Search

Background: In its short history, reproductive medicine has achieved many fertility-related milestones, including: the arrival of in vitro fertilization in the late 1970s, the development of intracytoplasmic sperm injection in the early 1990s, the first ovarian transplant a decade ago, and the first livebirth after uterine transplantation in 2014. This paper provides a brief overview of the indications and methods, as well as future perspectives, available for fertility preservation. Current Concepts: More women are undergoing fertility preservation for medical or social reasons. Fertility preservation aids cancer patients in retaining the ability to procreate. Despite the high survival rate of malignancies in young patients, chemotherapy and whole abdominal irradiation have cytotoxic effects on reproductive organs. Cancer treatments can significantly reduce a patient's reproductive capacity and thus result in irreversible infertility. Early ovarian failure is also a common by-product of additional cancer treatment, bone marrow transplantation, or autologous transplantation. The current options for fertility preservation in cancer patients include cryopreservation (of embryos, oocytes, and ovarian tissue) and gonadotropic-releasing hormone agonist treatment (before and during chemotherapy). Fertility preservation is a means for female cancer patients to preserve their fertility and delay childbearing. Fertility preservation can also aid women who wish to delay childbearing for personal reasons. Since the indications for fertility preservation are different for each patient, individualized treatment strategies should be employed depending on the patient's situation. Discussion and Conclusion: Health professionals must inform women who are undergoing cancer treatments or purposefully delaying childbearing about the risks of decreased fertility. Appropriate fertility preservation options must be provided for these female patients. [ABSTRACT FROM AUTHOR]

Purpose: The purpose of this paper (a literature review study) was to confirm the trend of nursing research for head and neck cancer patients in Korea. Methods: Research databases were reviewed and analyzed from 13 papers (2004 through 2019 using KISS, NDSL, RISS, DBpia, and the National Assembly Library. As a result of this paper, we found that there were many studies that used questionnaires. Results: Measurement variables related to head and neck cancer patients were physical variables related to oral condition, psychological variables related to depression and anxiety, social support, family support related to family, and quality of life as a result variable. Conclusion: Therefore, integrated nursing intervention strategies and clinical nursing research considering the physical, psychological, social, and family aspects of head and neck cancer patients are needed. Based on the results of this study, we propose qualitative research on head and neck cancer patients, development of educational programs, intervention studies to verify effects, and development of clinical practice guidelines. [ABSTRACT FROM AUTHOR]

Purpose: In this study, the hospice nursing research trend in 1998~2017 was investigated by analyzing research articles on hospice nursing. Methods: Literature search was performed with keywords of 'nursing' and 'hospice on an academic research information service. Also reviewed were all articles published in the Korean Journal of Nursing Science and its 8 subcategory journals, the Korean Journal of Hospice and Palliative Care and the Korean Hospice Association from 1998 through 2017, except thesis papers. Results: In 2013~2017, 79 articles (31.0%) were relevant, up over 7% from 61 articles (23.9%) in 2008~2012. The most studied field was psychology (92 papers, 36.2%) in the Korean Journal of Hospice and Palliative Care. Enrolled in most papers were patients with end-stage cancer (75, 29.5%), which is overwhelmingly high. Most studies used quantitative methods (183, 72.0%). Recognition was the most studied theme (62, 24.4%), and 16 of them focused on recognition of death (6.3%). Intervention studies totaled 34 (13.4%), and most of them (7, 2.8%) were conducted for palliative education. Conclusion: Most hospice nursing studies were quantitative studies, conducted with patients, and hospice nursing intervention programs were similar to each other. Thus, more studies with hospice patients and their families are needed. And more experimental and qualitative studies are needed to build an evidence-based nursing study environment. Considering how most studies examined psychological factors, physiological factors such as pain, a major issue in hospice care, should be analyzed in experimental studies to construct a pain intervention program for hospice patients. [ABSTRACT FROM AUTHOR]

Purpose Cancer is a disease affecting millions of people and one of the primary causes of death worldwide like cardiovascular diseases. Nonpharmacological and nonoperative methods such as proper exercise-intervention, nutrition, maintaining the activity of daily living (ADL), psychological methods can also improve the physical function, cancer progression, and health-related quality of life (HRQOL). However it is extremely important, little light shed on the impacts of exercise-intervention on cancer prevention and treatments. Therefore, the purpose of this study was to analyze the impacts of nonpharmaceutical approaches such as diverse exercise-intervention on cancer prevention and treatments with psychological and physiological health for cancer patients. Moreover, this paper wants to combine knowledge regarding the many experimental papers and systemic reviews of cancer researches and exercise intervention liter-ature. Methods A meta-analysis and systemic reviews of the impacts of an exercise intervention on cancer prevention and treatments were conducted to the PRISMA guidelines. 20 research articles were selected for final inclusion and extraction. And electronic analysis such as PubMed, Google scholar was carried for this study up to May 2020. The search keyword was ‘exercise-intervention and cancer’. Results We can suggest that physical exercise-intervention might be a suitable combination partner to exercise-related immune therapy in the prevention, delay, and treatment of cancer patients. Moreover, physical exercise-intervention directly enhances the QOL, ADL, healthy life, and even resilience of cancer patients. Conclusions Therefore, these exercise interventions can be effective at reducing cancer symptoms, and enhancing cancer treatments for diverse and many cancer patients. Reversing low muscle mass can enhance cancer therapy outcomes and mortality. Nutrition strategies also might be helpful. A Follow-up study about specific high-quality tailoring exercise-intervention program on counteracting cancer symptoms, cancer prevention and treatment, physiological and psychological health and HRQOL is urgently needed in this area.

