1. 原子間力顕微鏡：多細胞系の力学物性計測の現状.
- Author
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岡嶋孝治
- Subjects
- *
CELLULAR mechanics , *ATOMIC force microscopy , *NANOINDENTATION , *MONOMOLECULAR films , *EMBRYOS - Abstract
Atomic force microscopy (AFM) provides a less invasive approach to characterize mechanical properties of single cells and multicellular systems without any treatment. A variety of AFM nanoindentation techniques has been developed allowing to quantify the mechanical properties of cells and to explore the spatial and/or temporal dynamics of single cell stiffness in multicellular systems such as cell monolayer and developing embryo. This commentary addresses the reliability and limitations of the present AFM to obtain the universal and specific features of cell mechanical properties in multicellular systems. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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