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2. [In-vitro action of manganese on platelet aggregation. Hints on prevention].

Author

Fimiani R, Serpico P, and Ciorra A

Subjects
Adenosine Diphosphate pharmacology, Collagen pharmacology, Epinephrine pharmacology, Humans, Thromboplastin pharmacology, Manganese pharmacology, Platelet Aggregation drug effects
Abstract

The AA. carried out some researches on PAT by adding to the plasma the manganic chloride in mu molar, c molar and m molar solution. The platelet aggregation induced by ADP, adrenaline, collagen and thrombofax, makes powerful in presence of manganese salt. The presence of manganic chloride modifies the platelet aggregation in a hyper-aggregated way, slowly and tardly, but clearly. The practical application of experimental results in vitro is certainly very important for prevention planning.

Published
1982

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