1. [Intestinal malabsorption, celiac disease and associated lymphoma: from symptoms to diagnosis].
- Author
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Gasbarrini G, Corazza GR, Biagi F, Brusco G, Andreani ML, Malservisi S, and Greco AV
- Subjects
- Adult, Celiac Disease diagnosis, Celiac Disease physiopathology, Female, Humans, Intestinal Neoplasms diagnosis, Intestinal Neoplasms physiopathology, Lymphoma diagnosis, Lymphoma physiopathology, Malabsorption Syndromes diagnosis, Malabsorption Syndromes physiopathology, Male, Middle Aged, Celiac Disease complications, Intestinal Neoplasms complications, Lymphoma complications, Malabsorption Syndromes complications
- Abstract
The clinical consequences of intestinal malabsorption are extremely variable and a dissociation between malabsorption, malabsorption syndrome and enteropathy is often noted. Enteropathy does not always results in malabsorption and in an alteration of the tests exploring the absorptive function. The following have particular relevance in clinical practice: coeliac disease, malabsorption induced by microbiologic agent (including Whipple's disease), post-surgical malabsorption and selective carbohydrate malabsorption. In particular, coeliac disease has been analyzed in its various aspects, from studies with organ cultures to immunological hypotheses, from the classical variety to subclinical forms and to serious complications, such as enteropathy-associated T cell lymphoma. Malabsorption syndromes are dramatically underdiagnosed: in the typical case of coeliac disease, enteropathy represents a clinical iceberg, and the discovery of the submerged portion, represented by the polymorphous subclinical varieties, has just started. As far as intestinal malabsorption is concerned, the main clinical problem regards diagnosis.
- Published
- 1994