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This study investigates the female body and its symbolic deconstruction that occurred following the double atomic bombings of Hiroshima and Nagasaki (1945) as well as the more recent nuclear accident at the Fukushima Daiichi power plant (2011). By adopting an interdisciplinary perspective, this research explores the legacy of the ryōsai kenbo (‘good wife, wise mother’) model and how radioactivity exposure disrupted that ideal by transforming radioactivity-contaminated women into ‘monsters’. Postfeminist theories on the ‘monstrous-feminine’ are implemented to read testimonies on radiophobia, starting from Hayashi Kyōko’s production, the case study of the Hiroshima Maidens and Sono Sion’s movie Land of Hope (2012). The aim is to prove how the radioactivity agency deconstructed the female body as a mere reproductive resource and encouraged an emergent vision of its reconstruction as a woman-individual, claiming her active participation as a social actor.

Introduction: This study aims to evaluate the persistence, treatment adherence and drug cost associated with biologic and targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) in the management of psoriatic arthritis (PsA) in Italy, with a focus on biosimilar drugs. Methods: This was a retrospective observational study involving eight hospital pharmacies, between January 2017 and December 2020, on naïve patients with at least one b/tsDMARD dispensation indicated for PsA. Patients were followed up for 12 months and persistence and adherence were evaluated by proportion of days covered (PDC). The originator and biosimilar for adalimumab and etanercept were compared. Furthermore, the real annual cost per patient based on adherence to therapy was calculated. Results: Patients initiating b/tsDMARDs for PsA had a mean persistence of 263 days and 48.6% remained persistent for 1 year. Adherent patients (PDC ≥ 0.8) were 47.6% for the overall population. Similar persistence and adherence were observed between patients treated with the adalimumab originator and its biosimilar, while patients treated with the etanercept originator showed lower persistence and adherence compared to those treated with its biosimilar (mean persistence: 222 vs. 267 days, patient persistent at 1 year: 29.4% vs. 51.5%, mean PDC: 0.53 vs. 0.70, adherent patients: 23.5% vs. 51.5%). The average annual drug cost ranged from €8,724 (etanercept) to €14,783 (ustekinumab), with an annual saving of more than €2,500 by using biosimilars. Conclusion: Poor adherence to medications contributes to suboptimal clinical outcomes. The comparison between biosimilar and originator offers further evidence in support of the biosimilar to optimizing resources in healthcare.

The global entertainment world has recently seen an increase in post-apocalyptic products, clearly reflecting a public demand for catastrophe-related narratives. This ‘catastrophilia’ finds a relevant example in the dystopian works by Komatsu Sakyō, one of Japan's most celebrated science fiction authors, beginning with the first novel Nihon chinbotsu (1973). Having become a transmedia product thanks to film, manga, and anime adaptations, the story portrays a fictional version of “The Big One” able to sink the entire Japanese archipelago in an unknown future. What is the reason behind such success? By adopting an interdisciplinary perspective intertwining psychological, philosophical and media studies, this paper examines the popularity achieved by Japan Sinks and its mediascape to unveil the addiction to the apocalyptic narratives that goes beyond the ecotopic purpose of re-establishing a symbiotic contact between humans and the environment. Instead, it results from a pathological desire for violence and death and an atavistic tendency for morbid curiosity.

In 1961, the Eichmann trial opened in Jerusalem, and its worldwide resonance through media coverage questioned the collective conscience about responsibility for Nazi crimes. German philosopher Hannah Arendt attended the process as a special correspondent for the U.S. magazine The New Yorker. Her Eichmann in Jerusalem: A Report on the Banality of Evil (1963) caused a great scandal: the author advanced the brazen idea of collective co-responsibility for Nazi crimes, reporting the identikit of a standard bureaucrat, a seemingly ordinary man, just like any one of us. Almost sixty years after its publication, this study adopts a primarily psycho(patho)logical perspective to reflect once again on the considerations Arendt shared in the Banality of Evil. In showing the multiple facets of banality, the research investigates recent results in the analysis of the criminal mind in order to shed light on the etiology of evil.

