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第一章：変温動物, 我々が普段目にする氷は無数の単結晶氷の融合物，即ち多結晶氷である．単結晶氷は規則的に配列した水分子でできているが，これと同じ規則性をもつ水分子が不凍タンパク質（Antifreeze Protein，AFP）の分子表面にも存在することが最近の研究から分かって来た．即ち，AFPは小さな氷結晶を表面にまとったタンパク質と言うことができる．この様な物質が水中に存在するとき，その水を0℃以下に冷やすとどのようなことが起こるのだろうか？AFPは生物にどのような能力を付与しているのだろうか？本稿では，特に魚類由来AFPの構造と機能に関する著者らの研究を紹介する．, A general block of ice is composed of an infinite number of single ice crystals, which is called ice polycrystalline state. Antifreeze protein (AFP) is a macromolecule that locates regularly organized hydration waters on its surface, whose arrangement is also adopted in a single ice crystal. As the consequence, AFP can specifically bind to single ice crystals, which prevents the ice polycrystalline state formation. We have been performed exploration of AFP against various cold-adapted organisms since the late 1990s, and found that many edible fishes available in the general Japanese food markets contain AFP in their body fluid. This finding enabled us to develop a mass-preparation technique of fish-derived AFPs, for which we have been performed structural and functional analyses and technological applications for many years. The advanced knowledge obtained from our results may ultimately realize a new AFP-technology that may prevent water freezing though the binding to single ice crystals, which may keep alive cells, tissues, and animals in the supercooled environment. The present review describes the overview of the waterfreezing mechanism and our research findings on the fish AFPs including their structure, function, and applicability for both industry and medical fields.

In recent years, internships (hereinafter abbreviated as IS) have been attracting attention.At Institute of Technologists, a 40-day long-term IS is conducted.According to the report on student satisfaction in basic internships compiled by the Institute of Technologists, about 98% of students show a high level of satisfaction with IS, However,effects of IS student’s employment choices and awareness of working in society are still room for consideration.Therefore, in this study, we conducted a follow-up survey on IS for all students belonging to the construction department of Institute of Technologists from 2018 to 2019.From the results of the survey, current long-tarm IS gained high satisfaction from students but it is guessed that many students have not been utilizing their experiences enough.From the above, assisting students is important to reduce problem such as miss-match. For that reason, it is necessary to conduct IS which is easy students to image awareness of working in society clearly.In addition, conducting this survey over time, it can be index that makes students and company understand each other., 本研究では，本学の建設学科に属する全学生を対象とし，2018 年度から2019 年度にかけてIS に関する追跡調査を実施した．調査結果からIS の評価および職業選択への影響度を経年比較によって検証し，就業観の形成に与える影響を分析する．

The purpose of this study is to evaluate the training time and the accuracy of the work quantitatively, focusing on the training of Grade 3 of National Trade Skill Test & Certification(NTSTC) for the skill education of young people. Based on the results, we will make a basic study on the ideal guidance and optimization of education that young technicians require to acquire skills., 本研究で取り上げる国家技能検定は労働者の技能と地位の向上を図ることを目的に，昭和44 年から厚生労働省主導のもと中央職業能力開発協会が全国的に同一基準の試験(実技および学科)を実施し，一定の基準を満たしている者を国家技能士と認めている．国家技能士には令和2 年6 月現在130職種があり，職種によって特・1・2・3 級，単一等級および外国人技能実習生向けとして基礎級が定められている．本研究で取り上げている国家技能検定3 級とび職種とび技能士(以降とび3 級と略) ⁴⁾は“初級の技能者が通常有すべき技能及びこれに関する知識の程度”と職業能力開発促進法で定義されている．専門高校でも技能教育の一環として，国家技能検定3 級の取得を目標に指導する例があるが指導者の定性的な評価で指導を行っている傾向が少なからず見受けられる⁵⁾⁻⁶⁾．