Purpose: The purpose of this study was to analyze the research trends of nursing researches done on cancer patients' nutrition in Korea and to make suggestions for future studies. Methods: A total of 100 studies from 1989 to 2015 were analyzed. 22 nursing studies were selected for analysis the based on keywords ‘nutrition', ‘cancer' and ‘patients'. Results: Of 100 papers, 27 were doctoral dissertation and master's theses, 73 were from academic journals, 3 were thesis studies, and 19 were reported research in academic journal in nursing fields. Quantitative researches accounted for 92.0% while 20% among them were nursing researches, and other types of studies were 2%. The most frequently used research type was non-experimental 65.0%, while the ratio of experimental researches was 27.0%. The most frequently used research subjects were cancer patients without diagnostic classification with 37.0%. The most common issue of qualitative studies was the patient's nutrition condition. Conclusion: The further studies about cancer patients' nutrition condition need to be done with various approaches such as concept or tool development study, multi-disciplinary research, qualitative study and education program development study. [ABSTRACT FROM AUTHOR]

Purpose: This study was conducted to understand the unmet needs and quality of life of colorectal cancer survivors immediately after the end of primary treatment and 5 years later. Methods: This study was designed as a cross-sectional, descriptive, and correlation study. Data collection was conducted from July 2021 to December 2021. A total of 256 colorectal cancer survivors participated in the study, including 121 immediately after treatment and 135 five years later, among survivors of colorectal cancer who visited colorectal surgery outpatient clinics at two hospitals in Korea. We investigated unmet needs and quality of life immediately after the end of treatment and after five years. Data were assessed by using self-reported structured questionnaires. Results: It was confirmed that colorectal cancer survivors had higher unmet needs and lower quality of life immediately after the end of treatment than after 5 years. Additionally, regardless of the period after the end of treatment, the higher the unmet needs, the lower the quality of life. Conclusion: Based on the results of this study, when developing and applying nursing interventions for managing colorectal cancer survivors, it will be helpful to improve the quality of life by identifying differences in unmet needs for each survival period. [ABSTRACT FROM AUTHOR]

Purpose: This study aimed to examine the effect of pain, anxiety, depression, perception dignity, and spiritual well-being on hospice patients' attitudes toward dignified death. Methods: A total of 130 terminal cancer patients admitted to hospice · palliative care institutions in Korea participated in the study. Data were collected using self-report questionnaires and analyzed using descriptive statistics, an independent t-test, one-way ANOVA, Pearson's correlation coefficient, and hierarchical multiple regression using SPSS Statistics 26.0. The assessment tools were the Brief Pain Inventory, Hospital Anxiety and Depression Scale, Perception of Dignity Scale, Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being Scale, and Attitudes toward Dignified Death Scale. Results: The mean scores were as follows: 5.25 for pain, 11.98 for anxiety, 14.56 for depression, 22.12 for spiritual well-being, 14.38 for perception of dignity, and 93.12 for attitudes toward dignified death. The results of the hierarchical multiple analysis revealed that spiritual well-being (β=.36, p<.001) was predictive of the attitudes toward dignified death (R²=.13, p<.001). Conclusion: Spiritual well-being is associated with hospice patients' attitudes toward dignified death. The results highlight the necessity to develop effective nursing intervention programs that promote spiritual well-being for hospice patients' attitudes toward dignified death. [ABSTRACT FROM AUTHOR]