The Little Prince by Antoine de Saint-Exupéry is one of the world's most successful literary examples of transmediality. Its multiple retellings have ranged from film to animation, amplifying that favorable public and critical response with which the original novella was received. Among them, Shiine Yamato's fukushima no ōjisama (2011) stands as a rewrite of Saint-Exupéry's masterpiece in a post-Fukushima key. This study aims to understand the author's reasons for adopting precisely The Little Prince as a source of inspiration to depict childhood marked by the danger of radioactivity and the prevailing radiophobia in the post-nuclear accident scenario. In doing so, the investigation adopts a comparative perspective aimed at highlighting the reasons for continuity and rupture between the two works, as well as a psycho(pato)logical approach interested in analyzing the topoi of otherness, attachment, and mourning that are common of two works, evidence of the self-therapeutic effort of the two authors.

The paper takes the New Villaggio Matteotti in Terni, a housing complex designed by Giancarlo De Carlo in the early 1970s, as an observation point from which to measure some of the competences and tools that architectural historians of late modernism have often mobilized. The analysis of the existing literature on the Villaggio brings to identify at least three recurrent ways of understanding the role of the historian. First, the historian as an intellectual exposing the contradictions behind architectural practice. Second, the historian as a philologist and a specialist in the treatment of dedicated archival sources. Third, the historian as a specialist in the study of architectural forms. The analysis suggests that, at least in this case, historians have firmly situated themselves within definitions and ways of understanding the architectural object that had been initially codified by the designer. This raises questions concerning the capacity of architectural history to contribute to radical changes in the interpretation of the built environment.

Temperature is a key factor in vine growth and grape composition (Jones, 2006). Climate change is already having an impact on these parameters in many wine regions, and it is becoming necessary to adapt in order to continue producing quality wines, without strongly altering their typical character (van Leeuwen et al., 2019). One way to adapt could be to modify the vine’s training system. A study of temperature at different heights was carried out in the Bordeaux region to assess whether increasing trunk height could modify the microclimate in the bunch zone (de Rességuier et al., 2023).

This contribution is a commented portfolio of images gathered during fieldwork in Baghdad (February 2020). It aims to provide an overview of the murals which have been concentrated on Tahrir Square since the revolution of October 2019. These murals share some iconographic topics in common with the thawra (revolution) in Syria, Tunisia, Egypt and Beirut. Nevertheless, some semantic and iconographic registers are specific to Iraq, and divided into two main categories. The first one recreates “a city within the city” (ville en abyme) through composite unrealistic images of real places known to all; the second relates to the martyrology of Shiism, with portraits of historical imams, but also of “martyrs” killed during the repression in Autumn 2019. Contrary to the well-known official iconography since the 1958 Iraqi revolution, this new figurative expression is that of a young population predominantly Shiite (due to demography in Iraq), and it stems from a cultural and political substrate prone to rebellion—that of Hussein, long repressed by power. The style is often naive, at the antipodes of the concomitant Beiruti thawra street art, although crossing with other globalized graphic codes. It constitutes a vibrant popular culture and also signals a “Shiitization” of public space. Beyond traditional divisions, it finally proves to federate, in reaction to the iconoclasm of Daesh but also to the corruption that strikes the daily life and the future of millions of citizens.

L’articolo riflette sugli immaginari legati al commercio a partire da una ricerca in corso sulla pianificazione e realizzazione dei quartieri PEEP italiani. La legge 167 (1962) e una serie di provvedimenti successivi rappresentarono, nelle intenzioni dei loro promotori, un momento fondativo per la costruzione di una nuova generazione di quartieri a grande scala capaci di generare nuove forme di urbanità. Quale ruolo ebbe il commercio all’interno di un simile processo? Appoggiandosi a un piccolo numero di studi di caso, la ricerca enuncia l’ipotesi che portare il fuoco dell’osservazione sulla questione del commercio permetta di cogliere alcuni dei nodi irrisolti dietro le sperimentazioni del secondo dopoguerra intorno alla “grande dimensione”. A differenza di quanto accaduto in diverse esperienze internazionali del periodo nel campo dell’urban design, le culture architettoniche e urbanistiche italiane faticarono a riconoscere nell’emergente dimensione del consumo di massa il possibile fondamento di nuove forme di socialità e di cittadinanza. The article reflects on the images related to commerce, taking the lead from ongoing research on the planning and implementation of Italian PEEP (Plans for Economic and Public Housing) schemes. In the intentions of their promoters, Law 167 (1962) and a series of subsequent measures represented a founding moment for the construction of a new generation of large-scale residential neighborhoods capable of generating new forms of urbanity. What role did commerce play within such a process? Relying on a small number of case studies, the research formulates the hypothesis that focusing on the issue of commerce allows us to address some of the unresolved questions behind the post-World War II experiments around the issue of the grande dimensione (‘great dimension’). Unlike several international experiences of the time in the field of urban design, Italian architectural and urban cultures struggled to recognize in the emerging mass consumption the possible foundation of new forms of sociality and citizenship.

