1. [COMPLETE RESECTION OF URACHAL CARCINOMA WITH SIGMOID COLON INVASION AFTER FOLFOX CHEMOTHERAPY: A CASE REPORT].
- Author
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Ito A, Takata R, Matsuo T, Kimura T, Otsuka K, Ishii S, Tokiwa S, Tanji S, Sugimura J, Omori S, and Obara W
- Subjects
- Adenocarcinoma diagnostic imaging, Antineoplastic Combined Chemotherapy Protocols administration & dosage, Colectomy methods, Colon, Sigmoid diagnostic imaging, Combined Modality Therapy, Cystectomy methods, Fluorouracil administration & dosage, Humans, Leucovorin administration & dosage, Male, Middle Aged, Neoplasm Invasiveness, Organoplatinum Compounds administration & dosage, Sigmoid Neoplasms diagnostic imaging, Tomography, X-Ray Computed, Treatment Outcome, Urinary Bladder Neoplasms diagnostic imaging, Adenocarcinoma pathology, Adenocarcinoma therapy, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Colon, Sigmoid pathology, Colon, Sigmoid surgery, Sigmoid Neoplasms pathology, Sigmoid Neoplasms therapy, Urinary Bladder Neoplasms pathology, Urinary Bladder Neoplasms therapy
- Abstract
A 45-years-old man presented discharge of abscess from the umbilicus with lower abdominal pain. CT scan showed huge tumor from the bladder to the umbilical part with sigmoid colon invasion. He was diagnosed as urachal carcinoma, which was confirmed by pathological examination. We started FOLFOX chemotherapy according to advanced colon cancer. Approximately 80% of reduction was accomplished after 11 courses of FOLFOX. We performed radical cystectomy with sigmoid colon resection. Pathological examination revealed complete resection with negative surgical margin. No recurrence and metastasis were observed after 30 months of surgery. Urachal carcinoma is often advanced cancer when diagnosed. Effective chemotherapy is not established well. FOLFOX chemotherapy demonstrated the well antitumor effect in this case.
- Published
- 2018
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