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Your search keyword '"Diphenhydramine analysis"' showing total 2 results
Start Over Descriptor "Diphenhydramine analysis" Language japanese
2 results on '"Diphenhydramine analysis"'

1. [Current topics and problems in toxicology laboratories--7: Occurrence of poisoning due to 15 chemicals and introduction of analytical methods for diphenhydramine and SSRIs].

Subjects
Acetaminophen poisoning, Benzodiazepines poisoning, Humans, Japan epidemiology, Organophosphate Poisoning, Chromatography, High Pressure Liquid methods, Diphenhydramine analysis, Gas Chromatography-Mass Spectrometry methods, Histamine H1 Antagonists analysis, Hypnotics and Sedatives analysis, Poisoning epidemiology
Published
2010

2. [Two cases of diphenhydramine related suicide].

Author

Yonemitsu K, Koreeda A, Kohmatsu H, Ohtsu Y, Mimasaka S, and Tsunenari S

Subjects
Adult, Diphenhydramine adverse effects, Diphenhydramine analysis, Female, Gas Chromatography-Mass Spectrometry, Gastrointestinal Contents chemistry, Humans, Hypnotics and Sedatives adverse effects, Hypnotics and Sedatives analysis, Male, Middle Aged, Carbon Monoxide Poisoning, Diphenhydramine poisoning, Forensic Medicine, Hypnotics and Sedatives poisoning, Suicide
Abstract

Two suicidal cases associated with ingestion of diphenhydramine (DPH) were reported. Case 1 is a typical DPH overdose case of a young man with the blood DPH concentration of 12.2 microg/ mL. Case 2 is a double suicide of a man and a woman. They ingested DPH and fell asleep in a vehicle which had a cooking clay charcoal stove. Their blood DPH concentrations were 0.4 and 0.7 microg/mL, which were high enough to make them sleep. Their cause of death, however, was carbon monoxide poisoning with blood CO-Hb concentration of 14 and 19%. DPH is a low toxic agent and is available as an OTC drug in Japan. Similar fatal cases can be expected to happen in Japan.

Published
2007

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