The digression of Verg. georg. III 339-383 depicts the life of Libyan and Scythian shepherds, inserting positive or even utopian features in a mainly dystopian context: such ambiguity could be explained as aiming at those paradox and thaumasion that are distinctive of Virgilian didactic poetry, but also by historical-political reasons. The slight lack of consistency of this passage motivates both the different interpretations by modern critics, and the opposite reception by Horace, who in carm. III 24 transforms Virgil’s dystopian Scythians into a utopian ethical model, and Ovid, who in trist. III 10 and Pont. IV 7 retains only the negative elements in order to represent his personal dystopia: being a poet banished far from Rome, to the savage borders of the Empire.

L’apprendimento a distanza rappresenta un grande potenziale per le piccole scuole, richiede però di ripensare la forme scolaire per queste ultime. Indire, in collaborazione con il Centre scolaire du Fleuve et des Lacs (Ministère de l’éducation et de l’enseignement supérieur du Québec), la Italian University Line (IUL), l’Ufficio Scolastico Regionale (USR) Abruzzo e un esperto dell’Università della Valle d’Aosta, ha promosso un intervento di formazione e sperimentazione per aiutare i docenti delle piccole scuole ad attuare il modello “Classi in rete” sviluppato dall’École éloignée en Réseau (Allaire et al., 2009) e basato sull’approccio teorico delle Knowledge Building Communities.

This article aims to illustrate a flipped classroom experimentation that took place in a high school in the city of Piacenza, in northern Italy. The “E-school” section has been activated in this school since 2013. This research began at the end of the second five-year period of the experimentation (2018/2019) with the aim of carrying out a first evaluation and returning a description that allows to highlight elements of interest and any critical issue with reference to four emerging dimensions: ● activelearningandinclassactivities; ● contentandaudiovisualpodcasts; ● autonomous learning, responsibility, evaluation; ● social learning and key competencies.

The Italian Society of Clinical Biochemistry and Molecular Biology (SIBioC) has long promoted harmonizing activities, focusing on the laboratory reports to guarantee accuracy and comparability of the results. There is a wealth of guidelines on the clinical usefulness and diagnostic accuracy of serum protein electrophoresis (SPE), but only few provide specific recommendations for reporting and commenting the results. According to surveys and international multi-center studies, there is considerable variability between SPE reports among laboratories, which negatively impacts the management of patients with monoclonal gammopaties (MGs). This document issued by the SIBioC Study Group on Proteins, provides guidance on how to standardize and harmonize laboratory SPE reports, formulated on the basis on the available reference literature as well as on expert consensus. Each SPE report should be accompanied by a descriptive comment, mainly related to the management of samples with monoclonal components (detection, quantification and immunotyping). Examples of comments are provided. Special attention should be dedicated to samples showing a possible interference by therapeutic monoclonal antibodies (tmAb) currently used for the treatment of Multiple Myeloma (MM). Failure to detect interference due to tmAb can lead to further unnecessary diagnostic procedures or incorrect interpretations of the efficacy of treatment, such as the failure to detect a complete response to treatment in MM patients. Close collaboration between laboratory professionals and clinicians is therefore of paramount importance to provide correct information that will be useful in every step of the management of MGs patients. [ABSTRACT FROM AUTHOR]

The presence of the Spotless Starling in Sicily was reported for the first time at the beginning of the XIX century, although the first nests for the province of Trapani are reported almost at the end of the XX century. As a breeder, the Spotless Starling remained absent from all the circumsicilian islands until the first report for the island of Pantelleria, in 2012. In 2020, the nest of Spotless Starling was observed on the island of Favignana, within a hole on an antenna. The couple fed the chicks with Ligia italica crustacean isopod of the family Ligiidae. The nesting on the island of Favignana confirms the continuous expansion of the species in Sicily.

Questo contributo si focalizza sui rapporti scuola genitori nelle piccole scuole. Ad ora, anche a livello internazionale, sono pochi gli studi che riguardano nello specifico i rapporti scuola genitori nelle piccole scuole, mentre la maggior parte delle ricerche sul tema è stata condotta in contesti urbani o suburbani. Dopo una rassegna sulla letteratura internazionale relativa ai rapporti scuola genitori nelle piccole scuole verranno presentati i principali risultati emersi da una ricerca realizzata nelle piccole scuole delle montagne piemontesi negli anni scolastici 2017/2018 e 2018/2019.

