-based banking. These studies have examined such issues as the demographic characteristics of user/ none-user (such as gender, age, education level, perceived ease of use and usefulness). The purpose of this paper is to examine the behavior of users and non-users of self-service technologies in banking services. For that purpose seven types of behavior will be examined. To complete this research, 480 questionnaires was distributed between the customers of Parsian bank in Ahwaz; of which 397 questionnaires were collected. The research method is an applied research in terms of aim and in terms of method is descriptive. Analysis of variance (ANOVA) was used to test the hypotheses. The research results showed that five (word-of-mouth intention, repurchase intention, satisfaction, propensity to change banks and time sensitivity) between user and none-user is not same. But about other types of behaviors (price sensitivity and complaint behavior) the results do not show a significant differences. [ABSTRACT FROM AUTHOR]

Backgrounds and Objectives: Different studies have shown a relationship between social capital and health. The aim of this paper was to survey about the relation between social capital and health-related quality of life (QOL) among teachers. Materials and Methods: In this cross -sectional study, our target community was 375 people that were selected by Multi-stage cluster sampling method. For assessment of Social Capital Onyx and Bullen (2000) were used, and for assessing health-related QOL SF-36 questionnaires were used respectively. Data were analyzed with independent T, ANOVA, Pearson correlation and Regression tests. Results: The mean age of respondents was 40.7±5.26 and based on gender 51.9% of them were male. Mean and SD of total QOL and total social capital scores were 64.52±17.02 and 71.21±16.74 respectively. Pearson correlation test showed that there was a significant correlation between total social capital with total health-related QOL(r =0/153; p<0.004), cognitive social capital with physical health(r = 0/136; p<0.011) and also communicative social capital with mental health(r = 0/133; p<0.012). There was significant relationship between structural social capital and both dimensions of health-related QOL: physical health(r = 0/146, p=0.006) and mental health(r = 0/156, p=0.003). Also regression analysis showed that variables of "gender", "marital status" and "age" have not impact on the relationship between social capital and QOL and have been removed from model, but "income" was an effective variable in the main relationship of the research. Conclusion: Our finding showed that there was positive correlation between social capital and health- related QOL among teachers. It appears that focus voluntary groups activities could increases trust and personal network, and its issue could improve mental and physical health of teachers. [ABSTRACT FROM AUTHOR]

Introduction: We aimed to assess the outcomes of critical appraisal method beside lecturing versus lecturing method regarding theoretical sections among the student of msc of nutritional science. methods: This semi-experimental study was undertaken on 8 students of nutritional science in two semesters during 2009-2010. Some sections were taught via using critique of original articles, but others were taught using exclusive lecturing method. We assessed student's Knowledge by using a written examination, attitude via a 5 item-questionnaire and Skill via writing a review paper. SPSS software was used to analysis of data and student t test was used to compare the scores in two sections. Results: The mean of knowledge, attitude and skill grades in post-test were significantly higher in the critical appraisal sections (18.1±4.2 vs 15.9± 3.5; P=0.03, 4.0±3.5 vs 1.0±0.2; P=0.02 and 18.5±2.5 vs 15.0±3.5; P=0.04, respectively). Conclusion: teaching the theoretical sections beside criticizing of papers improves the knowledge, attitude and skill grades. [ABSTRACT FROM AUTHOR]

The walnut wood is one of the most important wood in Europe, Asia and Iran, which is used in various industries such as furniture, veneer, and construction due to its high resistance and texture. In this research, walnut trees from two different geographic locations, one from the forests in the north of Iran (Noor) and the other in the west of Iran (Shahrkord), were selected. The physical properties including dry density, basic density, shrinkage, and mechanical properties including bending strength, modulus of elasticity, compression parallel to the grain, shear, tensile parallel and perpendicular to the grain, tangential and radial screw withdrawal strength and toughness were measured using standard procedures as define in ISI3129 and ASTM D143-14. The moisture content of all samples during mechanical tests was 12%. The average dry density of Noor and Shahrekord walnuts was 0.61 and 0.57 (g/cm3 ) respectively. The results of variance analysis showed that the characteristics and physical properties of these two species were not significantly different except for dry density, radial, tangential and volumetric shrinkages. However, due to the higher density of Noor species, it showed higher mechanical strength compared to the Shahrekord species. [ABSTRACT FROM AUTHOR]

Introduction: Schizophrenia is a mental disorder in which the facts surrounding a person are interpreted as abnormal. The treatment aims to reduce symptoms and the possibility of disease recurrence. Aim: This study aimed to investigate the effectiveness of spironolactone on schizophrenia symptoms. Method: In this double-blind analytical and clinical study, 44 patients were randomly divided into two groups. The study was carried out in Quds Hospital and centers for psychiatric patients in Sanandaj city in 2019 and 2020. The number of patients decreased to 32 due to drug side effects and unwillingness to continue treatment. The instrument used was the scale test of positive and negative symptoms of schizophrenia. Datum were analyzed using chi-square and ANOVA with repeated measurements and independent t-tests by SPSS-23 software. Results: The results showed that out of 44 patients studied, 37 (84.1%) were men and 7 (15.9%) were women. The imbalance was due to the small sample size. There was no significant difference between the two groups in terms of sex distribution, literacy level, marital status, employment history, and background medication use (P>0.05). In addition, there was no significant difference between the two groups in terms of reducing negative symptoms (P=0.666), positive symptoms (P=0.748) and general symptoms (P=0.342). Conclusion: According to the finding, spironolactone has no significant effect on reducing negative, positive, and general symptoms. Therefore, it is suggested to carry out more studies using this drug (by removing the limitations of this study) and other drugs. [ABSTRACT FROM AUTHOR]

Introduction: Echinococcus granulosus is the causative agent of hydatid cysts, which are distributed worldwide. Nowadays, much research is being done to inactivate hydatid cyst protoscoleces. This study was conducted with the aim to compare the scolicidal effect of two chemical compounds 12 and 2 on hydatid cyst protoscoleces in vitro. Material & Methods: The scolicidal activity of two amini-hydrox-phenylcoumarin and amini-bromo-phenylcoumarin at concentrations of 1.2, 1.5, 1.10 and 1.100 after 15, 30 and 60 minutes of incubation was tested separately and each of the experiments was repeated three times. The viability of protoscoleces was checked with 0.1% eosin dye under a light microscope. Subsequently data were analyzed using GraphPad version 5 software and two-way repeated measures ANOVA and values (P > 0.05) was considered a significant level. Findings: The results of this study showed that the chemical compound aminibromophenylcoumarin at a concentration of 1.10 destroyed 100% of protoscoleces after 60 minutes of exposure compared to the control group, but amini-hydroxophenylcoumarin, at a concentration of 1.100 could destroy 98% of protoscolecia after 60 minutes of exposure. Discussion & Conclusion: The results of the present study showed that aminibromophenylcoumarin had stronger protoscolicidal effects than aminihydroxophenyl-coumarin. However, further studies and in vivo studies are needed to evaluate the efficacy of these chemical compounds. [ABSTRACT FROM AUTHOR]

