1. Risk of mortality and cause of death according to kidney function parameters: a nationwide observational study in Korea
- Author
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Sehyun Jung, Soojin Lee, Yaerim Kim, Semin Cho, Hyuk Huh, Yong Chul Kim, Seung Seok Han, Hajeong Lee, Jung Pyo Lee, Kwon Wook Joo, Chun Soo Lim, Yon Su Kim, Dong Ki Kim, Kyungdo Han, and Sehoon Park
- Subjects
albuminuria ,epidemiology ,glomerular filtration rate ,glomerular hyperfiltration ,kidney function test ,Internal medicine ,RC31-1245 ,Specialties of internal medicine ,RC581-951 - Abstract
Background Further study is warranted to determine the association between estimated glomerular filtration rate (eGFR) or albuminuria and the risk of death from diverse causes. Methods We screened >10 million general health screening examinees who received health examinations conducted in 2009 using the claims database of Korea. After the exclusion of those previously diagnosed with renal failure and those with missing data, 9,917,838 individuals with available baseline kidney function measurements were included. The primary outcome was mortality and cause-specific death between 2009 and 2019 identified through death certificates based on the diagnostic codes of International Classification of Diseases, 10th revision. Multivariable Cox regression analysis adjusted for various clinicodemographic and social characteristics was used to assess mortality risk. Results The hazard ratio of death was significantly high in both the eGFR
- Published
- 2024
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