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Kawasaki disease (KD) was considered to be good prognosis in self-limited at first. But, sudden death followed KD has been reported. It became clear that KD produce the peculiar state of myocardial infarction in infants and young children. Now, KD took the place of the rheumatic fever and got the most important disease of acquired heart disease in childhood. Cardiovascular disorder is mainly included with the coronary arterial aneurysm. And aneurysm in an subaxial and iliac artery were complicated. Every organ flame in a whole body was produced with systematic vasculitis mainly on a medium size or small size artery of a whole body. We summarize about complications of a cardiovascular system and the other organs followed KD.

Based on the nationwide database of Japan in January 2006, a cumulative number of the patients exceeded 200,000, while 90,000 patients are now older than 20 years old. The Japan Kawasaki Disease Committee established the guideline of its management in 2002. In adult patients with coronary sequelae, there is no doubt on the necessity of life-long-follow-up, while there is still arguments on how do we care the adult patients with no or mild coronary involvements in the acute phase which regressed spontaneously. The coronary artery sequelae of Kawasaki disease may be an important cause of ischemic heart disease in young adults, particularly under 40 years of age. In this review, we discuss how we care adult patients with a history of Kawasaki disease with coronary sequelae. Finally, we recommend opening the outpatient office for adult patients with a history of Kawasaki disease, because the frequency where adult patients followed Kawasaki disease stops consulting a medical institution became high.