Background and Aim Sexual function is an important part of menopausal women's lives, and changes in it, especially during menopause, can affect their health. The aim of this study was to compare the effectiveness of cognitive behavioral therapy (CBT) and acceptance and commitment therapy (ACT) on the sexual function of postmenopausal women. Methods & Materials This research was a quasi-experimental with pre-test, post-test and follow-up design with control group. The statistical population of the study included postmenopausal women who referred to Zanjan Health Center in 2020 to receive services. Among them, 45 were selected using the available sampling method and were randomly assigned to three groups of 15, and control group using randomly assigned block allocation method. Therapeutic sessions were held in 8 sessions and each session was held for 2 hours. Data were collected by FSFI (Female Sexual Function Index) and were analyzed using ANOVA with repeated measures analysis via SPSS software, version 24. Ethical Considerations This study was approved by the ethics committee of the Zanjan University of Medical Sciences (Code: IR.ZUMS.REC.1398.328). Results In the post-test and follow-up phase, there was a significant difference between both CBT and ACT methods compared to the control group in sexual function respectively (P<0.05, F=17.857), (P<0.05, F=12.115). That is, treatment with CBT and ACT improved the sexual function of postmenopausal women, which had a lasting effect for three months, and there was no significant difference between the groups involved in sexual function (P>0.05, F=0.494). Conclusion Cognitive-behavioral therapy and acceptance-based therapy have improved sexual function in postmenopausal women, so it is recommended that these therapies be used to improve the sexual function of postmenopausal women in health centers. [ABSTRACT FROM AUTHOR]

Background and Aim: Successful treatment of pulp disease largely depends on good prosthetics restoration after endodontic treatment. Therefore, the aim of this study was evaluated of knowledge and practice of Yazd general dentists about restoring endodontically treated teeth. Materials and Methods: In this descriptive cross-sectional study, the knowledge and practice of 150 general dentists in Yazd in relation to the restoration of endodontically treated teeth were studied by a valid and reliable questionnaire including demographic characteristics, 8 knowledge questions and 13 practice questions. Data were analyzed by SPSS17 software and t-test, ANOVA and Pearson correlation coefficient. Results: The dentists participating in the study were 54.7% female and 45.3% male with a mean. Their average score of knowledge was 11.08±2.89 out of 16 points. There was no statistically significant difference between the average score of knowledge in terms of gender, job experience and participation in related retraining (P-value >0.05). they preferred the cast posts and cores for the anterior (74 %) and posterior (74.7%) teeth. Most dentists used glass ionomer as a cement (92%) and normal saline as a root canal cleaner (72%). Conclusion: the average score of dentists' knowledge regarding the restoration of endodontically treated teeth was good. [ABSTRACT FROM AUTHOR]

Introduction: Somatic Symptom Disorder (SSD) is characterized by distressing somatic symptoms which are accompanied by disproportionate thoughts, feelings, and behaviors, has wide gender differences in prevalence, which has been less investigated in researches. Aim: The purpose of this study was to compare the physical (criteria A) and psychological symptom of SSD (criteria B) consist of cognitive, affective and behavioral in female and male patients. Method: This study was a descriptive and causal-comparative research. The participants included 60 Iranian women and 30 men with SSD in the age range of 18-60 years old who participated in the study based on the diagnosis of a psychiatrist by Convenience sampling method in 2021-2022. Data was collected by The Somatic Symptom Disorder-B (2017) Criteria Scale and The Somatic Symptom Scale8 (2014). For data analysis, MANOVA were applied by using SPSS-22. Results: The findings revealed that women with SSD generally showed more psychological symptoms compared to men and in the psychological subscales, affective (P=0.00) and behavioral (P=0.00) was more evident in them, however there was no significant difference between men and women in cognition of psychological subscales (P=0.18) and intensity of physical pain (P=0.13). Conclusion: According of the study, one of the factors of the difference in SSD prevalence can be from less expressing, not less suffering from the disorder in men. Studying the main causes of differences in the affective and behavior of psychological subscales such as cultural origin, can be effective in further studies. [ABSTRACT FROM AUTHOR]

Background & Aims: Diabetic cardiomyopathy (DCM) is a functional, metabolic, and morphological deterioration of the myocardium caused by changes in glucose homeostasis caused by diabetes. miRs play a significant role in the occurrence of DCM. Reducing the overexpression of miR373 gene has a potential role in the appearance of this disease. Therefore, the purpose of this research was to compare the effect of six weeks of aerobic and resistance training on the expression of miR373 gene in mice with diabetic cardiomyopathy and male Wistar rats. Methods: This research had a developmental goal, from the point of view of the experimental method and from the point of view of the laboratory execution method, with a post-test design. 36 healthy male Wistar rats with an average weight of 200 ± 20 grams and an age of 8 weeks were purchased from Pasteur Institute in Tehran. To induce diabetes, 50 mg/kg of streptozotocin (STZ) was injected intraperitoneally in a single dose to 27 rats. To confirm the validity of diabetes induction, glucose ≥ 200 mg/dl or hema index ≥ 3.5 were considered. According to research, diabetic cardiomyopathy occurs two months after the induction of diabetes. To confirm the occurrence of diabetic cardiomyopathy in the form of a pilot project, 3 heads of healthy rats (before the start of the research) and 3 heads of diabetic rats (after two months of becoming diabetic) were dissected and samples of myocardial tissue were taken. Rats with cardiomyopathy were randomly classified into four groups of 6 vertices (control, sham exercise, resistance exercise and aerobic exercise). A healthy group of 6 vertices was also considered for comparison with other groups. After two weeks of familiarization with the environment and learning to exercise, aerobic (running on a treadmill) and resistance (walking on an ascending ladder) training protocols were implemented for six weeks. 48 hours after the last training session (along with 12 hours of fasting), all rats were anesthetized using ketamine and xylazine and dissected and sampled from the left ventricular tissue. Real Time PCR was used to evaluate the expression of miR373 genes. For the statistical analysis of the data, ANOVA and T-correlated tests were used at the significance level of P ≤ 0.05. Results: Both exercise protocols led to a significant (P ≤ 0.05) decrease in fasting blood glucose (FBS) and insulin resistance index (HOMA-IR%). VO2peak (P: 0.1) of the aerobic group and 1RM (P: 0.73) of the resistance group increased significantly. The miR-373 gene expression level decreased in the control and sham diabetic groups compared to the healthy group, but increased in both exercise groups. But this increase was not significant (P > 0.05). It was also shown that resistance training had more significant changes on FBS and HOMA-IR indices compared to aerobic training (P = 0.001). Finally, aerobic and resistance training led to a significant increase in Vpeak (T = -4.9, P = 0.004) and 1RM (T = -7.68, P = 0.001). Conclusion: Aerobic and resistance training improved the aerobic capacity and strength of the training groups, respectively. In addition, both exercises led to the improvement of diabetic complications (increased the expression level of miR-373), but aerobic exercise caused a better improvement of diabetic cardiomyopathy complications. [ABSTRACT FROM AUTHOR]

