1. Optimisation of a high-resolution whole-body MR angiography protocol with parallel imaging and biphasic administration of a single bolus of Gd-BOPTA: Preliminary experience in the systemic evaluation of atherosclerotic burden in patients referred for endovascular procedures
- Author
-
Napoli, Alessandro, Anzidei, Michele, CAVALLO MARINCOLA, Beatrice, Zaccagna, Fulvio, Geiger, Daniel, Di Paolo, P. L., Zini, Chiara, Catalano, Carlo, Passariello, Roberto, DI PAOLO, PIER LUIGI, Napoli A., Anzidei M., Marincola B.C., Zaccagna F., Geiger D., Di Paolo P.L., Zini C., Catalano C., and Passariello R.
- Subjects
Male ,Systemic vessels ,Atherosclerosis ,MR angiography ,Whole-body imaging ,Adult ,Aged ,Aged, 80 and over ,Aorta ,Arterial Occlusive Diseases ,Carotid Stenosis ,Clinical Protocols ,Female ,Humans ,Meglumine ,Middle Aged ,Peripheral Vascular Diseases ,Predictive Value of Tests ,Preoperative Care ,ROC Curve ,Reproducibility of Results ,Retrospective Studies ,Sensitivity and Specificity ,Treatment Outcome ,Whole Body Imaging ,Contrast Media ,Magnetic Resonance Angiography ,Organometallic Compounds ,Vascular Surgical Procedures ,Radiology, Nuclear Medicine and Imaging ,Magnetic resonance angiography ,Nuclear Medicine and Imaging ,80 and over ,Neuroradiology ,medicine.diagnostic_test ,Ultrasound ,Interventional radiology ,General Medicine ,Single bolus ,Systemic vessel ,Atherosclerosi ,cardiovascular system ,Radiology ,medicine.medical_specialty ,Whole body imaging ,medicine ,Radiology, Nuclear Medicine and imaging ,In patient ,cardiovascular diseases ,business.industry ,Parallel imaging ,business - Abstract
This study was performed to validate a highresolution whole-body magnetic resonance angiography (MRA) protocol with parallel imaging and biphasic administration of a single bolus of contrast agent in the preliminary assessment of systemic atherosclerotic burden in patients referred for endovascular procedures. Forty patients referred for endovascular treatment of atherosclerotic disease of the carotid arteries (n=23), peripheral vessels (n=14) or aorta (n=3) on the basis of previous clinical and diagnostic examinations underwent high-resolution whole-body MRA at 1.5 T with 3D spoiled gradient recalled echo (GRE) sequences, featuring parallel imaging acquisition technique with ×2 acceleration factor. Sixty-eight surface coil elements and a four-station imaging protocol were employed. Biphasic intravenous administration of a paramagnetic contrast agent [gadolinium benzyloxyproprionic- tetraacetic acid (Gd-BOPTA)] was performed with the following protocol: 10 ml at a speed of 1 ml/s followed by further 10 ml at a speed of 0.5 ml/s. For image analysis, the arterial system was divided into 42 segments for evaluation. The presence or absence of atherosclerotic lesions was evaluated by two observers in consensus; segments were classified as having clinically significant disease (≥50% stenosis or an aneurysmal dilatation) or no significant disease (
- Published
- 2009