Due to recent changes in social conditions related to employment, efforts to support good matching between students and companies have become important in university education. The 40-day internship at Institute of Technologists is a valuable program to improve students' professional skills and build relationships between local companies and university students.However, the impact of this internship on students' employment awareness has not been fully analyzed. Then, as one of the means to solve these problems, Institute of Technologists newly designed and implemented an internship program for the purpose of forming employment awareness of university students. Therefore, in this study, we conducted a survey on the employment consciousness of participating university students for the purpose of clarifying the effect of this new internship on students., 本研究では，CPM インターンシップ参加学生，企業担当者に対して意識調査を行い，就業に関する価値観の変化を分析することによってCPM インターンシップの効果を検証する．

第21回宇宙科学シンポジウム (2021年1月6日-7日. オンライン開催), 21st Space Science Symposium (January 6-7, 2021. Online Meeting), 資料番号: SA6000163121, レポート番号: g19-1

In recent years, many local cities have operated an administratively-led community bus, which is one of the means of transportation for residents, but it is difficult to operate public transport that accurately captures regional characteristics and residents' usage intentions, etc. There are not a few areas in which service levels are reduced and services are being run by the reduction of users.In Nagatoro Town, Chichibu-gun, Saitama Prefecture, residents, especially vulnerable people such as elderly people who can not drive a car, have difficulty moving because there is no public transport service such as a community bus that operates the town. In this study, in order to explore the optimum operation mode of public transport service in Nagatoro Town with the above problems, not only the request on the operation mode of the local residents but also the availability of public transport considering the characteristics of daily travel and The purpose is to grasp the potential travel demand and to conduct a basic study on the ideal operation mode of public transport service., 本研究では，上記の問題を抱える長瀞町において公共交通サービスの最適な運行形態を探るため，地域住民の運行形態に関する要望のみならず，普段の移動の特性を考慮した公共交通の利用可能性および潜在的な移動需要を把握し，公共交通サービスの理想的な運行形態について基礎的な検討を行うことを目的とする．また，本研究の成果は長瀞町の地域公共交通網形成計画に反映される予定である．

Recently, polypentagonal water networks were observed in a protein capable of binding to ice crystals, or ice-binding protein (IBP). To examine such water networks and clarify their role in ice-binding, we determined X-ray crystal structures of a 65-residue defective isoform of an IBP (wild type, WT) and its 5 single mutants (A20L, A20G, A20T, A20V, and A20I). Polypentagonal water networks composed of approximately 50 semi-clathrate waters were solely observed on the strongest A20I mutant, which appeared to include a tetrahedral water cluster exhibiting perfect position match to the (10-10) 1st prism plane of a single ice crystal. Inclusion of another symmetrical water cluster in the polypentagonal network showed a perfect complementarity to the waters constructing the (20-21) pyramidal ice plane. The order of ice-binding strength was A20L < A20G < WT< A20T < A20V < A20I, where the top 3 mutants capable of binding to the 1st 12 prism and the pyramidal ice planes commonly contained a bifurcated γ-CH313 -group. These results suggest that a fine-tuning of the protein surface assisted by a side-chain group regulates the holding property of the polypentagonal water network, whose function is to freeze the host protein to specific ice planes.

第20回宇宙科学シンポジウム (2020年1月8日-9日. 宇宙航空研究開発機構宇宙科学研究所(JAXA)(ISAS)相模原キャンパス), 相模原市, 神奈川県, 20th Space Science Symposium (January 8-9, 2020. Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency(JAXA)(ISAS)Sagamihara Campus), Sagamihara, Kanagawa Japan, 著者人数: 28名, 資料番号: SA6000152083, レポート番号: P1.57

Recently, there has been growing interest in studying the dynamical behaviors of continuous maps of one-dimensional spaces. Especially, one of the central questions in the theory of dynamical systems is how to recognize "chaos". The theme of this paper is to describe visually the chaoticity of ..., 1999