Introduction: Covid-19 patients perceive a lot of stress and suffer from psychological symptoms including depression, stress and anxiety. Because these patients are required to comply with quarantine conditions, remote training can be used for these patients. Therefore, this study was conducted with the aim of investigating the effect of remote training of stress management in a cognitive-behavioral way on the psychological symptoms of covid-19 patients. Materials and Methods: In this randomized clinical trial, the research population was all the patients with Covid-19 referred to the Dr.Garazi hospital in Isfahan city in the winter of 1400. 70 people were selected by available sampling method and divided into two intervention and control groups (35 people) by limited randomization method. For the intervention group, remote training program on stress management was implemented in five sessions of 60 minutes in two weeks. The control group did not receive training. Psychological symptoms were measured before and after the training sessions using the DASS-21 questionnaire. The data were analyzed with SPSS21 software and at two levels of descriptive and inferential statistics and by performing chi-square tests, analysis of variance, independent and paired ttest, and analysis of covariance. Results: Remote training of stress management in a cognitive-behavioral way has had a significant effect on all dimensions of psychological symptoms of covid-19 patients in the intervention group and has reduced them in the intervention group. (p≤0.05). Conclusion: Based on the results, this method of training can improve the psychological symptoms of covid-19 patients. Considering the possibility of easy and comprehensive use of distance education, it is recommended to use this method of teaching patients in similar pandemic conditions. [ABSTRACT FROM AUTHOR]

Background & Aims: Diabetes mellitus is one of the most common chronic diseases in the world (1). Diabetes and hyperglycemia caused by diabetes lead to disorders in various organs such as lungs, heart, muscles, kidneys, etc. (9, 10). One of the main complications of diabetes is diabetic cardiomyopathy; Diabetic cardiomyopathy is the result of diabetes-induced changes in the structure and function of the heart. Diabetic cardiomyopathy occurs as a result of impaired glucose and lipid metabolism associated with diabetes, which leads to increased oxidative stress and activation of multiple inflammatory pathways that mediate cellular and extracellular damage, pathological remodeling of the heart, and diastolic and systolic dysfunction. Preclinical studies in animal models of diabetes have identified several intracellular pathways involved in the pathogenesis of diabetic cardiomyopathy and potential cardioprotective strategies for disease prevention and treatment, including anti-fibrotic agents, anti-inflammatory agents, and antioxidants (11). Cellular energy homeostasis is a fundamental process that governs the overall health of the cell and is critical for cell survival. Central to this is the control of ATP production and utilization, which is regulated by a myriad of enzymatic reactions controlling cellular metabolism (12). Adenosine monophosphateactivated protein kinase (AMPK) is an energy sensor with aberrant expression in various diseases, including diabetes (12). There is considerable evidence that AMPK is reduced in cardiac tissues of animals and humans with type 2 diabetes or metabolic syndrome compared with non-diabetic controls, and that AMPK stimulation (physiological or pharmacological) can ameliorate diabetesrelated cardiovascular complications (14). Considering the role of AMPK in energy metabolism in the heart, as well as the effects of diabetes and exercise on the gene and protein expression of this energy sensor, measuring the changes of this gene can improve our knowledge about the effect of different adaptations caused by different exercises, as well as the effect of lack of exercise. With the aim of investigating the effect of maintaining these adaptations after training (22, 23). However, so far, no research has been done that specifically compares the effect of two common training methods, continuous and intermittent training, followed by no training on cardiac AMPK gene expression in diabetic rats, which shows the necessity of the current research. According to the mentioned information, the present study was conducted with the aim of comparing the effect of a detraining period followed by aerobic and HIIT exercises on cardiac AMPK gene expression in alloxan-treated diabetic rats. Methods: In this experimental research, 48 male Wistar rats (age: 10-weeks; weigh: 220±20 grams) were randomly divided into six groups (n=8). One group was considered as a healthy control and the rest of the rats were made diabetic using a single dose of 90 mg/kg of alloxan. One group was considered as diabetic control; and the rats were divided into two groups of high-intensity interval training (HIIT) and continuous moderate aerobic training (MICT). After 12 weeks of training, half of the rats in each group were sacrificed; and the rats were sacrificed after 2 weeks of no training. MICT program was performed for 5 sessions per week with a gradual increase in speed (18-26 m/min) and time (10-55 minutes). HIIT program also included 5 30-minute sessions per week in the form of running on a treadmill with one-minute repetitions and 2-minute active rest between each interval. For statistical analysis, one-way analysis of variance and Tukey's post hoc test were used and the significance level (P ≤ 0.05) was considered. Results: The results showed that the induction of diabetes decreased the cardiac AMPK gene expression compared to the healthy control group (P < 0.001), also the results showed that after 12 weeks of training, there was a significant increase in the cardiac AMPK gene expression in the training groups compared to the control group. Diabetes control was observed (P < 0.001), but no significant difference was observed between the two exercise groups (P > 0.05). Also, the results showed that after 2 weeks of non-training, there was a slight decrease in cardiac AMPK gene expression compared to the training groups, and these changes were not significant (P > 0.05). Conclution: The results of the present study showed that induction of diabetes with alloxan decreased cardiac AMPK gene expression, which was related to hyperglycemia caused by induction of diabetes with alloxan injection. Previous research has also shown that a single dose of alloxan injection with 90 mg/kg body weight of rats induces diabetes (24-26). According to the findings of the present study, 12 weeks of continuous aerobic exercise and HIIT both significantly increased cardiac AMPK gene expression in diabetic rats, but no significant difference was observed between the two types of exercise. Based on the research conducted in animal models, exercise increases cardiac AMPK values, which are consistent with the results of the present study (30, 31). However, comparing the effects of continuous and HIIT exercises, the results of these two studies were different from our findings; In their research comparing the effect of moderate intensity continuous training and HIIT training on AMPK of skeletal and cardiac muscle, Wen et al. reported that the effects of HIIT training on increasing oxidative capacity and AMPK are more obvious (30); The results of Su et al.'s research showed better effects of continuous training on AMPK and PGC-1α gene expression in the HIIT group than continuous aerobic training (30). As shown in various animal models and patient studies, physical exercise is known to be cardioprotective and can partially compensate for cardiac damage. At the cellular level, exercise counteracts heart disease-related changes in these cellular pathways and can improve heart function (32). AMPK activation leads to the regulation of metabolism, protein transport, transcription factors and/or activators, kinases, and other enzymes and non-enzymatic proteins. AMPK increases substrate uptake and utilization in the heart, enhances mitochondrial biogenesis, and modulates the activity of specific proteins and transcription factors to exert cardioprotective functions (33). Therefore, exercise training can moderate the effects of diabetes on the heart by increasing cardiac AMPK. AMPK also plays an important role in reducing oxidative stress, regulating autophagy and anti-apoptosis of cardiomyocytes (29, 34). Exercise activates signaling molecules and transcriptional networks to promote physiological adaptations such as mitochondrial biogenesis (35). It has been reported that after swimming exercises in rats, the levels of activated AMPK showed a decrease in cardiac fibrosis due to the inhibition of NADPH oxidase (36). This finding has been confirmed as decreased AMPK activity by beta-adrenergic activation exacerbates cardiac fibrosis (37). These changes are important because exercise activates AMPK and thus may be able to inhibit pathological hypertrophy and cardiac fibrosis (38). Other findings of our research showed that 2 weeks of detraining after exercise decreased AMPK in both exercise groups, but this decrease was not statistically significant. In line with the findings of the current research, Cao et al also reported in their research that after the training period, a significant increase in AMPK level was observed, but after stopping training for 10 days, the AMPK level started to decrease, but the changes were not significant 40). Based on the results, it can be said that any two methods of continuous aerobic exercise and HIIT increase the expression of the AMPK gene; Also, after two weeks ofdetraining, cardiac AMPK gene expression is still high in diabetic rats. However, more research is needed to investigate the longer-term effects of non-exercise on AMPK gene expression and mechanisms related to non-exercise on diabetic cardiomyopathy. [ABSTRACT FROM AUTHOR]

