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OBJECTIVE Investigation of the levels of anxiety and depression among individuals addicted to substances who requested help from a Mental Health Rehabilitation Program. METHOD To conduct this study quantitative methodology was considered appropriate. The study sample consisted of 79 individuals addicted to substances, who completed an anonymous, self-administered questionnaire recording the sociodemographic data and Spielberger's Anxiety Scale and Beck's Depression Scale. RESULTS Inductive analysis revealed statistically significant variations in stress and depression of the subjects in relation to gender, age, family situation and in particular the stage of treatment. CONCLUSIONS It is apparent that a Mental Health Rehabilitation Program for addicts should meet the demands of substance-dependent individuals for treatment of both anxiety and depression. [ABSTRACT FROM AUTHOR]