1. [Correlates of Cognitive Impairment of Rheumatic Disease: Systematic Review and Meta-analysis].
- Author
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Mo J, Park J, and Oh H
- Subjects
- Anxiety, Cognition, Cognition Disorders complications, Databases, Factual, Depression complications, Humans, Hypertension complications, Obesity complications, Rheumatic Diseases complications, Risk Factors, Cognition Disorders pathology, Rheumatic Diseases pathology
- Abstract
Purpose: This study was conducted to synthesis the results of research on relationships of cognitive impairment with multi-dimensional correlates of rheumatic disease through a systematic literature review and meta-analysis., Methods: For the study purpose, 23 studies were selected through a systematic process of searching the literature., Results: The study results showed that among general characteristics, age and education were the variables having a significant relationship with cognitive impairment. Among health risk factors, obesity appeared to have a significant positive relationship with cognitive impairment. For past history, diabetes and hypertension were shown to have a significant positive relationship with cognitive impairment. It was noted also that aPL, one of the physiological factor, had significant association with cognitive impairment. None of the medication related factors had a significant relationship with cognitive impairment. Results showed that among disease related factors, disease activity had the highest relationship with cognitive impairment. Depression, among psychological factors, was the only variable having a significant relationship with cognitive impairment., Conclusion: The findings indicate that the variables strongly impacting on cognitive impairment in rheumatic disease are depression and disease activity.
- Published
- 2016
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