Introduction: Despite the negative consequences of the Covid-19 pandemic on mental health, our knowledge of the changes in the severity of symptoms of psychological disorders during the pandemic is insufficient. Aim: The purpose of this study was to investigate the changes in the symptoms of anxiety, depression, obsessive-compulsive disorder, social anxiety, and generalized anxiety in the student population during the covid-19 pandemic. Method: This study is a longitudinal descriptive study in terms of data collection. A sample of 376 people was selected with the convenience sampling method from the Zanjan University of Medical Sciences and Zanjan National University undergraduate students using an online research platform (Porsal). The sample was evaluated in 4 stages at 6-month intervals from April 2020 to September 2021. BDI-II, BAI, GAD-7, OCI-R, and SPIN were used for data collection. The data were analyzed by repeated measure ANOVA using SPSS version 26, and R software. Results: During the Covid-19 pandemic, the intensity of symptoms of anxiety (p=0.008), obsessive-compulsive (p=0.023) and generalized anxiety (p=0.052) had an increasing trend, and with the subsidence of the pandemic conditions, the intensity of these symptoms has also been reduced. However, the intensity of depression was continuously increasing (p=0.001), and the intensity of social anxiety also had slight changes (p=0.964). Conclusion: Covid-19 pandemic has caused a significant increase in the severity of the symptoms of psychological disorders; therefore, it is necessary to investigate the underlying factors of these changes and other psychological consequences of the Covid-19 pandemic by conducting more extensive studies. [ABSTRACT FROM AUTHOR]

Background Mycophenolate mofetil as an immunosuppressive agent is widely administered in patients with kidney disorders and following organ transplantation. The amounts of xanthan gum and sorbitol, as two excipients of mycophenolate mofetil, are influential on the final quality and stability of the suspension. Objective In this experimental study, we aim to optimize the levels of xanthan gum and sorbitol in the Mycophenolate mofetil powder. Methods A Central composite design was used to prepare the formulations. The amounts of xanthan gum and sorbitol were considered as independent variables while the sedimentation volume (F value) and concentration of active pharmaceutical ingredient (API) after preparation and after 3 months of storage at 45 Cͦ were considered as dependent variables. The samples were prepared through wet granulation process. Chromatography analysis and determination of F value and API were then performed. Results Analysis of variance showed that the increase in the amounts of xanthan up to 75 mg provided higher F value and better protection of API after 3 months by 98%, while the increase of sorbitol from 10 to 25 g had no significant effect on these variables. Optimized sample composed of 16.69 g sorbitol and 68.81 mg xanthan gum. Predicted error was desirably less than 5%. Conclusion The proposed formulation of mycophenolate mofetil powder for oral suspension with optimum amounts of xanthan gum and sorbitol has good stability. High level of xanthan gum and moderate level of sorbitol are recommended for preparing an optimal product. [ABSTRACT FROM AUTHOR]

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Background and Aim: The type of circadian rhythms is essential in maintaining physical and mental health and recovery from the disease. This study aimed to investigate the role of circadian rhythms on sleep quality and corona anxiety in men and women. Methods & Materials: The present study is a descriptive comparative causal description. The statistical population included all 18-50 who participated in the survey online. People who completed the questionnaire online were selected for sampling. The research instruments included the circadian inventory rhythms Horne and Ostberg (1976), Petersburg Quality of Sleep Questionnaire (1989), and Alipour et al.’s (2020) Corona-related Anxiety Scale in the Iranian sample. Multivariate analysis of variance (MANOVA) and the Scheffe test were used to analyze the data. Ethical Considerations: This study was registered with the Ethics Committee Razi University Technology Units Development Center at Institute for Psychoanalytic Studies (No.: 99133). Results: The results showed that the mean of mental and corona physical anxiety in women and men with evening type is higher than in other classes. Men and women in the evening type have a lower sleep quality than in the morning and middle types. The results also showed significant differences between the types regarding corona anxiety, sleep quality, and sex. The difference between the mean of the morning type and evening types’ mean was more than other differences between the means. Conclusion: Individual differences in morning-evening types seem to play an essential role in the quality of sleep and the experience of corona anxiety [ABSTRACT FROM AUTHOR]

Background & Aims: Performing physical activity and having a healthy body is one of the most essential life needs of people with fatty liver. In recent years, studies have been performed on the relationship between fatty liver and arthrosclerosis. The results of these studies indicate the relationship between the Non-alcoholic fatty liver and arthrosclerosis of coronary artery disease. Non-alcoholic fatty liver disease is associated with a sedentary lifestyle and poor eating habits around the world Fatty liver is associated with an increased risk of cardiovascular disease and the formation of atherosclerotic plaques in the carotid arteries and coronary artery stenosis can affect extracellular matrix factors such as CTGF and RXFP1, which play a role in the formation or non-formation of fibrosis. Studies have shown that fatty liver disease can be effective in causing atherosclerotic changes in arteries and increasing the thickness of the carotid artery as an indicator of atherosclerosis, which can be seen even in mild degrees of fatty liver. Relaxin in all parts of the body can have different expressions of RXFP1 receptor in different arteries, so in rats this receptor is strongly expressed in aortic endothelial cells and RXFP1 activates cAMP, cGMP and cAMP signaling pathways in ERK1 / 2 endothelial cells On the other hand CTGF is mainly synthesized by liver cells in the liver and is strongly induced in liver fibrosis CTGF is induced by fibroblast TGF-β cells and mediates the growth and secretion of extracellular matrix. These results indicate that CTGF is the mediator of many TGF-β-probiotic activities Therefore, the aim is to investigate the effect of this disease on two extracellular matrix genes of the heart. Methods: In this experimental study, 24 male Wistar rats weighing 200-250 g were randomly divided into 3 groups: control, healthy and fatty liver steatosis. The control group was initially performed in the victim and tissue study And the two healthy and fatty liver groups spent two weeks in the same condition There was a healthy group from the beginning to the end of the study and they did not receive any intervention. Mice in the fatty liver group received oral tetracycline at a dose of 100 mg / kg at a dose of 1.5 ccs per mouse for two weeks. The average weight of the mice was 300 g, of which 100 mg / kg was used for 3 mice, of which 100 mg was dissolved in 4.5 cc and each rat was gavaged 1.5 cc. Fatty liver was modified by measuring liver enzymes (SGPT) and a number of biochemical variables. At the end of the second week, rats two groups were healthy and fatty liver48 hours after the last day (10 to 12 hours of fasting), the studied rats in each group were anesthetized by intraperitoneal injection of a mixture of 10% ketamine at a dose of 50 mg/kg and 2% xylosin at a dose of 10 mg/kg. became were sacrificed and heart tissue sample were taken to test for RXFP1 and CTGF gene expression. In each group, tissue analysis was performed by Real Time PCR technique. First, primer design was performed and then total RNA was extracted from tissues and converted to cDNA. Then cDNA was Replicated by PCR and examined for the expression of the mentioned genes. Results: After the second week and examining expression level of RXFP1 and CTGF genes between control, healthy and fatty liver groups, ANOVA test results showed that the expression level ofRXFP1 and CTGF genes (p = 0.0001 and p = 0.0001, respectively) In the fatty liver group, significantly increased compared to the healthy and control groups Considering the value of P<0.05, the null hypothesis that there is no significant difference between the level of RXFP1 in different research groups was rejected with 95% confidence. The results between the steatosis group and the other two groups were significant in increasing the level of RXFP1 gene expression. Therefore, it can be said that in the presence of fatty liver, the expression of RXFP1 gene increases in the heart tissue of male rats in order to inhibit fibrosis. Also, in terms of significance, the results between the steatosis group and the other two groups were significant in increasing the level of CTGF gene expression. Therefore, it can be said that in the presence of fatty liver in the steatosis model, the CTGF gene expression increases in line with the increase in cardiac fibrosis. Overall, our results showed that with the onset of fatty liver disease, both connective tissue growth factors and relaxin increased in the heart, and an increase in connective tissue growth factor indicates cardiac tissue damage, which can lead to heart tissue fibrosis. Therefore, these findings can help new therapies aimed at modulating the effects of CTGF and the use of RXFP1 as a new direction for further clinical studies. Our other findings showed that with induction of fatty liver, the level of RXFP1 in heart tissue increased from the beginning and did not change until the end of the two weeks. The expression level of RXFP1 gene in steatosis fatty liver groups (BS, CS) was significantly higher than the other 2 groups on the other hand the increase in connective tissue growth factor (CTGF) in this study was probably to produce extracellular matrix and compensate for their degradation, and the increase in RXFP1 was to prevent collagen deposition in ECM connective tissue growth factor (CTGF) in cardiac tissue increased sharply, such that its rate increased up to 7 times in the first two weeks compared to the control group, and this increase continued until the end of the two weeks, that increased 10 times However, this method should be considered with more caution because high expression of CTGF increases the level of fibronectin, collagen I and III proteins in the extracellular matrix, followed by myocardial infarction Conclusion: The fatty liver model of steatosis increases the expression of cardiac CTGF gene and fibrosis, and also increases the RXFP1 gene, which has anti-fibrosis activity. CTGF (CCN2) in response to tissue damage initiates signaling pathways of connective tissue regeneration Therefore, and cardiac tissue fibrosis. RXFP1, which is a component of the extracellular matrix and is most commonly expressed in aortic endothelial cells exerts most of its physiological effect on the cardiovascular system through NO (Nitric oxide). [ABSTRACT FROM AUTHOR]

