1. [Peptic Ulcer Disease Associated with Helicobacter pylori Infection].
- Author
-
Yeo SH and Yang CH
- Subjects
- Anti-Bacterial Agents therapeutic use, Bacterial Proteins metabolism, Bacterial Proteins toxicity, Helicobacter Infections complications, Helicobacter Infections drug therapy, Helicobacter Infections microbiology, Helicobacter pylori metabolism, Peptic Ulcer etiology, Proton Pump Inhibitors therapeutic use, Helicobacter Infections diagnosis, Helicobacter pylori pathogenicity, Peptic Ulcer diagnosis
- Abstract
Although the global prevalence of peptic ulcer disease (PUD) is decreasing, PUD is still one of the most common upper gastrointestinal diseases in the world due to Helicobacter pylori infection and increased use of non-steroidal anti-inflammatory drugs. In Korea, the prevalence of H. pylori infection is also declining, but it is still the major cause of PUD. The outcomes of H. pylori infection are caused by imbalances between bacterial virulence factors, host factors, and environmental influences. In this review, we describe the prevalence trends of H. pylori infection in Korea, the mechanism of H. pylori infection-related PUD, and treatment strategies.
- Published
- 2016
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