Purpose: The purpose of this study was to identify the changes of chemotherapy induced peripheral neuropathy (CIPN), sleep quality, and quality of life and their interrelationships following chemotherapy. Methods: A sample of 52 patients who had been diagnosed with stomach cancer receiving oxaliplatin containing chemotherapy were included in a prospective longitudinal study. The assessment tools were Chemotherapy-induced Peripheral Neuropathy 20, Pittsburgh Sleep Quality Index, and EORTC Quality of Life- Cancer. The data were collected at three time points: pre-chemotherapy, post-chemotherapy, and three months after the completion of chemotherapy, using questionnaires given between June 2017 and March 2019. Data were analyzed using descriptive statistics, repeated measures analysis of variance, and multiple regression analysis. Results: Post-chemotherapy, 19.2% of patients complained of CIPN and 21.2% exhibited CIPN at three-month follow-up. Repeated measures ANOVA showed a significant increase in CIPN after chemotherapy and it remained high at three-month follow-up (F = 39.90, p< .001). Functional quality of life (F = 8.23, p< .001) and symptom quality of life (F = 7.88, p= .001) also showed significant decreases after chemotherapy, and symptom quality of life remained low at three-month follow-up. However, for sleep quality, no significant main effect of time point was shown. CIPN and sleep quality were a factor influencing quality of life with an explanatory power of 48.3% at post-chemotherapy and 65.3% at three-month follow up. Conclusion: These results suggest that chemotherapy is highly associated with CIPN and symptoms affecting quality of life in cancer patients. Nursing intervention is needed to monitor and relieve these symptoms of patients during the cancer care trajectory. [ABSTRACT FROM AUTHOR]

Purpose: The purpose of this study was to identify the knowledge structure of Asian Oncology Nursing (AON) from 2002 to 2018. Methods: Abstracts from 382 studies were reviewed and analyzed using the text network analysis program, NetMiner 4.3. Keywords network trends were compared before and after 2012 when the journal title changed from Journal of Korean Oncology Nursing to Journal of Asian Oncology Nursing. Results: 'Cancer,' 'patient,' 'quality of life,' 'breast,' 'nurse,' 'depression,' 'health,' 'nursing,' 'pain,' 'family' were the top 10 most frequent keywords, and 'cancer,' 'patient,' 'quality of life,' 'health,' 'nursing,' 'family,' 'intervention,' 'effect,' 'hospital,' and 'therapy' were the dominant keywords that ranked highest in co-appearance frequency. Core keywords changed before and after 2012. After 2012, depression, health, symptom and pain were the keywords ranked that replaced nursing, education, family, and intervention from before 2012. Four subtopic groups were identified: 1) cancer treatment, education and information, 2) chemotherapy and psychological adjustment, 3) psychosocial adjustment of cancer survivors, and 4) process of cancer intervention and support. Conclusion: This study provides a general overview of research trends of the Asian Oncology Nursing Society. Findings of this study may guide future research directions in Asian Oncology Nursing research. [ABSTRACT FROM AUTHOR]

Purpose: The purpose of this study was to test the effect of visual information blocking nursing intervention (VIBNI) on stress and anxiety of patients undergo chemoport insertion in operating rooms. Methods: A non-equivalent control quasi-experimental design was used. Forth eight participants were enrolled and randomized to experimental group (VIBNI group, n=24) and control group (n=24). All participants received chemoport insertion under local anesthesia. During chemoport insertion, participants allocated to the VIBNI group had their both eyes covered with gamma-sterilized white gauze (5cm x 20cm, 0.5cm in thickness and 4g in weight) that can transmit light of 330Lux. Data from 43 participants were analysed after excluding 5 participants who withdrew (3 in the VIBNI group, and 2 in the control group) due to hypertension and anxiety history. Blood pressure and pulse were measured for stress. Blood sample (3 mL) was obtained before and during the procedure to measure serum cortisol level. State anxiety and VAS was measured for anxiety. Results: The difference of cortisol level between two groups was statistically significant after VIBNI intervention (p=.007). In terms of systolic blood pressure (p=.005) and pulse (p<.001), interaction of two groups appeared to be significant over time. Conclusion: In our sample, participants received the VIBNI reported lower stress responses (cortisol level, systolic blood pressure and pulse) during chemoport insertion. Based upon our preliminary results, further evaluation in a larger sample and objective anxiety is warranted. [ABSTRACT FROM AUTHOR]

Purpose: This study was designed to explore positive and negative aspects of the caregiver reaction and identify factors influencing psychological well-being among family caregivers of home-based cancer patients. Methods: The participants were 139 family caregivers from two cities. These caregivers took care of he family member in the home. Data were collected utilizing the Caregiver Reaction Assessment Scale and the Psychological Well-being Scale. Results: Self-esteem was the highest reaction reported among the family caregivers. There were significant correlations between caregiver reaction and their psychological well-being. In multiple regression analysis, self-esteem and family support were predictors of psychological well-being among family caregivers (F=13.71, p<.001, Adj. R2 =.393). Conclusion: The results demonstrated that self-esteem and family support impacts the psychological well-being among cancer family caregivers. Thus, nursing intervention are needed to enhance self-esteem to improve psychological well-being among family caregivers. [ABSTRACT FROM AUTHOR]