Introduction: Primary stress can impair the nervous structure including the hippocampus and behavioral functions such as memory; therefore, paying attention to neutralizing the destructive effects of stress on the body has been one of the debatable topics among researchers. Considering the role of physical activity in reducing stress in previous studies, this study aimed to investigate the effect of four weeks of swimming training on learning and spatial memory in neonatal rats separated from their mother. Material & Methods: In this study, 40 male albino Wistar rats were randomly divided into four groups (separation from mother, separation from mother and swimming training, swimming training, and control). The method of separating the infants from the mothers was used to make stressful conditions. Rats from separation groups were separated from mothers 6 h per day starting from the day after birth for one month. For physical activity, swimming training was performed for four weeks (five sessions per week) incrementally to measure stress and blood glucose level in mice, and the Morris Water Maze test was used to assess the learning and spatial memory. (Ethic code: IR.UT.SPORT.REC.1399.009) Findings: The results of the analysis of variance test showed that the blood glucose in the group of rats that were separated from their mothers was significantly higher, compared to the control group (P=0.045), indicating that stress was successfully induced in these rats. Moreover, the results of the multivariate analysis of the variance test showed that although stress had no significant impact on spatial learning, the results of the exploration test showed a significant decrease in the percentage of entering the target quadrant (P=0.05) and the time spent in the target quadrant in the group separated from mother (P=0.029), compared to the control group. Therefore, spatial memory was degraded due to stress in the group of rats that were separated from their mother, compared to the other groups. However, swimming training in the group of rats that was separated from the mother could neutralize the destructive effects of stress on spatial memory and the percentage of entering the target quadrant (P=0.02) as well as the time spent in the target quadrant (P=0.05). Discussion & Conclusion: The results showed that although stress did not have a negative impact on spatial learning, it had a destructive impact on memory. On the other hand, swimming training as a treatment method could largely neutralize the negative effects of stress and improve memory. [ABSTRACT FROM AUTHOR]

This paper compares real and accrual (accounting) earnings management and the level of conservatism in successful and unsuccessful firms of Tehran Stock Exchange. In addition to unbalanced Panel data regression analysis, t-tests and two-way analysis of variance are utilized to test the research hypothesis. Using a sample of failed and continuing firms during the period from 1997 to 2009, it is found that prior to failure; failed firms achieve manipulation through both discretionary accruals manipulation and by implementing real operating actions. In addition, companies with low probability of bankruptcy have successfully managed earnings compared to firms with high probability of bankruptcy. Finally, finding indicates the existence of non-conservative approach in both the successful and unsuccessful firms. [ABSTRACT FROM AUTHOR]

Background and Objective: Nanosilver particles are one of the functional nanotechnology filed. These nanoparticles have antibacterial characteritics. Combination therapy is one of new and specific therapeutic regiment in medicine. Eucalyptus plant is useful in growth inhibition of bacteria. This study was done to evaluate the inhibitory effect of alcoholic eucalyptus extract with nanosilver on E.coli growth. Materials and Methods: In this laboratory study, E.coli was cultured in nutrient agar medium. Primarily 50 ml of bacteria was inocolulated in each plate, antibiograms disc contiminated with 3.1, 6.25, 12.5, 25 and 50 ppm concentration of nanosilver accompanied with 100% of etanolic extract of eucalyptus were placed in each plate subsequently. Diameter of inhibitory zone were evaluated following 24, 48, 72 hrs in 6th and 8th days. Data were analyzed using SPSS-15, ANOVA and Tukey tests. Results: After six days, inhibitory growth zone diameter of E.coli was 0.5 mm. This diameter in experimental group with 3.1, 6.25, 12.5, 25 and 50 ppm of nanosilver in combination with etanolic extract of eucalyptus were 0.55, 0.58, 0.82, 0.83 and 1.02 mm. Inhibitory growth zone in group of 12.5, 25 and 50 ppm of nanosilver was significant in compared to the control (P<0.05). Conclusion: The most proper time of inhibitory effect on E.coli growth is six day after treatment in combination of 50 ppm nanosilver particles with extract of eucalyptus. [ABSTRACT FROM AUTHOR]

