1. [Association between the use of blood components and the five-year mortality after liver transplant].
- Author
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de Morais BS, Sanches MD, Ribeiro DD, Lima AS, de Abreu Ferrari TC, Duarte MM, and Cançado GH
- Subjects
- Adolescent, Adult, Aged, Female, Humans, Male, Middle Aged, Retrospective Studies, Time Factors, Young Adult, Blood Component Transfusion, Liver Transplantation mortality
- Abstract
Background and Objectives: Liver transplant (LT) surgery is associated with significant bleeding in 20% of cases, and several authors have demonstrated the risks related to blood components. The objective of the present study was to evaluate the impact of using blood components during hospitalization in five-year survival of patients undergoing LT., Methods: One hundred and thirteen patients were evaluated retrospectively. Several variables, including the use of blood components intraoperatively and throughout hospitalization, were categorized and evaluated by univariate analysis using Fisher's test. A level of significance of 5% was adopted. Results with p < 0.2 underwent multivariate analysis using multinomial logistic regression., Results: Parenchymal diseases, preoperative renal dysfunction, and longer stay in hospital and ICU are associated with greater five-year mortality after LT (p < 0.05). Unlike the intraoperative use of blood components, the accumulated transfusion of packed red blood cell, frozen fresh plasma, and platelets during the entire hospitalization was associated with greater five-year mortality after liver transplantation (p < 0.01)., Conclusions: This study emphasizes the relationship between the use of blood components during hospitalization and increased mortality in five years after LT., (2011 Elsevier Editora Ltda. All rights reserved.)
- Published
- 2011
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