Miguel Delibes, Cinque ore con Mario (versione teatrale), a cura di Renata Londero, Venezia, Marsilio 2017, 179 pp. ISBN 9788831727273.

Textual agency plays a fundamental role with regard to the literary production devoted to catastrophic events and the trauma they entail; it raises questions about the ethics of the disaster, as if to say the legitimacy of the literary works on the theme. The authorial commitment to bear witness to the events often clashes with the unrepresentability of the event itself: silence and discursivity are both misleading choices in the sense that the first is a real blot on History, while the latter implies to domesticate trauma in order to transpose it into literary forms. This article aims to give relevance to the therapeutic agency of the Literature of the catastrophe and in doing so, it contributes to the re-evaluation of the genre as part of the literary canon.

Background: sepsis is a serious disease with high mortality rate, threatening human health. Clinicians need to diagnose the condition in time to develop an effective treatment plan; therefore, a quick and early screening to rule in or rule out sepsis has become an urgent problem in clinical laboratories. Different markers are used to diagnose sepsis, but they have limitations and require additional examination. The aim of this study is to use leucocyte count and other haematological parameters obtained by Mindray BC-6800-plus, to identify sepsis biomarkers that are early, quickly, conveniently, and at low cost. Methods: a total of 479 venous whole blood samples were collected: 63 control samples (blood donors), and 416 samples hospitalized at the emergency department with symptoms attributable to sepsis with a procalcitonin request. Morphometric parameters are reported using Mindray BC-6800 plus analyzer: white blood cell count-related parameters like cell population data named X, Y, Z, neutrophil-lymphocyte ratio, and index of immature granulocytes. Statistical analysis was performed using the Kruskal-Wallis test to evaluate significative differences among the groups. ROC curves were also examined to extrapolate a cut-off of pathogenicity. Results: we found a significant statistically difference between the control and the sepsis groups for a number of haematological parameters. The ROC curves highlight acceptable sensitivity and specificity values for some parameters, and suggest possible cut-offs. Discussion: some qualitative and quantitative parameters of total count blood can be of help with the screening of sepsis upon admission to the emergency department. [ABSTRACT FROM AUTHOR]

According to Silvio D’Amico and the Fascist regime, staging La Figlia di Iorio at the 1934 Volta Conference would show the world a perfect example of the rising Italian direction, especially considering that high-level international figures joined to rewrite this masterpiece in Mediterranean rustic literature, thirty years after Michetti’s and Talli’s realistic and pictorial legendary première. However, putting together avant-garde and tradition was a gamble that did not work out. Pirandello, De Chirico, Ruggeri and Marta Abba (who had been recommended) reluctantly participated in the endeavour and did not manage to meet expectations. This was the umpteenth missed opportunity in the history of Italian theatre, and d’Annunzio polemically distanced himself from it .

Emotional aspects play an important role in promoting well-being at school and are linked to the development of self-care skills, which enable people to cope with stress and make a positive contribution to their community (Moses, Bradley & O'Callaghan, 2016). Young people often experience emotional distress and negative moods, making them vulnerable and at risk of academic failure (Ahonen, Nebot & Giménez, 2007; Thompson & Tawell, 2017). School achievement is in fact linked to the development of emotional skills implicit in the processes of self-regulation, coping with stress and in the ability to collaborate both with peers and adults (Zimmerman, 2008). Starting from these premises, the contribution presents some preliminary data of an action research started with some secondary schools with the aim of experimenting with strategies that can be recognized as significant in promoting emotional wellbeing and self-care skills in students. [ABSTRACT FROM AUTHOR]

Although the Fukushima literary scenario offers different approaches to the theme of dystopia and trauma, works of literary criticism are still a few. This article aims to turn scholars’ attention to the relevance of a critic analysis of Fukushima literary response starting from the production of Wagō Ryōichi and his poetical tweets. The purpose is to suggest new study guidelines concerning the literature of the catastrophe as a genre itself, thorough the investigation of the use of words as a vehicle of memory and by extension, the social role of literature towards catastrophe. Wagō’s works also offer the chance to investigate the relationship between literature and social networks, in so far as the success of Wagō’s net-poetry raises concerns about the development of this global communication system to overcome trauma in real time; as a new mean of literary expression, Wagō’s net-poetry also contributes to the literary debate by spreading literary works all over the world in just one click.