Background and Aim: As composite-dentin bond strength is affected by cavity preparation and the bond strength of composite resin to new and used bur prepared dentin has not yet been evaluated, this study evaluated the effects of cutting dentin with different cutting efficacy (new and used) of burs on composite-dentin shear bond strength using self-etching primer bonding system and total etching bonding system. Materials and Methods: Sixty caries free human 3rd molar were sectioned in occlosal surface to expose dentin, then polished with silicon carbide paper and randomly divided into four groups. Each group was prepared in a depth of 0.5mm of dentin, using new diamond bur, or used diamond bur. To change into a used bur, each new rough diamond bur had to work on bovine enamel for 30 minutes, under a load of 150g. Then, each group was bonded, using a total etch adhesive (single Bond) or a self etch adhesive (clearfil SE Bond) So there were 4 groups : 1-SE Bond, New bur; 2-SE Bond , used bur; 3-Single Bond , New bur ; 4-Single Bond, used bur. Similar composite capsules(Filtek Z250) were bonded to dentin surface and cured, specimens were stored in physiologic saline for 48h at 37° c , then put under shearing load to define composite - dentin shear bond strength. Results were interpreted via statistical analysis (T-test & two - way variance). Results: Shear bond strength of each group was as follows: l-(27.3Mpa), 2-(33.5Mpa), 3-(16.9Mpa) 4- (19.3Mpa). Statistical analysis proved that shear bond strength of used diamond bur prepared groups (2,4) was more than new diamond bur prepared ones (1,3). This statistical difference, specially, was seen between SE Bond groups (1,2) but not between single Bond groups (3,4). Also, shear bond strength of (SE Bond) bonded groups (1,2) were more significantly than (single Bond) bonded ones (3,4). Conclusion: This study show that Bur cutting efficiency influences composite - dentin shear bond strength especially when the adhesive is SE Bond (used bur> new bur) Also type of adhesive affects on composite - dentin shear bond strength. (SE Bond > Single Bond). [ABSTRACT FROM AUTHOR]

Background Marital infidelity is a crisis for couples and families. identifying an effective treatment approach at the lowest cost can be effective in preventing and intervening in injuries caused by infidelity. Objective The aim of this study was to compare the effectiveness of emotion-based couple therapy and self-compassion-based therapy on emotion regulation in women affected by infidelity. Methods This quasi-experimental study was designed as pre-test-post-test with follow-up. The study population included all couples involved in marital infidelity who referred to Iranmehr Counseling and Psychological Services Center in Rasht, Iran in 2020, from which 20 couples were selected as the sample by available sampling method. Granfsky emotion regulation questionnaire was used to collect data and emotion-focused couple therapy sessions and self-compassion-based therapy were performed for 16 sessions of 4 hours (one treatment every two hours) on a weekly basis. After three months of treatment sessions, couples also participated in a follow-up session in order to measure the duration of treatment. Data were analyzed using combined analysis of variance. Results The results showed that both therapies are effective in increasing the emotional regulation of couples, but there is no significant difference between emotion-oriented couples therapy and compassion- based therapy on emotion regulation (F = 1.57 and P = 0.218). Conclusion Both treatment approaches in counseling centers were very effective in helping incompatible couples to improve and reduce marital problems, increasing satisfaction, especially in couples affected by infidelity. [ABSTRACT FROM AUTHOR]

Introduction: Attention Deficit Hyperactivity Disorder is a childhood disorder that is associated with a persistent pattern of symptoms of inattention, hyperactivity or inappropriate impulsivity, which usually continues into adulthood. Aim: The purpose of this study was to investigate the impact of the video game Minecraft on the Cognitive flexibility of ADHD athletes students. Method: The study was a quasi-experimental study with a pre, post and follow-up design with a control group. The statistical population of the study was 79 ADHD athletes students from 9 to 16 years old in 2020 in Lorestan province. Of these, 30 students were randomly selected and divided into two groups control and experimental. Subjects were evaluated three times (pretest, posttest, follow up) with Wisconsin Card Sorting Test. Also, to test the hypothesis, multivariate analysis of covariance, repeated measures analysis of variance, Bonferroni test and Spss 26 software at the significance level of 0.05 were used. Results: The results of cognitive flexibility scores showed a significant difference between the two groups in the three stages of measurement (P=0.0001). Bonferroni showed a significant difference between groups in the components of cognitive flexibility, the number of categories (P=0.027) and preservation error (P=0.0001). That is, Minecraft improved Cognitive flexibility in the experimental group, but no change was observed in the cognitive flexibility of the control group. Conclusion: It can be concluded that Minecraft improves the cognitive flexibility of ADHD athletes student. [ABSTRACT FROM AUTHOR]

Background: The aim of this study was to compare the effectiveness of "cognitive-behavioral therapy" (CBT) and "emotion-focused therapy" (EFT) on quality of life (QOL) in patients with irritable bowel syndrome. Materials and Methods: Consenting irritable bowel syndrome patients referring to a specialized clinic for gastroenterology in Tehran, Iran (Masoud Clinic) were enrolled in a randomized, controlled study using pre-test, post-test and follow-up assessments. The participants were randomly allocated to one of the three treatment groups: the first group received eight weeks of weekly CBT, the second group received eight weeks of weekly EFT, and the third group received their usual care without any specialized psychological intervention (control). The measurement tool of this study was the specific QOL test for patients with IBS (IBS-QOL). Twofactor analysis of variance with repeated measures (mixed analysis of variance), and one-way covariance analysis were used for analysis as appropriated. Results: We found that CBT and EFT both had a significant effect on improving QOL in the post-test and follow-up phase, but CBT was not effective on the component of sexual concerns with respect to the QOL of patients with IBS. Conclusion: Therefore, CBT and EFT affect the quality of life of patients with IBS, but CBT did not affect the sexual anxiety component of QOL in these patients. EFT was a more appropriate approach and has a long-lasting effect. [ABSTRACT FROM AUTHOR]

Introduction: One of the most common childhood disorders considered by psychologists and psychiatrists is Attention Deficit/Hyperactivity Disorder, which leads to attention deficit, hyperactivity and impulsivity in affected people. Aim: The purpose of this study was to investigate the impact of Chess training in students with ADHD. Method: The statistical community of the present quasi-experimental study was 76 students with ADHD in Khorramabad city in the academic year of 2019-2020. 32 students were selected by convenience sampling and randomly divided into two groups of 16 controls and experiments based on age, sex and pre-test results. And the experimental group received chess training for 11 consecutive weeks and a weekly session of 60 to 90 minutes. Subjects were evaluated three times (pre-test, post-test, two-week follow-up) with Connors and Swanson questionnaires and data were analyzed by ANOVA and Bonferroni test and Spss 21 software. Results: The results of the study showed a direct and high correlation between the results obtained from both Swanson and Connors measuring instruments and the positive effect of chess training on students with ADHD. (P=0.001, F=20.17). Conclusions: Due to the positive effect of Chess training on the symptoms of ADHD, it is suggested that Chess training be used to reduce the symptoms of ADHD. [ABSTRACT FROM AUTHOR]

Background and Aim Several microRNAs are involved in regulating muscle mass, which plays an essential role in hypertrophy and atrophy of skeletal muscle, The present study examined the expression of some genes as regulators of muscular atrophy following a period of inertia in rats. Methods & Materials For this purpose, 18 male Sprague-Dawley rats were divided into three groups (Control, Exercise+inactivity, and Inactivity). The exercise+inactivity group run on the treadmill for 18 weeks and five times per week. The hindlimb of the animal was immobilized for seven days with the casting method. Soleus muscle was extracted and the expression of the genes was measured by the RT-PCR method. Univariate ANOVA and Tukey post hoc test was used to determine the differences (α=0.05). Ethical Considerations The Ethics Committee of the Tehran University of Medical Sciences Research approved this study (Code: IR.SUMS.REC.1396.S 463). Results Results showed that immobilization in both Exercise+ inactivity and inactivity groups, compare to the control group, increased expression of miR-1 genes (P<0.10), FOXO3a (P<0.001) and decreased expression of miR-206 (P<0.007) and IGF-1 (P<0.001). This difference was statistically significant. Conclusion According to the results of this study, it can be said that changes in the expression of RNAs by chromatography cause changes in the expression of muscle regulating genes, and although endurance exercises have protective effects, they cannot prevent these changes. [ABSTRACT FROM AUTHOR]

Background and Aim Alzheimer's Disease (AD) is a neurodegenerative brain disease that gradually destroys memory and cognitive skills. The disease is caused by the formation of beta-amyloid plaques, oxidative stress, dysfunctions in the cholinergic system, neuronal killing inflammation, and ultimately brain atrophy. Donepezil and hyoscyamoside have inhibitory effects on these pathogens; therefore, their impact on the learning process of Alzheimer’s rats in the Morris Water Maze was investigated. Methods & Materials In the present experimental study, 60 male rats of Wistar breed with approximately 7 weeks age within the control group (rats that received normal water and food), the PBS group (underwent surgery), PBS group (received solvent Aβ), the first Alzheimer›s group (animals that received betaamyloid by Alzheimer’s surgery, second Alzheimer’s group (after Alzheimer’s surgery, they received 1 cc of normal saline daily, and treatment groups that treated the rats with beta-amyloid after Alzheimer. In the hyoscyamoside group, they received 10 mg/kg daily of hyoscyamoside for 28 days. The donepezil group received it 4 mg/kg daily for 28 days by gavage. The Morris Water Maze test was used to evaluate learning and memory. Data were analyzed by ANOVA statistical analysis and Post Hoc test. Ethical Considerations The Ethics Committee in Biomedical Research, Islamic Azad University, Science and Research Branch approved the research (Code: IR.IAU.SRB.REC 1397.057) Results Beta-amyloid injection caused extensive damage to memory. The treatment groups with hyoscyamoside and donepezil spent less time and distance with a significant level (P<0.001) than the group of Alzheimer’s patients to find the hidden platform. In the reminder phase, where the previously hidden platform was located, they spent more time, with a significant level (P<0.001) in the local quarter. Conclusion Treatment of rats with hyoscyamoside and donepezil improved spatial memory in Alzheimer’s rats. They appear to play a significant role in the prevention and treatment of Alzheimer’s disease. [ABSTRACT FROM AUTHOR]

Background and Aim Parental acceptance is an important parameter in selecting the proper behavior management technique during pediatric dental treatment. The present study aimed to compare the effects of different informing methods on acceptance of parents about behavior management techniques used in pediatric dentistry. Methods & Materials This quasi-experimental study was conducted on one 162 parents of 3-7-year-old uncooperative children who were candidates for dental treatment. They were randomly divided into three groups. Their acceptance about six behavior management techniques including general anesthesia, voice control, hand-over-mouth, parental separation, active and passive physical restraint were assessed by a questionnaire. After determining the level of acceptance, the information about the techniques was presented through three ways include writing, verbal and visual methods. Finally, their acceptance of each technique and the reasons for non-acceptance were re-evaluated. Data were analyzed in SPSS v.23 software using ANOVA and t-test. Ethical Considerations This study obtained its ethical approval from the Research Ethics Committee of Arak University of Medical Sciences under code: IR.ARAKMU.REC.1398.102. Results The informing methods significantly increased the parents’ acceptance about behavior management techniques. According to the ANOVA results, the effect of visual presentation method in general anesthesia technique was significantly lower than that of other methods (P<0.05), while its effect in active physical restraint technique was significantly greater than that of other methods (P<0.05). There was no statistically significant difference between the effects of informing methods in other behavior management techniques. Conclusion Informing parents about pediatric behavior management techniques increase their acceptance. Informing by visual presentation is the most effective method for increasing their acceptance of physical restraint technique, while in their acceptance of general anesthesia technique other informing methods are more effective. [ABSTRACT FROM AUTHOR]

Background and Aim Non-alcoholic fatty liver disease is a type of accumulation of fat in the liver cells. Moreover, portulaca oleracea has hypolipidemic properties. Accordingly, the present study aimed to investigate the effect of a combination of training and portulaca oleracea supplementation on plasma lipid profile and liver ultrasound in obese women with nonalcoholic fatty liver. Methods & Materials The study population consisted of 40 to 60-year-old obese women with non-alcoholic fatty liver disease. In total, 40 obese women with nonalcoholic fatty liver disease were randomly selected and divided into 4 groups. The study groups included training (n=10), training + supplementation (n=10), placebo (n=10) and supplementation (n=10). Before and after the intervention, sonography of the liver and blood tests were performed. The Paired Samples t-test and Analysis of Variance (ANOVA) were used to analyze the obtained data. The significance level was set at P<0.05. Ethical Considerations This study was approved by the Research Ethics Committee of Islamic Azad University, Rasht Branch, Iran (code: IR. IAU.RASHT.REC. 1397. 034). Moreover, it was registered at the Iranian Registry of Clinical Trials (IRCT) (code: IRCT201903090429871). Results The obtained data suggested that 12 weeks of portulaca oleracea supplementation and combination training significantly decreased the plasma concentrations of cholesterol (P=0.001), triglyceride (P=0.00), LDL (P=0.00), and significantly increased serum HDL levels (P=0.00) in the exercise + supplement, supplement, and exercise groups (P<0.05). Liver ultrasound data also improved in the exercise + supplement (P=0.02), and exercise (P=0.00) groups. Conclusion Portulaca oleracea supplementation with combination exercises could be effective in reducing plasma lipids and improving liver ultrasound in obese women with nonalcoholic fatty liver. [ABSTRACT FROM AUTHOR]

Background and Aim Physical complaints that have no clear cause are a process that is commonly seen in patients with Somatic Symptom Disorder (SSD). The increasing number of patients with this disorder and its related chronic symptoms including changes in quality of life and loss of individual efficiency has created social and psychological economic costs for these patients and their families. Methods & Materials This descriptive cross-sectional study conducted on 70 patients with SSD having digestive symptoms and chronic pain referred to the health centers in Semnan, Iran in winter 2018. They were selected using a convenience sampling method. The data collection tools were 15-item Patient Health Questionnaire Physical Symptoms (PHQ-15) and Rorschach test (Exner’s Comprehensive System). In order to analyze the collected data, multiple linear regression analysis, logistic regression analysis, and multivariate ANOVA were performed in SPSS V. 22 software. Ethical Considerations The present study was approved by the Research Ethics Committee of Semnan University of Medical Sciences (Code: IR.SEMUMS.REC.1397.029). Results Perceived location indices including D and Dd scores in Rorschach test were able to significantly differentiate the SSD patients from controls (P<0.05). In the logistic regression model, 70% of participants were classified properly. Conclusion There is difference in projective responses between SSD patients and controls, and patients were less holistic. Anxiety and psychiatric symptoms were also higher in patients with SSD. [ABSTRACT FROM AUTHOR]

Background and Aim There is a high correlation between depression and anxiety in children which are also related to laterality. This study aimed to compare generalized anxiety and social anxiety in sinistral and dextral children with depression symptoms. Methods & Materials This is a study with a causal-comparative design. The study population consisted of all primary students (fourth to sixth grade) of Arak Province in Iran. A convenience sampling method was used to select study samples. Prior to study, following questionnaires were completed: Children's Depression Inventory, Brief Scale of Generalized Anxiety Disorder, and Liebowitz Social Anxiety Scale for Children and Adolescents. Then, those with depression score of 19 and higher were assigned into two groups of sinistral (n=31) and dextral (n=35), and compared in terms of generalized anxiety and social anxiety. Ethical Considerations This study obtained its ethical approval form the Research Ethics Committee of Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1397.298). Results The results of multivariate analysis of variance showed a significant difference in two study variables between groups (P=0.001). Moreover, based on the results of univariate analysis of variance, sinistral children had higher generalized anxiety compared to dextral children; however, they were not significantly different in terms of social anxiety. Conclusion Considering the higher vulnerability of depressed sinistral children to anxiety disorders, they are more likely to need specific ways of preventing and treating depression and generalized anxiety disorder. [ABSTRACT FROM AUTHOR]

Background and Aim Multiple Sclerosis (MS) is an unpredictable disease that can change individuals' lifestyle. The purpose of this study was to investigate the effect of a Mindfulness-Based Stress Reduction (MBSR) program on functional disability of patients with MS. Methods & Materials The is an experimental study with pre-test/post-test/follow up design using control group. The study population consisted of all male and female patients with MS living in Neyshabur county, Iran. Of these, 47 were selected using a convenience sampling technique and randomly assigned into two groups of intervention (n=22) and control (n=25). The intervention group received MBSR therapy for 8 sessions, while the control group received no intervention. The follow-up was performed after one month. Subjects’ functional disability was measured by using the World Health Organization Disability Assessment questionnaire. The collected data were analyzed using SPSS v.21 software usingrepeated measurements Analysis of Variance (ANOVA). Ethical Considerations This study obtained its ethical approval from the Research Ethics Committee of Neyshabur University of Medical Sciences (code: IR. NUMS.REC.1397.004) Results The results of univariate ANOVA showed the significant effect of time and the interaction effect of time and group on functional disability of samples. The results of between-group ANOVA a significant difference between the intervention and control groups in functional disability (p <0.05). Pairwise comparison of the interaction effect of time and group showed a significant difference between the pre-test, post-test and follow-up scores (P = 0.001), but no significant difference was reported between the posttest and follow-up scores. Conclusion The MBSR program could reduce the functional disability in patients with MS due to ease of treatment, faster patient education, and the short duration of intervention sessions.. [ABSTRACT FROM AUTHOR]

Background: The aim of this study was to develop a therapeutic plan based on hypnotherapy for patients with irritable bowel syndrome (IBS) and determine the effectiveness of this treatment on the intensity of IBS symptoms and rumination of patients with IBS. Materials and Methods: The research design was a quasi-experimental with a pre-test, a post-test, and 3 months of follow-up. Of the patients who were referred to gastroenterology clinics in Tehran, 32 patients with IBS were randomly divided into two groups; hypnotherapy group and control group. Medical treatment along with hypnotherapy was individually conducted for eight sessions in the intervention group and the control group received only medical treatment. IBS Symptom Severity Scale (IBS-SSS) and rumination were completed in pretest, post-test, and follow-up stages by the patients and data were analyzed with repeated measures analysis of variance. Results: The variable scores of symptoms severity and rumination in experimental group was significantly lower than the control group (p < 0.05) and the effect of the therapeutic plan persisted until the follow-up stage. Conclusion: The results showed that hypnotherapy can be an effective treatment for patients with irritable bowel syndrome. Therefore, psychological treatment is essential for the management of these patients. [ABSTRACT FROM AUTHOR]

Background: Gastroesophageal reflux disease (GERD) is a common disorder, which is associated with mental disorders. Therefore, it is essential to study mental health and strategies for coping with stress, in such individuals. This study was performed to compare Profile of Mental Health and Strategies for Coping with Stress in Women with and without Gastroesophageal Reflux Disease. Materials and Methods: The design of this study was descriptive-causal comparative. The population included all women with and without Gastroesophageal Reflux Disease, from Zahedan province in year 2018. 46 women who were detected as having GERD and were advised to receive gluten-free products from the relevant centers and gastrointestinal clinic were selected and 47 healthy individual who were matched with respect to demographic characteristics with the patients with GERD were selected by purposive sampling method. The participants answered SCL-90-R and Andler & Parker coping strategies questionnaires. Results: The results of multivariate analysis of variance showed that the mean scores of somatic symptoms (F = 17.41), interpersonal sensitivity (F = 3.8), depression (F = 10.59), anxiety (F = 16.68), phobia (F = 4/97), psychosis (F = 4/34), and avoidance style (F = 20/20) were significantly more in patients with GERD compared with healthy people. Conclusion: Mental health in patients with GERD is significantly worse than healthy people and the use of avoidant coping strategies in such patients is more common than healthy individuals. Therefore, it is essential to pay attention to the psychological status of such patients. [ABSTRACT FROM AUTHOR]

Introduction: Hope has a significant role in coping with chronic diseases, such as diabetes mellitus. It seems that the improvement of psychological capital in patients with diabetes is one of the strategies for health promotion in these patients.The aim of this study was to determine the effectiveness of hope-based therapy in psychological capital among patients with type II diabetes mellitus. Materials and Methods: This semi-experimental research was carried out on 40 patients with diabetes referring to the healthcare centers affiliated to Sirjan University of Medical Sciences, Sirjan, Iran, and Health Services in 2018-2019, using a pretest-posttest design. The study population was selected through purposive sampling technique, and then randomly assigned to intervention and control groups. The intervention group received eight 90-minute sessions of hope therapy. The intervention was based on the theory of hope proposed by Senyder, Herth, and Ruston and a selection of Molana poems focusing on hope and positivism issues. The data were collected in three stages namely, before, immediately after, and 3 months after the intervention, using the psychological capital Questionnaire developed by Luthans et al. data analysis was performed in SPSS software (version 22) using repeated measures ANOVA at a significance level of 0.05. Result: The results showed significant differences between the two groups in terms of the psychological capital and its components (P<0.05). In addition, the effect of intervention was stable in the intervention group. Conclusion: Hope therapy led to the improvement of psychological capital and its components (i.e., hope, resilience, optimism, and self-efficacy). Therefore, it is essential to consider hope therapy interventions when planning for the improvement of psychological capital in patients with diabetes. [ABSTRACT FROM AUTHOR]

Friction stir welding is a solid state process which is developed by Twi institute in 1991. In this paper, lap welding of 5456 aluminum alloy sheets were carried out while hard working H321 sheet with a thickness of 5 mm was on top of a 2.5 mm thickness annealed sheet and the simultaneous effect of rotation speed of tool, feed rate and tool angle parameters on failure force and the height of hook in friction stir welding were investigated using response surface method. After evaluation and analysis of welding samples, response surface method was used using experimental results and several verification models were performed for error estimation. The results of mechanical properties of model show 3.88 percent average error with experimental results. In proceeding, the analysis of variance was used for investigation of the welding parameters effect on welding mode variations and it was seen that feed rate has the greatest effect on failure force and rotation speed has the greatest effect on the hook height and tool angle has the lowest effect in comparison with this two parameters.